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MUTYH antibody

MUTYH Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3022243
  • Target See all MUTYH Antibodies
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Reactivity
    • 56
    • 38
    • 19
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 49
    • 4
    • 3
    Rabbit
    Clonality
    • 52
    • 4
    Polyclonal
    Conjugate
    • 34
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUTYH antibody is un-conjugated
    Application
    • 31
    • 19
    • 17
    • 13
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human MUTYH
    Isotype
    IgG
    Top Product
    Discover our top product MUTYH Primary Antibody
  • Application Notes
    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C/-80 °C
  • Target
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Alternative Name
    MUTYH (MUTYH Products)
    Synonyms
    MUTYH antibody, MGC145569 antibody, CYP2C antibody, MYH antibody, 5730495A01Rik antibody, Mutyha antibody, Mutyhalpha antibody, Mutyhb antibody, Mutyhbeta antibody, Mutyhc antibody, Myh antibody, mutY DNA glycosylase antibody, mutY homolog (E. coli) antibody, A/G-specific adenine DNA glycosylase-like antibody, MUTYH antibody, mutyh antibody, LOC100373318 antibody, Mutyh antibody
    Background
    Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches. Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria. MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage. Research studies have shown that mutations in the corresponding MYH gene are associated with human gastric and colorectal cancers.
    Synonyms: MGC4416, MYH
    Gene ID
    4595
    UniProt
    Q9UIF7
    Pathways
    DNA Damage Repair
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