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Browse our anti-XRCC1 (XRCC1) Antibodies

Full name:
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 Antibodies (XRCC1)
On www.antibodies-online.com are 116 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) Antibodies from 20 different suppliers available. Additionally we are shipping XRCC1 Proteins (6) and XRCC1 Kits (3) and many more products for this protein. A total of 132 XRCC1 products are currently listed.
Synonyms:
MGC80909, RCC, Xrcc-1, XRCC1
list all antibodies Gene Name GeneID UniProt
XRCC1 7515 P18887
XRCC1 22594 Q60596
XRCC1 84495 Q9ESZ0

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All available anti-XRCC1 Antibodies

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Top referenced anti-XRCC1 Antibodies

  1. Human Monoclonal XRCC1 Primary Antibody for IHC (fro), IHC (p) - ABIN264445 : Caldecott, Aoufouchi, Johnson, Shall: XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. in Nucleic acids research 1997 (PubMed)
    Show all 8 references for ABIN264445

  2. Human Monoclonal XRCC1 Primary Antibody for IHC (p), IP - ABIN180349 : Cappelli, Taylor, Cevasco, Abbondandolo, Caldecott, Frosina: Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for ABIN180349

  3. Human Polyclonal XRCC1 Primary Antibody for FACS, IF - ABIN651735 : Lamerdin, Montgomery, Stilwagen, Scheidecker, Tebbs, Brookman, Thompson, Carrano: Genomic sequence comparison of the human and mouse XRCC1 DNA repair gene regions. in Genomics 1995 (PubMed)
    Show all 2 references for ABIN651735

More Antibodies against XRCC1 Interaction Partners

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) interaction partners

  1. frequency of the minor allele corresponding to the Trp (show TBPL1 Antibodies) allele of XRCC1Arg194Trp was higher in Asian populations than in African and Caucasian populations

  2. the study indicates that the XRCC1 locus could be a potential candidate contributing to the pathogenesis of schizophrenia.

  3. This meta-analysis suggested that the XRCC1 Arg194Trp polymorphism may be associated with efficacy of platinum-based chemotherapy.

  4. XRCC1 SNPs are associated with acute coronary syndromes in patients from Pakistan.

  5. Our results suggested that decreased XRCC1 expression levels might be associated with the increased risk of therapeutic IR-related acute side effects in patients with breast cancer.

  6. suggested that DNA-PK and PARP (show COL11A2 Antibodies)-dependent recruitment of XRCC1 is necessary to effectively protect, repair, and restart stalled replication forks, providing new insight into how genomic stability is preserved

  7. We have characterized the nuclear localization signal (NLS (show ALDH1A2 Antibodies)) of XRCC1 structurally using X-ray crystallography and functionally using fluorescence imaging.

  8. Our results suggest an increased risk for CRC (show CALR Antibodies) in individuals with XRCC1 Arg194Trp polymorphism suggesting BER repair pathway modulates the risk of developing colorectal cancer in the Kashmiri population.

  9. The results suggest that the RAD51 (show RAD51 Antibodies) G135C and XRCC1 Arg399Gln polymorphisms could be biomarkers of susceptibility for ovarian carcinoma development. Further larger case-control study is needed to confirm our findings

  10. findings showed that the rs25487 and rs1799782 polymorphisms of XRCC1 may contribute to an individual's susceptibility to CBP (show CREBBP Antibodies) and may be used as valid biomarkers

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) interaction partners

  1. We have characterized the nuclear localization signal (NLS (show ALDH1A2 Antibodies)) of XRCC1 structurally using X-ray crystallography and functionally using fluorescence imaging.

  2. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (show OGG1 Antibodies), Neil1 (show NEIL1 Antibodies), Mutyh (show MUTYH Antibodies) and Xrcc1 in the brain of adult offspring.

  3. In cells with DNA base damage, PAR (show AFG3L2 Antibodies) serves to recruit XRCC1 that in turn binds and recruits pol beta (show POLB Antibodies), the primary DNA polymerase (show POLB Antibodies) of the base excision repair pathway.

  4. Lig4 (show LIG4 Antibodies) and XRCC1 double-deficient cells switch as efficiently as Lig4 (show LIG4 Antibodies)-deficient cells, clearly indicating that XRCC1 is dispensable for A-EJ in CH12F3 cells during class switch recombination

  5. findings firmly demonstrate that XRCC1 is not a requisite factor for A-EJ of chromosomal DSBs and raise the possibility that DNA ligase 1 (Lig1 (show LIG1 Antibodies)) may contribute more to A-EJ than previously considered

  6. Data support a role for XRCC1 in microhomology-mediated joining, and imply that AID-induced single-strand breaks in Igh variable and switch regions become substrates simultaneously for BER and mutagenesis pathways.

  7. Results indicates that XRCC1 haploinsufficiency has little effect on chronological longevity and many key biological markers of aging, but may adversely affect normal animal development or increase disease susceptibility to a relevant genotoxic exposure.

  8. data reveal that the critical biological role of Lig3 (show LIG3 Antibodies) is to maintain mtDNA integrity and not Xrcc1-dependent DNA repair

  9. results establish a role for Lig3 (show LIG3 Antibodies) in mitochondria, but distinguish it from its interacting protein Xrcc1

  10. poly(ADP-ribose) polymerase-1 (show PARP1 Antibodies) and XRCC1/DNA ligase III (show LIG3 Antibodies) utilize an alternative route for DNA double-strand breaks rejoining

XRCC1 Antigen Profile

Antigen Summary

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Alternative names and synonyms associated with XRCC1

  • X-ray repair complementing defective repair in Chinese hamster cells 1 (xrcc1) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 1 (Xrcc1) antibody
  • MGC80909 antibody
  • RCC antibody
  • Xrcc-1 antibody
  • XRCC1 antibody

Protein level used designations for XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1 , X-ray repair cross complementing protein 1 , DNA repair protein XRCC1-like , DNA repair protein XRCC1 , X-ray repair cross-complementing protein 1 , X-ray-repair, complementing defective, repair in Chinese hamster , x-ray repair cross-complementing group 1 protein

GENE ID SPECIES
446884 Xenopus laevis
456094 Pan troglodytes
476447 Canis lupus familiaris
616905 Bos taurus
711457 Macaca mulatta
100380033 Xenopus (Silurana) tropicalis
100390129 Callithrix jacchus
100458994 Pongo abelii
100469866 Ailuropoda melanoleuca
100519604 Sus scrofa
100580597 Nomascus leucogenys
7515 Homo sapiens
22594 Mus musculus
84495 Rattus norvegicus
100689414 Cricetulus griseus
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