Browse our anti-XPA (XPA) Antibodies

Full name:
anti-Xeroderma Pigmentosum, Complementation Group A Antibodies (XPA)
On www.antibodies-online.com are 139 Xeroderma Pigmentosum, Complementation Group A (XPA) Antibodies from 24 different suppliers available. Additionally we are shipping XPA Proteins (6) and XPA Kits (3) and many more products for this protein. A total of 160 XPA products are currently listed.
Synonyms:
AI573865, CG6358, DhR14, DhXPA, Dmel\\CG6358, dmXPA, dxpa, EG:EG0007.8, XP1, Xpa, xpac, XPA_DROME, xxpa
list all antibodies Gene Name GeneID UniProt
XPA 7507 P23025
XPA 22590 Q64267
XPA 298074  

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Most Popular Reactivities for anti-XPA (XPA) Antibodies

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anti-Human XPA Antibodies:

anti-Mouse (Murine) XPA Antibodies:

anti-Rat (Rattus) XPA Antibodies:

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Top referenced anti-XPA Antibodies

  1. Human Monoclonal XPA Primary Antibody for IP, WB - ABIN967532 : Aboussekhra, Biggerstaff, Shivji, Vilpo, Moncollin, Podust, Protić, Hübscher, Egly, Wood: Mammalian DNA nucleotide excision repair reconstituted with purified protein components. in Cell 1995 (PubMed)
    Show all 2 references for 967532

  2. Human Monoclonal XPA Primary Antibody for Inhibition, ELISA - ABIN3200998 : Tanaka, Miura, Satokata, Miyamoto, Yoshida, Satoh, Kondo, Yasui, Okayama, Okada: Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. in Nature 1990 (PubMed)
    Show all 2 references for 3200998

  3. Human Polyclonal XPA Primary Antibody for WB - ABIN657757 : Palli, Polidoro, DErrico, Saieva, Guarrera, Calcagnile, Sera, Allione, Gemma, Zanna, Filomena, Testai, Caini, Moretti, Gomez-Miguel, Nesi, Luzzi, Ottini, Masala, Matullo, Dogliotti: Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer. in Mutagenesis 2010 (PubMed)
    Show all 2 references for 657757

  4. Human Monoclonal XPA Primary Antibody for IHC (p), WB - ABIN180381 : Evans, Fellows, Coffer, Wood: Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein. in The EMBO journal 1997 (PubMed)
    Show all 2 references for 180381

  5. Human Polyclonal XPA Primary Antibody for FACS, IHC (p) - ABIN652730 : States, McDuffie, Myrand, McDowell, Cleaver: Distribution of mutations in the human xeroderma pigmentosum group A gene and their relationships to the functional regions of the DNA damage recognition protein. in Human mutation 1998 (PubMed)

More Antibodies against XPA Interaction Partners

Human Xeroderma Pigmentosum, Complementation Group A (XPA) interaction partners

  1. These results illustrate that EZH2 (show EZH2 Antibodies) may promote carcinogenesis and cancer development of nasopharyngeal carcinoma by transcriptional repression of XPA gene and inactivation of nucleotide excision repair pathway.

  2. SNP rs10817938 in promoter region associated with poor prognosis of oral squamous cell carcinoma in Chinese Han population

  3. We showed that loss of HERC2 function leads to the accumulation of XPA and BRCA1 in the patient's fibroblasts and generates decreased sensitivity to apoptosis and increased level of DNA repair

  4. Accumulating evidence suggests that XPA and the helicase activity of transcription factor IIH (TFIIH (show GTF2H1 Antibodies)) cooperate to verify abnormalities in damaged DNA chemistry. (Review)

  5. XPA is a key scaffold protein (show HOMER1 Antibodies) for human nucleotide excision repair. (Review)

  6. XPA reduction increased cell viability of a bladder cancer cell line RT4, while XPA re-expression decreased the cell viability of RT4 cells. Study suggests that downregulated XPA may promote carcinogenesis of bladder cancer via impairment of DNA repair.

  7. The risk of esophageal squamous cell carcinoma associated with XPA rs-1800975 was determined. A high ESCC risk was found in subjects who carried the homozygous minor allele of XPA, especially in smokers, those in adobe houses, drinkers of salt tea, or those with a family history of cancer. Variant genotypes of both XPA and XPC (show XPC Antibodies) in combination showed an increased risk towards ESCC.

  8. The role of conformational selection in the molecular recognition of the wild type and mutants XPA67-80 peptides by ERCC1 (show ERCC1 Antibodies) has been described.

  9. We discovered four new XP-A patients and a novel XPA mutation resulting in two diverse patient alleles.

  10. a specific XPA genotype is associated with mild phenotype in Xeroderma Pigmentosum in United Kingdom immigrants from India, Pakistan, and Afghanistan

Mouse (Murine) Xeroderma Pigmentosum, Complementation Group A (XPA) interaction partners

  1. The authors' results suggest that lack of the DNA repair factor XPA may delay neurobehavioral recovery after TBI

  2. Oxidized glycerophosphocholines play a pivotal role in the photosensitivity associated with the deficiency of XPA.

  3. The tissue-specific effect of Xpa deficiency represents a novel finding; it suggests that tissue-to-tissue variation in CAG repeat (show CELF3 Antibodies) instability arises, in part, by different underlying mechanisms.

  4. The circadian oscillation of XPA is achieved both by regulation of transcription by the core circadian clock proteins including cryptochrome and by regulation at the posttranslational level by the HERC2 ubiquitin ligase.

  5. The Xpa/p53 (show TP53 Antibodies)+/- mouse model is an excellent candidate for a future replacement of the chronic mouse bioassay for certain classes of chemicals.

  6. Xeroderma pigmentosum group A (XPA) gene-deficient mice cannot repair UV-induced DNA damage and easily develop skin cancers by UV irradiation. UVB-induced local and systemic immunosuppression was greatly enhanced in the (-/-) mice.

  7. Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice

  8. XPA (-/-), SCF (show KITLG Antibodies)-Tg mice did not develop skin cancers after repeated exposures to UVB for 30 wk at a total dose of 72 J per cm(2)

  9. Xpa-/- keratinocytes (complete nucleotide excision repair deficiency) show a rapid depletion of DNA replicating S-phase cells, a transient increase in quiescent S-phase cells (not replicating DNA), followed by massive apoptosis.

  10. The human carcinogen phenacetin acts as a weak genotoxic agent in an in vivo mouse model system in an Xpa deficient model.

XPA Antigen Profile

Antigen Summary

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with XPA

  • Xeroderma pigmentosum group A-like (Xpac) antibody
  • xeroderma pigmentosum, complementation group A (XPA) antibody
  • xeroderma pigmentosum, complementation group A (Xpa) antibody
  • xeroderma pigmentosum, complementation group A (xpa) antibody
  • AI573865 antibody
  • CG6358 antibody
  • DhR14 antibody
  • DhXPA antibody
  • Dmel\\CG6358 antibody
  • dmXPA antibody
  • dxpa antibody
  • EG:EG0007.8 antibody
  • XP1 antibody
  • Xpa antibody
  • xpac antibody
  • XPA_DROME antibody
  • xxpa antibody

Protein level used designations for XPA

CG6358-PA , Xpac-PA , xeroderma pigmentosum group A-like , DNA repair protein complementing XP-A cells , excision repair-controlling , xeroderma pigmentosum group A-complementing protein , DNA repair protein complementing XP-A cells homolog , xeroderma pigmentosum group A-complementing protein homolog , xpacch protein , xpacx1 protein

GENE ID SPECIES
31357 Drosophila melanogaster
7507 Homo sapiens
22590 Mus musculus
395659 Gallus gallus
298074 Rattus norvegicus
397790 Xenopus laevis
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