Browse our anti-XRCC1 (XRCC1) Antibodies

Full name:
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 Antibodies (XRCC1)
On www.antibodies-online.com are 126 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) Antibodies from 23 different suppliers available. Additionally we are shipping XRCC1 Proteins (6) and XRCC1 Kits (3) and many more products for this protein. A total of 142 XRCC1 products are currently listed.
Synonyms:
MGC80909, RCC, Xrcc-1, XRCC1
list all antibodies Gene Name GeneID UniProt
XRCC1 7515 P18887
XRCC1 22594 Q60596
XRCC1 84495 Q9ESZ0

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Most Popular Reactivities for anti-XRCC1 (XRCC1) Antibodies

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anti-Human XRCC1 Antibodies:

anti-Mouse (Murine) XRCC1 Antibodies:

anti-Rat (Rattus) XRCC1 Antibodies:

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Top referenced anti-XRCC1 Antibodies

  1. Human Monoclonal XRCC1 Primary Antibody for IHC (fro), IHC (p) - ABIN264445 : Caldecott, Aoufouchi, Johnson, Shall: XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. in Nucleic acids research 1997 (PubMed)
    Show all 8 references for 264445

  2. Human Polyclonal XRCC1 Primary Antibody for ICC, IF - ABIN151964 : Iles, Rulten, El-Khamisy, Caldecott: APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks. in Molecular and cellular biology 2007 (PubMed)
    Show all 3 references for 151964

  3. Human Polyclonal XRCC1 Primary Antibody for FACS, IF - ABIN651735 : Lamerdin, Montgomery, Stilwagen, Scheidecker, Tebbs, Brookman, Thompson, Carrano: Genomic sequence comparison of the human and mouse XRCC1 DNA repair gene regions. in Genomics 1995 (PubMed)
    Show all 2 references for 651735

More Antibodies against XRCC1 Interaction Partners

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) interaction partners

  1. XRCC1 Arg194 allele is a predicting factor for renal cell carcinoma (show MOK Antibodies).

  2. this updated and cumulative meta-analysis indicated that XRCC1 Arg194Trp polymorphism was associated with increased risk for glioma

  3. Results show that some polymorphic variants in XRCC1 and OGG1 (show OGG1 Antibodies) are associated with increased DNA damage in Alzheimer's Disease.

  4. The interaction of OGG1 (show OGG1 Antibodies) and XRCC1 DNA repair polymorphisms and arsenic exposure enhances telomeric DNA damage.

  5. either PARP1 (show PARP1 Antibodies) or PARP2 (show PARP2 Antibodies) are sufficient for near-normal XRCC1 recruitment at oxidative single-strand breaks

  6. contribution of microhomology-mediated end joining (MMEJ) to DNA double-strand break repair in the genome is affected by radiation exposure via enhancement of the formation of MMEJ-proficient XRCC1 complex

  7. Trp (show TBPL1 Antibodies) allele of codon 194 XRCC1 is a potential risk factor for breast cancer in Kurdish ethnicity. Furthermore, effect of this polymorphism on clinical and histological features of breast cancer was significant

  8. This study suggests that the genetic variant of XRCC1 rs25487 may contribute to the etiology of ischemic stroke.

  9. Individuals carrying theGSTP1 Ile-Ile or XRCC1399 Arg-Arg genotypes showed greater DNA damage than observed for other alleles.

  10. The current meta-analysis demonstrates that the XRCC1 Arg399Gln polymorphism confers susceptibility to autoimmune diseases in Asians and Caucasians and, in particular, shows that XRCC1 Arg399Gln polymorphism is associated with rheumatoid arthritis.

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) interaction partners

  1. data establish the importance of XRCC1 protein complexes for normal neurological function and identify PARP1 (show PARP1 Antibodies) as a therapeutic target in DNA strand break repair-defective disease

  2. We have characterized the nuclear localization signal (NLS (show ALDH1A2 Antibodies)) of XRCC1 structurally using X-ray crystallography and functionally using fluorescence imaging.

  3. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (show OGG1 Antibodies), Neil1 (show NEIL1 Antibodies), Mutyh (show MUTYH Antibodies) and Xrcc1 in the brain of adult offspring.

  4. In cells with DNA base damage, PAR (show AFG3L2 Antibodies) serves to recruit XRCC1 that in turn binds and recruits pol beta (show POLB Antibodies), the primary DNA polymerase (show POLB Antibodies) of the base excision repair pathway.

  5. Lig4 (show LIG4 Antibodies) and XRCC1 double-deficient cells switch as efficiently as Lig4 (show LIG4 Antibodies)-deficient cells, clearly indicating that XRCC1 is dispensable for A-EJ in CH12F3 cells during class switch recombination

  6. findings firmly demonstrate that XRCC1 is not a requisite factor for A-EJ of chromosomal DSBs and raise the possibility that DNA ligase 1 (Lig1 (show LIG1 Antibodies)) may contribute more to A-EJ than previously considered

  7. Data support a role for XRCC1 in microhomology-mediated joining, and imply that AID-induced single-strand breaks in Igh variable and switch regions become substrates simultaneously for BER and mutagenesis pathways.

  8. Results indicates that XRCC1 haploinsufficiency has little effect on chronological longevity and many key biological markers of aging, but may adversely affect normal animal development or increase disease susceptibility to a relevant genotoxic exposure.

  9. data reveal that the critical biological role of Lig3 (show LIG3 Antibodies) is to maintain mtDNA integrity and not Xrcc1-dependent DNA repair

  10. results establish a role for Lig3 (show LIG3 Antibodies) in mitochondria, but distinguish it from its interacting protein Xrcc1

XRCC1 Antigen Profile

Antigen Summary

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Alternative names and synonyms associated with XRCC1

  • X-ray repair complementing defective repair in Chinese hamster cells 1 (xrcc1) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 1 (Xrcc1) antibody
  • MGC80909 antibody
  • RCC antibody
  • Xrcc-1 antibody
  • XRCC1 antibody

Protein level used designations for XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1 , X-ray repair cross complementing protein 1 , DNA repair protein XRCC1-like , DNA repair protein XRCC1 , X-ray repair cross-complementing protein 1 , X-ray-repair, complementing defective, repair in Chinese hamster , x-ray repair cross-complementing group 1 protein

GENE ID SPECIES
446884 Xenopus laevis
456094 Pan troglodytes
476447 Canis lupus familiaris
616905 Bos taurus
711457 Macaca mulatta
100380033 Xenopus (Silurana) tropicalis
100390129 Callithrix jacchus
100458994 Pongo abelii
100469866 Ailuropoda melanoleuca
100519604 Sus scrofa
100580597 Nomascus leucogenys
7515 Homo sapiens
22594 Mus musculus
84495 Rattus norvegicus
100689414 Cricetulus griseus
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