SPRY1 antibody (AA 1-110)

Catalog No. ABIN564437

There are 2+ publications for this product available. The Mouse Monoclonal anti-SPRY1 antibody is suitable to detect SPRY1 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for SPRY1 antibody (AA 1-110) (ABIN564437)

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPRY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3H4

Product Details anti-SPRY1 Antibody

Binding Specificity: AA 1-110

Purpose: Mouse monoclonal antibody raised against a partial recombinant SPRY1.

Sequence: MDPQNQHGSG SSLVVIQQPS LDSRQRLDYE REIQPTAILS LDQIKAIRGS NEYTEGPSVV KRPAPRTAPR QEKHERTHEI IPINVNNNYE HRHTSHLGHA VLPSNARGPI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SPRY1 (NP_005832, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SPRY1 antibody (ABIN564437)

Mekkawy, Pourgholami, Morris: "Human Sprouty1 suppresses growth, migration, and invasion in human breast cancer cells." in: Tumour biology, Vol. 35, Issue 5, pp. 5037-48, (2014) (PubMed).

Moghaddam, Amini, Wei, Pourgholami, Morris: "Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines." in: Journal of oncology, Vol. 2012, pp. 373826, (2012) (PubMed).

Target Details for SPRY1

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Alternative Name: SPRY1

Background: Full Gene Name: sprouty homolog 1, antagonist of FGF signaling (Drosophila)
Synonyms: hSPRY1

Gene ID: 10252

NCBI Accession: NM_005841

Pathways: EGFR Signaling Pathway, EGFR Downregulation