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Browse our anti-MutY Homolog (E. Coli) (MUTYH) Antibodies

Full name:
anti-MutY Homolog (E. Coli) Antibodies (MUTYH)
On www.antibodies-online.com are 95 MutY Homolog (E. Coli) (MUTYH) Antibodies from 22 different suppliers available. Additionally we are shipping MutY Homolog (E. Coli) Kits (18) and MutY Homolog (E. Coli) Proteins (6) and many more products for this protein. A total of 128 MutY Homolog (E. Coli) products are currently listed.
Synonyms:
5730495A01Rik, CYP2C, MGC145569, MUTYH, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh
list all antibodies Gene Name GeneID UniProt
MUTYH 4595 Q9UIF7
MUTYH 70603 Q99P21
MUTYH 170841 Q8R5G2

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All available anti-MutY Homolog (E. Coli) Antibodies

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Top referenced anti-MutY Homolog (E. Coli) Antibodies

  1. Human Monoclonal MUTYH Primary Antibody for IP, RNAi - ABIN561883 : van der Post, Kets, Ligtenberg, van Krieken, Hoogerbrugge: Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis. in Virchows Archiv : an international journal of pathology 2008 (PubMed)
    Show all 7 references for ABIN561883

  2. Human Polyclonal MUTYH Primary Antibody for EIA, FACS - ABIN953552 : Kim, Cho, Park, Kim, Nam, Lee, Yoo, Lee, Park: Genetic alterations of the MYH gene in gastric cancer. in Oncogene 2004 (PubMed)
    Show all 3 references for ABIN953552

  3. Human Polyclonal MUTYH Primary Antibody for EIA, WB - ABIN375216 : Slupska, Baikalov, Luther, Chiang, Wei, Miller: Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. in Journal of bacteriology 1996 (PubMed)

  4. Human Polyclonal MUTYH Primary Antibody for IF, ELISA - ABIN1534474 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against MutY Homolog (E. Coli) Interaction Partners

Horse (Equine) MutY Homolog (E. Coli) (MUTYH) interaction partners

  1. qPCR analysis of cDNA from the cerebella of affected and unaffected horses suggested that MUTYH expression is down-regulated in affected horses.

Human MutY Homolog (E. Coli) (MUTYH) interaction partners

  1. A mutation in both a MUTYH and either a MLH1 (show MLH1 Antibodies), MSH2 (show MSH2 Antibodies) and PMS2 (show PMS2 Antibodies) gene mutation is associated with colorectal cancer.

  2. Expression of APC (show APC Antibodies) is decreased in mutation negative cases and this appears to be a promising indicator of FAP predisposition, while for MUTYH gene, mutation is associated to reduced mRNA expression.

  3. MUTYH mutations are prevalent among Jews of North-African origin with colorectal adenomas.Increased risk for colorectal adenomas and cancer in mono-allelic MUTYH mutation carriers among among Jews of North-African origin.

  4. We demonstrated that the rs3219463 and rs3219476 polymorphisms in RA patients from a Taiwan Chinese population were associated with disease susceptibility. These data indicate that the MUTYH gene may play a role in the progression of RA.

  5. 47 MUTYH gene variants (site-directed mutagenesis) were generated, the proteins expressed in MutY-disrupted E. coli, and assessed their abilities to complement the functional deficiency in the E. coli by monitoring spontaneous mutation rates.

  6. The results of this study suggested that the MUTYH gene polymorphisms may play an important role in the etiology of Alzheimer's Disease.

  7. adenine glycosylase activity, mismatch recognition properties and interaction with protein partners of MUTYH and 5 MAP variants were examined; P502L and R520Q had reduced affinity for PCNA (show PCNA Antibodies); only Q324H was found to have reduced affinity for Hus1 (show HUS1 Antibodies)

  8. Results showed that AluYb8MUTYH variant was associated with high level of altered mtDNA in type 2 diabetes mellitus patients that may have resulted from inefficient base excision repair of MUTYH and a mechanism trigerred by elevated oxidative stress.

  9. As well as MUTYH Tyr/Tyr (show TYR Antibodies) and XPD (show ERCC2 Antibodies) Asp (show ASIP Antibodies)/Asn genotypes further increased the risk by 2.9.

  10. Individuals with biallelic MUTYH mutations in MUTYH-associated polyposis are under-ascertained based on both genotype and phenotype under current standard testing practices.

Mouse (Murine) MutY Homolog (E. Coli) (MUTYH) interaction partners

  1. MUTYH loss is associated with an increase in inflammation associated colorectal cancer risk, which involves immunosuppression and altered inflammatory response.

  2. Results show that MYH is a vital DNA repair enzyme (show LIG4 Antibodies) that protects cells from oxidative DNA damage and is critical for a proper cellular response to DNA damage.

  3. a 5-methylcytosine glycosylase activity for the murine DNA base excision repair enzyme Myh is described and shown that it is critically involved in remodeling the IL-2 (show IL2 Antibodies) Promoter for transcription.

  4. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (show OGG1 Antibodies), Neil1 (show NEIL1 Antibodies), Mutyh and Xrcc1 (show XRCC1 Antibodies) in the brain of adult offspring.

  5. The action of MUTYH, which initiates excision repair of adenine opposite 8-oxoG, triggers neurodegeneration in mice.

  6. OGG1 (show OGG1 Antibodies) and MYH appear to be dispensable for antimutator function in mitochondria.

  7. Mutyh plays a major role in maintaining intestinal integrity by affecting the inflammatory response.

  8. Aim of this study was to characterize the biological effects, in a mammalian cell background, of human MUTYH mutations identified in MUTYH-associated polyposis patients

  9. Replication-associated repair of adenine:8-oxoguanine mispairs by MYH

  10. a specific germ-line mutation (G382D) is identified in mutyH which may be responsible for the mutator phenotype

MutY Homolog (E. Coli) (MUTYH) Antigen Profile

Antigen Summary

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MutY Homolog (E. Coli) (MUTYH)

  • mutY homolog (E. coli) (MUTYH) antibody
  • mutY homolog (MUTYH) antibody
  • mutY homolog (mutyh) antibody
  • mutY homolog (LOC100373318) antibody
  • mutY homolog (E. coli) (Mutyh) antibody
  • 5730495A01Rik antibody
  • CYP2C antibody
  • MGC145569 antibody
  • MUTYH antibody
  • Mutyha antibody
  • Mutyhalpha antibody
  • Mutyhb antibody
  • Mutyhbeta antibody
  • Mutyhc antibody
  • Myh antibody

Protein level used designations for MUTYH

mutY homolog (E. coli) , A/G-specific adenine DNA glycosylase , A/G-specific adenine DNA glycosylase-like , mutY homolog , adenine-DNA glycosylase , mMYH , mutY homolog alpha , the full-length form type A, 5' region , rMYH

GENE ID SPECIES
424594 Gallus gallus
456539 Pan troglodytes
482515 Canis lupus familiaris
513051 Bos taurus
100052596 Equus caballus
100397524 Callithrix jacchus
100465330 Ailuropoda melanoleuca
100513867 Sus scrofa
705651 Macaca mulatta
780292 Xenopus (Silurana) tropicalis
100373318 Saccoglossus kowalevskii
4595 Homo sapiens
70603 Mus musculus
170841 Rattus norvegicus
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