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POLK Proteins

(Polymerase (DNA Directed) kappa (POLK))

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].

recommended

POLK Protein (ABIN2452172)

POLK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS-PAGE (CBB staining) ELISA, WB, Func Active

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recommended

POLK Protein (AA 1-472) (GST tag) (ABIN1315652)

POLK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

POLK Protein (AA 1-560) (His tag) (ABIN7124513)

POLK Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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POLK Proteins by Grade

Find POLK Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

POLK Proteins by Origin

Find POLK Proteins for a variety of species such as anti-Human POLK, anti-Mouse POLK. The species listed below are among those available. Click on a link to go to the corresponding products.

POLK Proteins by Source

Here you will find POLK Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

POLK Proteins by Protein Type

Here you can find POLK Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

POLK Proteins by Application

Find POLK Proteins validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLK Proteins by Biological Activity

Find POLK Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular POLK Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

POLK Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2452172

Quantity 50 μg

Datasheet Datasheet

POLK Protein (AA 1-472) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1315652

Quantity 10 μg

Datasheet Datasheet

POLK Protein (AA 1-560) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7124513

Quantity 50 μg

Datasheet Datasheet

POLK Protein (AA 1-870) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3094746

Quantity 1 mg

Datasheet Datasheet

POLK Protein (AA 1-852) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3137340

Quantity 1 mg

Datasheet Datasheet

POLK Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719558

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our POLK Proteins

Ohashi, Bebenek, Matsuda, Feaver, Gerlach, Friedberg, Ohmori, Kunkel: "Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39678-84, (2001) (PubMed).

Ohashi, Ogi, Kusumoto, Iwai, Masutani, Hanaoka, Ohmori: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).

Czerkawski, Blaxter, Wainman: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).

Aliases for POLK Proteins

DNA polymerase kappa (POLK) Proteins
DNA polymerase kappa (Polk) Proteins
polymerase (DNA directed) kappa (polk) Proteins
DNA polymerase kappa (Tb11.01.0080) Proteins
DNA polymerase kappa (Tb11.01.0010) Proteins
DNA polymerase kappa (Tb11.01.0020) Proteins
DNA polymerase kappa (Tb11.01.0030) Proteins
DNA polymerase kappa (Tb11.01.0040) Proteins
DNA polymerase kappa (Tb11.01.0050) Proteins
DNA polymerase kappa (Tb11.12.0001) Proteins
DNA polymerase kappa (Tb11.12.0002) Proteins
DNA polymerase kappa (Tb11.12.0003) Proteins
polymerase (DNA directed), kappa (Polk) Proteins
polymerase (DNA directed) kappa L homeolog (polk.L) Proteins
DNA polymerase kappa (polk-1) Proteins
DINB1 Proteins
Dinb1 Proteins
DINP Proteins
POLK Proteins
POLQ Proteins
si:ch211-254o18.3 Proteins

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POLK Proteins by Grade

POLK Proteins by Origin

POLK Proteins by Source

POLK Proteins by Protein Type

POLK Proteins by Application

POLK Proteins by Biological Activity

Popular POLK Proteins

Latest Publications for our POLK Proteins

Aliases for POLK Proteins

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