SPRY1 antibody (N-Term)

Catalog No. ABIN2784216

Product Details anti-SPRY1 Antibody

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rabbit, Dog, Horse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRY1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PTAILSLDQI KAIRGSNEYT EGPSVVKRPA PRTAPRQEKH ERTHEIIPIN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SPRY1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPRY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 319 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPRY1

Target: SPRY1 (Sprouty Homolog 1, Antagonist of FGF Signaling (SPRY1))

Alternative Name: SPRY1 (SPRY1 Products)

Synonyms: hSPRY1 antibody, SPRY1 antibody, LOC100223875 antibody, hspry1 antibody, xspry1 antibody, sprouty antibody, sprouty1 antibody, sprouty-1 antibody, Xtsprouty1 antibody, spry1a antibody, spry1b antibody, sprouty RTK signaling antagonist 1 antibody, sprouty RTK signaling antagonist 1 L homeolog antibody, sprouty RTK signaling antagonist 1 S homeolog antibody, sprouty homolog 1 (Drosophila) antibody, SPRY1 antibody, Spry1 antibody, spry1 antibody, spry1.L antibody, spry1.S antibody

Background: SPRY1 belongs to the sprouty family. It contains 1 SPR (sprouty) domain. SPRY1 may function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Alias Symbols: hSPRY1
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-1, KRTAP10-9, KRTAP10-7, LCE2D, LCE1B, HEXIM2, KRTAP4-2, R3HDM2, SPRY2, CREB5, OTX1, MEOX2, MDFI, HOXA1, BAG3, SOCS4, GEMIN4, YY1, STAT3, KPNA2, HRG, GRB2, CBL, LAT, MAP4K1, PLCG1, CBLB, ELAVL1, SH3KBP1,
Protein Size: 319

Molecular Weight: 35 kDa

Gene ID: 10252

NCBI Accession: NM_005841, NP_005832

UniProt: O43609

Pathways: EGFR Signaling Pathway, EGFR Downregulation