Browse our anti-NR4A1 (NR4A1) Antibodies

Full name:
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 Antibodies (NR4A1)
On are 199 Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) Antibodies from 25 different suppliers available. Additionally we are shipping NR4A1 Kits (7) and NR4A1 Proteins (7) and many more products for this protein. A total of 226 NR4A1 products are currently listed.
Gfrp, GFRP1, Hbr-1, Hbr1, Hmr, N10, NAK-1, Ngfi-b, NGFIB, NP10, Nur77, TIS1, TR3
list all antibodies Gene Name GeneID UniProt
NR4A1 3164 P22736
NR4A1 15370 P12813
NR4A1 79240 P22829

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anti-Human NR4A1 Antibodies:

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Top referenced anti-NR4A1 Antibodies

  1. Human Polyclonal NR4A1 Primary Antibody for ChIP, ICC - ABIN252681 : Nakai, Kartha, Sakurai, Toback, DeGroot: A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily. in Molecular endocrinology (Baltimore, Md.) 1991 (PubMed)
    Show all 12 references for 252681

  2. Mouse (Murine) Monoclonal NR4A1 Primary Antibody for WB - ABIN967395 : Davis, Hazel, Chen, Blenis, Lau: Functional domains and phosphorylation of the orphan receptor Nur77. in Molecular endocrinology (Baltimore, Md.) 1993 (PubMed)
    Show all 5 references for 967395

  3. Human Polyclonal NR4A1 Primary Antibody for EIA - ABIN358306 : Lu, Suzuki, Yoshikawa, Murakami, Miki, Moriya, Bassett, Rainey, Hayashi, Sasano: Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders. in The Journal of clinical endocrinology and metabolism 2004 (PubMed)
    Show all 3 references for 358306

  4. Cow (Bovine) Polyclonal NR4A1 Primary Antibody for IHC, WB - ABIN2777511 : Bian, Chen, Yang, Li, Zhang, Zhang, Wang, Zhao, Zhang, Chen, Zheng, Sun, Wang, Chien, Wu: Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. in Nature communications 2017 (PubMed)
    Show all 2 references for 2777511

  5. Cow (Bovine) Polyclonal NR4A1 Primary Antibody for IHC, WB - ABIN2782269 : Smith, Luk, Newton, Roberts, Sturm, Muscat: Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for 2782269

  6. Human Polyclonal NR4A1 Primary Antibody for ELISA, IHC (p) - ABIN188670 : Kiss, Oskolás, Tóth, Bouillet, Tóth, Fülöp, Scholtz, Ledent, Fésüs, Szondy: Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77. in European journal of immunology 2006 (PubMed)

More Antibodies against NR4A1 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Transcript analysis of four different aggressive lymphoma cell lines overexpressing either NR4A3 (show NR4A3 Antibodies) or NR4A1 revealed that apoptosis was driven similarly by induction of BAK (show BAK1 Antibodies), Puma (show BBC3 Antibodies), BIK (show BIK Antibodies), BIM (show BCL2L11 Antibodies), BID (show BID Antibodies), and Trail. Overall, our results showed that NR4A3 (show NR4A3 Antibodies) possesses robust tumor suppressor functions of similar impact to NR4A1 in aggressive lymphomas

  2. NR4A1 expression is specific to a quiescent subset of T-cells.

  3. we demonstrate that endogenous Nur77 protein expression can serve as a reporter of T-cell receptor and B-cell receptor specific signaling in human peripheral blood mononuclear cells.

  4. we report overexpression of the nuclear receptor NR4A1 in rhabdomyosarcomas that is sufficient to drive high expression of PAX3 (show PAX3 Antibodies)-FOXO1A (show FOXO1 Antibodies)

  5. Study found a marked down-regulated gene expression of the NR4A subfamily (NR4A1, NR4A2 (show NR4A2 Antibodies), and NR4A3 (show NR4A3 Antibodies)) obtained from Parkinson's disease patients, but only a NR4A1 decrease in Alzheimer's disease patients compared to healthy controls. This study reports that the entire NR4A subfamily and not only NR4A2 (show NR4A2 Antibodies) could be systemically involved in Parkinson's disease.

  6. Nur77 overexpression prevented pulmonary artery smooth muscle cells from proliferation and migration; Nur77 is an important mediator of hypoxia-induced pulmonary vascular remodeling in pulmonary hypertension

  7. Data show Kruppel-like factor 12 (KLF12 (show KLF12 Antibodies)) impairs endometrial decidualization by transcriptionally repressing Nur77 protein, and Nur77 overexpression reverses the poor decidual response of endometrial stromal cells (hESCs) in recurrent implantation failure (RIF) patients.

  8. Nur77 decreases ET-1 (show EDN1 Antibodies) expression by suppressing NF-kappaB (show NFKB1 Antibodies) and p38 MAPK (show MAPK14 Antibodies).

  9. NR4A1 is highly expressed in a subset of HGSOC samples from patients that have a worse progression free survival.

  10. Nur77 gene expression levels might involve different autonomy of ACTH (show POMC Antibodies) production between Cushing disease (CD) and subCD.

Cow (Bovine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Identify the orphan nuclear receptor NR4A1 as a potential early response gene in FGF2 signaling and regulation of sprouty in bovine ovarian granulosa cells.

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. current data identify Nr4a1 as regulator of microglia activation and potentially new target for the treatment of inflammatory CNS diseases such as multiple sclerosis.

  2. Celastrol promotes Nur77 migration from the nucleus to mitochondria, where it is ubiquitinated by TRAF2 (show TRAF2 Antibodies). Ubiquitinated Nur77 then interacts with p62/SQSTM1 (show SQSTM1 Antibodies), leading to autophagy of dysfunctional mitochondria and alleviation of inflammation.

  3. New transcript variants encode for NUR77 protein isoforms which are significantly smaller in size due to lack of transactivation domain and a part of DNA binding domain. Western blot analysis using NUR77 specific antibody confirmed the existence of these smaller variants in mouse.

  4. Nur77 deficiency compromises myofiber growth, but not the regenerative capacity of myogenic progenitor cells.

  5. Using Nr4a1 transgenic mice, electrically evoked dopamine release was shown to differ between the striosome and matrix compartments of the corpus striatum in a regionally-distinct manner.

  6. Nur77 was found to be an important modulator in microglia function and attenuated pro-inflammatory mediator production.

  7. this study shows that in NR4A1-/- mice, inflammatory Ly6Chigh monocytes contribute to rapid development of arthritis in a serum transfer-induced arthritis model

  8. Nur77 downregulation triggers pulmonary artery smooth muscle cell proliferation and migration in mice with hypoxic pulmonary hypertension

  9. Our findings may throw light on the function of ApoA4 (show APOA4 Antibodies) in inflammatory responses and acute-phase reactions, as well as the development of SERPINA3 (show SERPINA3 Antibodies) relative diseases.

  10. This study demonstrated that NGFI-B plays a role in controlling correct cerebellar development.

NR4A1 Antigen Profile

Antigen Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NR4A1

  • nuclear receptor subfamily 4, group A, member 1 (NR4A1) antibody
  • nuclear receptor subfamily 4, group A, member 1 (Nr4a1) antibody
  • Gfrp antibody
  • GFRP1 antibody
  • Hbr-1 antibody
  • Hbr1 antibody
  • Hmr antibody
  • N10 antibody
  • NAK-1 antibody
  • Ngfi-b antibody
  • NGFIB antibody
  • NP10 antibody
  • Nur77 antibody
  • TIS1 antibody
  • TR3 antibody

Protein level used designations for NR4A1

ST-59 , TR3 orphan receptor , early response protein NAK1 , growth factor-inducible nuclear protein N10 , hormone receptor , nerve growth factor IB nuclear receptor variant 1 , nuclear hormone receptor NUR/77 , nuclear receptor subfamily 4 group A member 1 , orphan nuclear receptor HMR , orphan nuclear receptor TR3 , steroid receptor TR3 , testicular receptor 3 , orphan nuclear receptor NGFI-B , nuclear protein N10 , Orphan nuclear receptor HMR , immediate early gene transcription factor NGFI-B , nerve growth factor induced protein I-B , nerve growth factor-induced protein I-B

3164 Homo sapiens
403897 Canis lupus familiaris
528390 Bos taurus
15370 Mus musculus
79240 Rattus norvegicus
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