MUTYH antibody (C-Term)

Catalog No. ABIN6254179

This Goat Polyclonal antibody specifically detects MUTYH in WB. It exhibits reactivity toward Human, Mouse, Rat, Monkey, Guinea Pig, Sheep, Rabbit, Pig, Horse, Hamster, Goat, Donkey, Dog, Cow, Chicken, Cat and Avian.It has been mentioned in 1 publication

Quick Overview for MUTYH antibody (C-Term) (ABIN6254179)

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivity: Human, Mouse, Rat, Monkey, Guinea Pig, Sheep, Rabbit, Pig, Horse, Hamster, Goat, Donkey, Dog, Cow, Chicken, Cat, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This MUTYH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUTYH Antibody

Binding Specificity: C-Term

Purpose: Anti-MUTYH

Sequence: MKKVFRVYQG QQPGTCMGSK RSQVSSPCSR KKPRMGQQVL DNFFRSHIST DAHSLNSAAQ

Specificity: In 293HEK cells transfected with cds plasmid (myc-his-Mutyh) detects a band of 50 kDa by Western blot.

Characteristics: MutY homolog (E. coli)

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 476 aa to the C-terminus of human Mutyh produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-MUTYH antibody (ABIN6254179)

Ferreira, Rosa Soares, Ramalho, Ribeiro-Rodrigues, Máximo, Zuzarte, Girão, Pereira: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).

Target Details for MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Alternative Name: MUTYH

Background:

Polyclonal antibody to MUTYH. MUTYH is involved in oxidative DNA damage repair. It nicks DNA replication errors, specifically A/G mismatches.

MYH, CYP2C, MGC4416, Myh, Mutyha, Mutyhb, Mutyhc, Mutyhbeta, Mutyhalpha, 5730495A01Rik, MGC156598, MUTYH, MGC128714, MGC145569 antibody.

Pathways: DNA Damage Repair