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Browse our anti-SPRY1 (SPRY1) Antibodies

Full name:
anti-Sprouty Homolog 1, Antagonist of FGF Signaling (Drosophila) Antibodies (SPRY1)
On are 34 Sprouty Homolog 1, Antagonist of FGF Signaling (Drosophila) (SPRY1) Antibodies from 13 different suppliers available. Additionally we are shipping SPRY1 Proteins (12) and SPRY1 Kits (1) and many more products for this protein. A total of 53 SPRY1 products are currently listed.
hSPRY1, LOC100223875, sprouty1, SPRY1
list all antibodies Gene Name GeneID UniProt
SPRY1 294981  
SPRY1 24063 Q9QXV9
SPRY1 10252 O43609

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anti-Rat (Rattus) SPRY1 Antibodies:

anti-Mouse (Murine) SPRY1 Antibodies:

anti-Human SPRY1 Antibodies:

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Top referenced anti-SPRY1 Antibodies

  1. Human Monoclonal SPRY1 Primary Antibody for IHC (p), ELISA - ABIN564437 : Moghaddam, Amini, Wei, Pourgholami, Morris: Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines. in Journal of oncology 2012 (PubMed)
    Show all 2 references for ABIN564437

  2. Human Polyclonal SPRY1 Primary Antibody for ELISA, WB - ABIN564436 : Mekkawy, De Bock, Lin, Morris, Wang, Pourgholami: Novel protein interactors of urokinase-type plasminogen activator receptor. in Biochemical and biophysical research communications 2010 (PubMed)

  3. Human Polyclonal SPRY1 Primary Antibody for ELISA, IHC - ABIN4355747 : Hanafusa, Torii, Yasunaga, Matsumoto, Nishida: Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty. in The Journal of biological chemistry 2004 (PubMed)

  4. Human Polyclonal SPRY1 Primary Antibody for EIA, IHC (p) - ABIN452690 : Schaaf, Hamdi, Zwijnenburg, Lakeman, Geerts, Versteeg, Kool: Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene. in Cancer research 2010 (PubMed)

More Antibodies against SPRY1 Interaction Partners

Mouse (Murine) Sprouty Homolog 1, Antagonist of FGF Signaling (Drosophila) (SPRY1) interaction partners

  1. Here, we present a novel mouse model of pheochromocytoma consisting of double-heterozygous mice for Pten (show PTEN Antibodies) and Sprouty1 (Spry1), which leads to pheochromocytomas that appear at earlier onset and grow at a higher rate than those from Pten (show PTEN Antibodies)+/- mice.

  2. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  3. Sprouty gain of function disrupts lens cellular processes and growth by restricting receptor tyrosine kinase (show ERBB3 Antibodies) signaling.

  4. In vivo analysis of thyroid glands from Spry1 knockout mice reveals that Spry1 induces a senescence-associated secretory phenotype via activation of the NFkappaB pathway.

  5. showed that hSpry1 overexpression prevents VEGF secretion

  6. Spry1 and Spry2 (show SPRY2 Antibodies) coordination is required for normal development of the external genitalia in mice

  7. conjunctival epithelial Spry1 and Spry2 (show SPRY2 Antibodies) redundantly promote eyelid closure.

  8. Findings demonstrate that Pokemon (show ZBTB7A Antibodies) suppresses Sprouty1 expression through a miR (show MLXIP Antibodies)-21-mediated mechanism, affecting the growth and proliferation of liver cancer cells.

  9. ISG15 mRNA expression and IFN-dependent (show SPRY2 Antibodies)antiviral (show SPRY4 Antibodies)responses are enhanced in Spry1,2,4 triple knock-out mouse embryonic fibroblasts, consistent with negative feedback regulatory roles for Spry proteins in IFN-mediated signal (show IGF2BP3 Antibodies)ing.

  10. When Spry1 and Spry2 (show SPRY2 Antibodies) loss-of-function occurs in the context of heterozygosity for a null allele of the tumor suppressor gene Pten (show PTEN Antibodies), there is a striking increase in prostatic intraepithelial neoplasia and evidence of neoplastic invasion.

Human Sprouty Homolog 1, Antagonist of FGF Signaling (Drosophila) (SPRY1) interaction partners

  1. Spry1 plays a selective role in at least a subset of triple-negative breast cancer to promote the malignant phenotype via enhancing EGF (show EGF Antibodies)-mediated mesenchymal phenotype.

  2. Suppression of SPRY1 by age-associated methylation inhibits the replenishment of the muscle stem cell pool.

  3. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  4. There is an inverse correlation between the expression of Spry1 and growth, proliferation, invasion and migration of ovarian cancer cells.

  5. A random population of LNCaP prostate cancer cells comprises a heterogeneous group of cells with different androgen-deprivation sensitivities and potential for invasiveness; expression levels of 2 genes known to be regulated by miR (show MLXIP Antibodies)-21, an androgen-regulated microRNA, SPRY1 and JAG1 (show JAG1 Antibodies) were lower in an androgen insensitive clone, than an androgen sensitive clone.

  6. The Spry1 acts as a sensor of mitogenic activity that not only attenuates RTK signaling but also induces a cellular senescence response to avoid uncontrolled proliferation.

  7. Spry1 and Spry4 (show SPRY4 Antibodies) have opposing roles in VSMC phenotypic modulation, and Spry1 maintains the VSMC differentiation phenotype in vitro in part through an Akt (show AKT1 Antibodies)/FoxO (show FOXO3 Antibodies)/myocardin (show MYOCD Antibodies) pathway.

  8. Re-expression of SPRY1, a repressed target of BCL11B (show BCL11B Antibodies), limits the transformation capacity of Ewing sarcoma cells.

  9. miR (show MLXIP Antibodies)-21 promotes robust fibrogenic EMT (show ITK Antibodies) of EMCs, in part by directly targeting PDCD4 (show PDCD4 Antibodies) and SPRY1.

  10. Feedback regulations of miR (show MLXIP Antibodies)-21 and MAPKs via Pdcd4 (show PDCD4 Antibodies) and Spry1 are involved in arsenite-induced cell malignant transformation.

SPRY1 Antigen Profile

Antigen Summary

May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

Alternative names and synonyms associated with SPRY1

  • sprouty homolog 1, antagonist of FGF signaling (Drosophila) (Spry1) antibody
  • sprouty homolog 1, antagonist of FGF signaling (Drosophila) (SPRY1) antibody
  • sprouty homolog 1, antagonist of FGF signaling (LOC100223875) antibody
  • sprouty homolog 1 (Drosophila) (Spry1) antibody
  • hSPRY1 antibody
  • LOC100223875 antibody
  • sprouty1 antibody
  • SPRY1 antibody

Protein level used designations for SPRY1

protein sprouty homolog 1 , sprouty homolog 1, antagonist of FGF signaling (Drosophila) , sprouty homolog 1, antagonist of FGF signaling , inhibitor of receptor tyrosine kinases , sprouty 1 , spry-1 , sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling) , sprouty 1 protein

294981 Rattus norvegicus
461476 Pan troglodytes
483838 Canis lupus familiaris
100223875 Taeniopygia guttata
100593469 Nomascus leucogenys
24063 Mus musculus
10252 Homo sapiens
507095 Bos taurus
395583 Gallus gallus
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