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Browse our anti-Aprataxin (APTX) Antibodies

Full name:
anti-Aprataxin Antibodies (APTX)
On www.antibodies-online.com are 45 Aprataxin (APTX) Antibodies from 12 different suppliers available. Additionally we are shipping Aprataxin Proteins (22) and Aprataxin Kits (2) and many more products for this protein. A total of 74 Aprataxin products are currently listed.
Synonyms:
2410016G21Rik, AA388047, AOA, AOA1, APRATAXIN-like, APTX, AXA1, EAOH, EOAHA, FHA-HIT, LOC100284636, T10O8.20, T10O8_20

Most Popular Reactivities for anti-Aprataxin (APTX) Antibodies

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anti-Human Aprataxin Antibodies:

anti-Mouse (Murine) Aprataxin Antibodies:

anti-Rat (Rattus) Aprataxin Antibodies:

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Top referenced anti-Aprataxin Antibodies

  1. Chicken Polyclonal Aprataxin Primary Antibody for IHC, WB - ABIN2778569 : Ahnesorg, Smith, Jackson: XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. in Cell 2006 (PubMed)
    Show all 2 references for ABIN2778569

  2. Cow (Bovine) Polyclonal Aprataxin Primary Antibody for WB - ABIN2777648 : Yoon, Westmacott, MacMillan, Quercia, Koutsou, Georghiou, Christodoulou, Banwell: Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. in Journal of neurology, neurosurgery, and psychiatry 2008 (PubMed)

More Antibodies against Aprataxin Interaction Partners

Human Aprataxin (APTX) interaction partners

  1. Lack of aprataxin impairs mitochondrial functions via downregulation of the APE1 (show APEX1 Antibodies)/NRF1 (show NFE2L1 Antibodies)/NRF2 (show GABPA Antibodies) pathway.

  2. Herein, we survey APTX function and the emerging cell biological, structural and biochemical data that has established a molecular foundation for understanding the APTX mediated deadenylation reaction. [review]

  3. We describe an ataxia (show USP14 Antibodies) with oculomotor apraxia type 1 patient without a severe phenotype, who has a homozygous deletion of the complete coding region of APTX.

  4. TDP1 (show TDP1 Antibodies) and APTX take part in the mitochondrial DNA repair and are apparently being transported from the cell nucleus. (Review)

  5. Structure-function studies of human APTX-RNA-DNA-AMP (show APRT Antibodies)-Zn complexes define a mechanism for detecting and reversing adenylation at RNA-DNA junctions

  6. Data suggest that mutations affecting protein folding, the active site pocket and the pivot motif underlie aprataxin dysfunction in the neurodegenerative disorder ataxia (show USP14 Antibodies) with oculomotor apraxia 1 (AOA1).

  7. The clinical phenotype was homogeneous, irrespectively of the type and location of the APTX mutation, and it was mainly characterized by early-onset cerebellar signs, sensory neuropathy, cognitive decline, and oculomotor deficits.

  8. Aprataxin is required for the normal repair rate of DNA single-strand breaks induced by genotoxic agents.

  9. The patients with early onset ataxia (show USP14 Antibodies) with ocular motor apraxia and hypoalbuminaemia homozygous for the c.689_690insT mutation(APTX) show a more severe phenotype than those with a p.Pro206Leu or p.Val263Gly mutation.

  10. Aprataxin localizes to mitochondria and preserves mitochondrial function.

Mouse (Murine) Aprataxin (APTX) interaction partners

  1. Study demonstrates a protective role of Aptx in vivo and suggests that its loss results in progressive accumulation of DNA breaks in the nervous system, triggering hallmarks of premature ageing, systemically.

  2. neurological disorders associated with APTX mutations may be caused by the gradual accumulation of unrepaired DNA strand breaks resulting from abortive DNA ligation events

  3. aprataxin participates in chromosomal single-strand break repair

Aprataxin (APTX) Antigen Profile

Antigen Summary

This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.

Alternative names and synonyms associated with Aprataxin (APTX)

  • FHA-HIT protein (aptx) antibody
  • FHA-HIT (aptx) antibody
  • aprataxin (APTX) antibody
  • aprataxin (CpipJ_CPIJ001673) antibody
  • aprataxin (aptx) antibody
  • aprataxin (LOC100284636) antibody
  • adenylylsulfate sulfohydrolase (APTX) antibody
  • aprataxin (Aptx) antibody
  • FHA-HIT long isoform (aptx) antibody
  • 2410016G21Rik antibody
  • AA388047 antibody
  • AOA antibody
  • AOA1 antibody
  • APRATAXIN-like antibody
  • APTX antibody
  • AXA1 antibody
  • EAOH antibody
  • EOAHA antibody
  • FHA-HIT antibody
  • LOC100284636 antibody
  • T10O8.20 antibody
  • T10O8_20 antibody

Protein level used designations for anti-Aprataxin (APTX) Antibodies

aprataxin , forkhead-associated domain histidine triad-like protein , aprataxin-like , FHA-HIT , forkhead-associated domain histidine-triad like protein , forkhead-associated domain histidine-triad like

GENE ID SPECIES
403092 Xenopus (Silurana) tropicalis
445730 Ciona intestinalis
465037 Pan troglodytes
702671 Macaca mulatta
6032646 Culex quinquefasciatus
100068091 Equus caballus
100194567 Salmo salar
100284636 Zea mays
100439490 Pongo abelii
830940 Arabidopsis thaliana
100592983 Nomascus leucogenys
54840 Homo sapiens
398657 Xenopus laevis
442943 Canis lupus familiaris
387596 Sus scrofa
66408 Mus musculus
259271 Rattus norvegicus
395173 Gallus gallus
359714 Bos taurus
405797 Danio rerio
445995 Takifugu rubripes
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