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Aprataxin Products

(Aprataxin (APTX))

Categories

This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010].

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Featured Aprataxin Categories

Aprataxin Antibodies

High quality antibodies with extensive validation data.

Aprataxin ELISA Kits

Reliable ELISA kits for a wide range of species.

Aprataxin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Aprataxin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN527215
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (3)
Cat. No. ABIN6137038
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7235888
Quantity 200 μL
Datasheet Datasheet

Recommended Aprataxin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964973
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5591659
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1050821
Quantity 96 tests
Datasheet Datasheet

Recommended Aprataxin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121877
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345416
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345418
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Aprataxin products

Sykora, Croteau, Bohr, Wilson: "Aprataxin localizes to mitochondria and preserves mitochondrial function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 18, pp. 7437-42, (2011) (PubMed).

Chu, Qu, Zhong, Artandi, Chang: "Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions." in: Molecular cell, Vol. 44, Issue 4, pp. 667-78, (2011) (PubMed).

Dopeso, Mateo-Lozano, Elez, Landolfi, Ramos Pascual, Hernández-Losa, Mazzolini, Rodrigues, Bazzocco, Carreras, Espín, Armengol, Wilson, Mariadason, Ramon Y Cajal, Tabernero, Schwartz, Arango: "Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2375-82, (2010) (PubMed).

Asai, Hirano, Shimada, Kiriyama, Furiya, Ikeda, Iwamoto, Mori, Nishinaka, Konishi, Udaka, Ueno: "Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin." in: Human molecular genetics, Vol. 18, Issue 19, pp. 3533-43, (2009) (PubMed).

Biton, Dar, Mittelman, Pereg, Barzilai, Shiloh: "Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 17482-91, (2006) (PubMed).

Luo, Chan, Yang, Rodriguez, Chen, Leng, Mu, Chen, Songyang, Wang, Qin: "A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment." in: Molecular and cellular biology, Vol. 24, Issue 19, pp. 8356-65, (2004) (PubMed).

Synonyms and alternative names related to Aprataxin

aprataxin (aptx), FHA-HIT (aptx), aprataxin (APTX), aprataxin (CpipJ_CPIJ001673), aprataxin (LOC100284636), APRATAXIN-like protein (APTX), aprataxin L homeolog (aptx.L), aprataxin (Aptx), 2410016G21Rik, AA388047, AOA, AOA1, APRATAXIN-like, aptx, APTX, AXA1, EAOH, EOAHA, FHA-HIT, LOC100284636, T10O8.20, T10O8_20

Protein level used designations for Aprataxin

  • aprataxin
  • forkhead-associated domain histidine triad-like protein
  • aprataxin-like
  • FHA-HIT
  • forkhead-associated domain histidine-triad like protein
  • forkhead-associated domain histidine-triad like
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