SPRY1 antibody (N-Term)

Catalog No. ABIN2784216

This Rabbit Polyclonal antibody specifically detects SPRY1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SPRY1 antibody (N-Term) (ABIN2784216)

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPRY1 Antibody

Binding Specificity: N-Term

Sequence: PTAILSLDQI KAIRGSNEYT EGPSVVKRPA PRTAPRQEKH ERTHEIIPIN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SPRY1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPRY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 319 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPRY1

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Alternative Name: SPRY1

Background: SPRY1 belongs to the sprouty family. It contains 1 SPR (sprouty) domain. SPRY1 may function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Alias Symbols: hSPRY1
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-1, KRTAP10-9, KRTAP10-7, LCE2D, LCE1B, HEXIM2, KRTAP4-2, R3HDM2, SPRY2, CREB5, OTX1, MEOX2, MDFI, HOXA1, BAG3, SOCS4, GEMIN4, YY1, STAT3, KPNA2, HRG, GRB2, CBL, LAT, MAP4K1, PLCG1, CBLB, ELAVL1, SH3KBP1,
Protein Size: 319

Molecular Weight: 35 kDa

Gene ID: 10252

NCBI Accession: NM_005841, NP_005832

UniProt: O43609

Pathways: EGFR Signaling Pathway, EGFR Downregulation