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Browse our anti-NR4A1 (NR4A1) Antibodies

Full name:
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 Antibodies (NR4A1)
On are 157 Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) Antibodies from 22 different suppliers available. Additionally we are shipping NR4A1 Proteins (7) and NR4A1 Kits (4) and many more products for this protein. A total of 182 NR4A1 products are currently listed.
Gfrp, GFRP1, Hbr-1, Hbr1, Hmr, N10, NAK-1, Ngfi-b, NGFIB, NP10, Nur77, TIS1, TR3
list all antibodies Gene Name GeneID UniProt
NR4A1 3164 P22736
NR4A1 15370 P12813
NR4A1 79240 P22829

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anti-Human NR4A1 Antibodies:

anti-Mouse (Murine) NR4A1 Antibodies:

anti-Rat (Rattus) NR4A1 Antibodies:

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Top referenced anti-NR4A1 Antibodies

  1. Mouse (Murine) Monoclonal NR4A1 Primary Antibody for WB - ABIN967395 : Davis, Hazel, Chen, Blenis, Lau: Functional domains and phosphorylation of the orphan receptor Nur77. in Molecular endocrinology (Baltimore, Md.) 1993 (PubMed)
    Show all 5 references for ABIN967395

  2. Human Polyclonal NR4A1 Primary Antibody for EIA - ABIN358306 : Lu, Suzuki, Yoshikawa, Murakami, Miki, Moriya, Bassett, Rainey, Hayashi, Sasano: Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders. in The Journal of clinical endocrinology and metabolism 2004 (PubMed)
    Show all 3 references for ABIN358306

  3. Human Polyclonal NR4A1 Primary Antibody for ELISA, WB - ABIN334451 : Kiss, Oskolás, Tóth, Bouillet, Tóth, Fülöp, Scholtz, Ledent, Fésüs, Szondy: Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77. in European journal of immunology 2006 (PubMed)

  4. Cow (Bovine) Polyclonal NR4A1 Primary Antibody for IHC, WB - ABIN2782269 : Smith, Luk, Newton, Roberts, Sturm, Muscat: Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against NR4A1 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Mutagenesis of residues lining the identified interaction site on Bcl-B (show BCL2L10 Antibodies) negated the interaction with Nur77 protein in cells and prevented Nur77-mediated modulation of apoptosis and autophagy

  2. NR4A1 regulates beta1-integrin expression and beta1-integrin-dependent migration of breast cancer cells, and this is accompanied by decreased expression of beta3-integrin (show ITGB3 Antibodies).

  3. Data indicate that N-myc downstream regulated gene 1 (NDRG1 (show NDRG1 Antibodies)) competitively bind to glycogen synthase kinase 3beta (GSK-3beta (show GSK3b Antibodies)) and orphan nuclear receptor (Nur77) to prevent beta-catenin (show CTNNB1 Antibodies) degradation.

  4. analysis of amino acid fragments required by TR3/Nur77 for its functions in angiogenesis

  5. The results demonstrate that Nur77 is induced by oxLDL via the p38 MAPK (show MAPK14 Antibodies) signaling pathway, which is involved in the regulation of cell survival. Nur77 enhanced cell survival via suppressing apoptosis, without affecting cell proliferation of activated macrophages, which may be beneficial in patients with atherosclerosis.

  6. NR4As regulate gene transcription primarily through interaction with distal enhancers that are co-enriched for NR4A1 and ETS transcription factor (show FEV Antibodies) motifs

  7. miR (show MLXIP Antibodies)-124 to be downregulated in instances of medulloblastoma in which Nur77 is upregulated, resulting in a proliferative state that abets cancer progression.

  8. ApoA-IV (show APOA4 Antibodies) colocalizes with NR4A1, which suppresses G6Pase (show G6PC Antibodies) and PEPCK (show PEPCK Antibodies) gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.

  9. NR4A1 is a key factor in multiple diseases, such as arthritis, inflammation, cancer and cardiovascular diseases.

  10. Identified Nur77/Nor1 (show NR4A3 Antibodies) as novel regulators of thrombomodulin (show THBD Antibodies) expression and function in vascular endothelial cells.

Cow (Bovine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Identify the orphan nuclear receptor NR4A1 as a potential early response gene in FGF2 signaling and regulation of sprouty in bovine ovarian granulosa cells.

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Nur77 modulates the inflammatory state of macrophages by decreasing inflammatory gene expression, inhibits the collagen content of the extracellular matrix of macrophages, and reduces phagocytosis by macrophages.

  2. Detailed knowledge on the role of Nur77 in maintaining cardiomyocyte Ca(2 (show CA2 Antibodies)+) homeostasis and the dual role Nur77 plays in cardiac remodelling will aid in developing personalized therapies against heart failure

  3. NR4A1 functions as a master transcription factor for the development of this novel thymus-specific macrophage subset.

  4. Identified Nur77/Nor1 (show NR4A3 Antibodies) as novel regulators of thrombomodulin (show THBD Antibodies) expression and function in vascular endothelial cells.

  5. In both mouse colitis models inflammation was increased in Nur77-/- mice.Overexpression of Nur77 in lipopolysaccharide activated RAW macrophages up-regulated IL-10 and downregulated TNFalpha, MIF-1 and MCP-1 mRNA expression through NFkappaB repression.

  6. Nr4a1 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.

  7. Data show that transcription factor Nr4a1 expression in myeloid cells limits experimental autoimmune encephalomyelitis (EAE) severity.

  8. Nur77 is a critical negative regulator of Ang II (show AGT Antibodies)-induced VSMC proliferation, migration, and phenotypic switching via the downregulation of beta-catenin (show CTNNB1 Antibodies) activity

  9. Mechanistically, NFATc1 (show NFATC1 Antibodies) induces Nur77 expression at late stage of osteoclast differentiation; in turn, Nur77 transcriptionally up-regulates E3 ubiquitin ligase (show MUL1 Antibodies) Cbl-b, which triggers NFATc1 (show NFATC1 Antibodies) protein degradation.

  10. Nr4a1 induction is dependent on ERK1/2 (show MAPK1/3 Antibodies) and that MKP-1 (show DUSP1 Antibodies) negatively regulates this induction.

NR4A1 Antigen Profile

Antigen Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NR4A1

  • nuclear receptor subfamily 4, group A, member 1 (NR4A1) antibody
  • nuclear receptor subfamily 4, group A, member 1 (Nr4a1) antibody
  • Gfrp antibody
  • GFRP1 antibody
  • Hbr-1 antibody
  • Hbr1 antibody
  • Hmr antibody
  • N10 antibody
  • NAK-1 antibody
  • Ngfi-b antibody
  • NGFIB antibody
  • NP10 antibody
  • Nur77 antibody
  • TIS1 antibody
  • TR3 antibody

Protein level used designations for NR4A1

ST-59 , TR3 orphan receptor , early response protein NAK1 , growth factor-inducible nuclear protein N10 , hormone receptor , nerve growth factor IB nuclear receptor variant 1 , nuclear hormone receptor NUR/77 , nuclear receptor subfamily 4 group A member 1 , orphan nuclear receptor HMR , orphan nuclear receptor TR3 , steroid receptor TR3 , testicular receptor 3 , orphan nuclear receptor NGFI-B , nuclear protein N10 , Orphan nuclear receptor HMR , immediate early gene transcription factor NGFI-B , nerve growth factor induced protein I-B , nerve growth factor-induced protein I-B

3164 Homo sapiens
403897 Canis lupus familiaris
528390 Bos taurus
15370 Mus musculus
79240 Rattus norvegicus
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