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NR4A1 Products

(Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Categories

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

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Featured NR4A1 Categories

NR4A1 Antibodies

High quality antibodies with extensive validation data.

NR4A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NR4A1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NR4A1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application IHC, WB
Validations
  • (1)
  • (5)
Cat. No. ABIN2777511
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7180055
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN2854866
Quantity 100 μL
Datasheet Datasheet

Recommended NR4A1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958267
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381367
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN2685095
Quantity 1 kit
Datasheet Datasheet

Recommended NR4A1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084690
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132921
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312979
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NR4A1 products

Qin, Gao, Wang, Huang, Peng, Mo, Wang: "Nur77 promotes cigarette smoke‑induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin-1." in: International journal of molecular medicine, Vol. 44, Issue 1, pp. 25-36, (2019) (PubMed).

Li, Yin, Hong, Liu, Jin, Wang, Wang, Tian: "The orphan nuclear receptor NUR77 promotes trophoblast invasion at early pregnancy through paracrine placental growth factor." in: Journal of molecular medicine (Berlin, Germany), Vol. 97, Issue 9, pp. 1359-1373, (2019) (PubMed).

Qi, Guo, Wei, Jin, Wang, Mao: "The involvement of NR4A1 and NR4A2 in the regulation of the luteal function in rats." in: Acta histochemica, Vol. 120, Issue 8, pp. 713-719, (2018) (PubMed).

Imura, Kobayashi, Suzutani, Ichikawa-Tomikawa, Chiba: "Differential expression of a stress-regulated gene Nr4a2 characterizes early- and late-born hippocampal granule cells." in: Hippocampus, (2018) (PubMed).

Bian, Chen, Yang, Li, Zhang, Zhang, Wang, Zhao, Zhang, Chen, Zheng, Sun, Wang, Chien, Wu: "Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation." in: Nature communications, Vol. 8, pp. 14420, (2017) (PubMed).

Geradts, Groth, Wu, Jin: "Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS)." in: Breast cancer research and treatment, Vol. 157, Issue 3, pp. 447-59, (2017) (PubMed).

Hedrick, Lee, Safe: "The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists." in: Molecular carcinogenesis, Vol. 56, Issue 9, pp. 2066-2075, (2017) (PubMed).

Li, Zhao, Xu, Shan, Hu, Qiu, Xu: "The autism-related gene SNRPN regulates cortical and spine development via controlling nuclear receptor Nr4a1." in: Scientific reports, Vol. 6, pp. 29878, (2016) (PubMed).

Reynolds, Hancock, Ray, Kener, Draney, Garland, Hardman, Bikman, Tessem: "β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion." in: American journal of physiology. Endocrinology and metabolism, Vol. 311, Issue 1, pp. E186-201, (2016) (PubMed).

Nowakowski, Pollen, Sandoval-Espinosa, Kriegstein: "Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." in: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).

Synonyms and alternative names related to NR4A1

nuclear receptor subfamily 4 group A member 1 (NR4A1), nuclear receptor subfamily 4, group A, member 1 (Nr4a1), Gfrp, GFRP1, Hbr-1, Hbr1, HMR, Hmr, N10, NAK-1, NGFI-B, Ngfi-b, NGFIB, NP10, NUR77, nur77, Nur77, TIS1, TR3

Protein level used designations for NR4A1

  • ST-59
  • TR3 orphan receptor
  • early response protein NAK1
  • growth factor-inducible nuclear protein N10
  • hormone receptor
  • nerve growth factor IB nuclear receptor variant 1
  • nuclear hormone receptor NUR/77
  • nuclear receptor subfamily 4 group A member 1
  • orphan nuclear receptor HMR
  • orphan nuclear receptor TR3
  • steroid receptor TR3
  • testicular receptor 3
  • orphan nuclear receptor NGFI-B
  • nuclear protein N10
  • Orphan nuclear receptor HMR
  • immediate early gene transcription factor NGFI-B
  • nerve growth factor induced protein I-B
  • nerve growth factor-induced protein I-B
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