GLS2 antibody

Catalog No. ABIN6243842

Product Details anti-GLS2 Antibody

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This GLS2 antibody is generated from a mouse immunized with a recombinant protein of human GLS2.

Clone: 1758CT879-217-60

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000-1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for GLS2

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Alternative Name: GLS2 (GLS2 Products)

Synonyms: si:ch211-216k22.10 antibody, GA antibody, GLS antibody, LGA antibody, hLGA antibody, A330074B06Rik antibody, AI195532 antibody, Lga antibody, Ga antibody, glutaminase 2 antibody, glutaminase 2a (liver, mitochondrial) antibody, glutaminase 2 (liver, mitochondrial) antibody, glsA2 antibody, LOAG_03311 antibody, gls2a antibody, GLS2 antibody, Gls2 antibody

Background: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.

Molecular Weight: 66323

UniProt: Q9UI32

Pathways: Dicarboxylic Acid Transport, Warburg Effect