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Browse our NR4A1 Proteins (NR4A1)

Full name:
Nuclear Receptor Subfamily 4, Group A, Member 1 Proteins (NR4A1)
On are 7 Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) Proteins from 4 different suppliers available. Additionally we are shipping NR4A1 Antibodies (158) and NR4A1 Kits (5) and many more products for this protein. A total of 183 NR4A1 products are currently listed.
Gfrp, GFRP1, Hbr-1, Hbr1, Hmr, N10, NAK-1, Ngfi-b, NGFIB, NP10, Nur77, TIS1, TR3
list all proteins Gene Name GeneID UniProt
NR4A1 3164 P22736
NR4A1 15370 P12813
NR4A1 79240 P22829

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NR4A1 Proteins (NR4A1) by Origin

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More Proteins for NR4A1 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Nur77 overexpression prevented pulmonary artery smooth muscle cells from proliferation and migration; Nur77 is an important mediator of hypoxia-induced pulmonary vascular remodeling in pulmonary hypertension

  2. Data show Kruppel-like factor 12 (KLF12 (show KLF12 Proteins)) impairs endometrial decidualization by transcriptionally repressing Nur77 protein, and Nur77 overexpression reverses the poor decidual response of endometrial stromal cells (hESCs) in recurrent implantation failure (RIF) patients.

  3. Nur77 decreases ET-1 (show EDN1 Proteins) expression by suppressing NF-kappaB (show NFKB1 Proteins) and p38 MAPK (show MAPK14 Proteins).

  4. NR4A1 is highly expressed in a subset of HGSOC samples from patients that have a worse progression free survival.

  5. Nur77 gene expression levels might involve different autonomy of ACTH (show POMC Proteins) production between Cushing disease (CD) and subCD.

  6. Data show that three TR3 orphan nuclear receptor (TR3) transcript variant messenger RNAs (mRNAs) are expressed in human umbilical vein endothelial cell (HUVEC) and are differentially regulated by vascular endothelial growth factor (VEGF).

  7. Mutagenesis of residues lining the identified interaction site on Bcl-B (show BCL2L10 Proteins) negated the interaction with Nur77 protein in cells and prevented Nur77-mediated modulation of apoptosis and autophagy

  8. NR4A1 regulates beta1-integrin expression and beta1-integrin-dependent migration of breast cancer cells, and this is accompanied by decreased expression of beta3-integrin (show ITGB3 Proteins).

  9. Data indicate that N-myc downstream regulated gene 1 (NDRG1 (show NDRG1 Proteins)) competitively bind to glycogen synthase kinase 3beta (GSK-3beta) and orphan nuclear receptor (Nur77) to prevent beta-catenin (show CTNNB1 Proteins) degradation.

  10. analysis of amino acid fragments required by TR3/Nur77 for its functions in angiogenesis

Cow (Bovine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. Identify the orphan nuclear receptor NR4A1 as a potential early response gene in FGF2 signaling and regulation of sprouty in bovine ovarian granulosa cells.

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) interaction partners

  1. this study shows that in NR4A1-/- mice, inflammatory Ly6Chigh monocytes contribute to rapid development of arthritis in a serum transfer-induced arthritis model

  2. Nur77 downregulation triggers pulmonary artery smooth muscle cell proliferation and migration in mice with hypoxic pulmonary hypertension

  3. Our findings may throw light on the function of ApoA4 (show APOA4 Proteins) in inflammatory responses and acute-phase reactions, as well as the development of SERPINA3 (show SERPINA3 Proteins) relative diseases.

  4. This study demonstrated that NGFI-B plays a role in controlling correct cerebellar development.

  5. Nur77 modulates the inflammatory state of macrophages by decreasing inflammatory gene expression, inhibits the collagen content of the extracellular matrix of macrophages, and reduces phagocytosis by macrophages.

  6. Detailed knowledge on the role of Nur77 in maintaining cardiomyocyte Ca(2 (show CA2 Proteins)+) homeostasis and the dual role Nur77 plays in cardiac remodelling will aid in developing personalized therapies against heart failure

  7. NR4A1 functions as a master transcription factor for the development of this novel thymus-specific macrophage subset.

  8. Identified Nur77/Nor1 (show NR4A3 Proteins) as novel regulators of thrombomodulin (show THBD Proteins) expression and function in vascular endothelial cells.

  9. In both mouse colitis models inflammation was increased in Nur77-/- mice.Overexpression of Nur77 in lipopolysaccharide activated RAW macrophages up-regulated IL-10 and downregulated TNFalpha, MIF-1 and MCP-1 mRNA expression through NFkappaB repression.

  10. Nr4a1 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.

NR4A1 Protein Profile

Protein Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NR4A1

  • nuclear receptor subfamily 4, group A, member 1 (NR4A1)
  • nuclear receptor subfamily 4, group A, member 1 (Nr4a1)
  • Gfrp protein
  • GFRP1 protein
  • Hbr-1 protein
  • Hbr1 protein
  • Hmr protein
  • N10 protein
  • NAK-1 protein
  • Ngfi-b protein
  • NGFIB protein
  • NP10 protein
  • Nur77 protein
  • TIS1 protein
  • TR3 protein

Protein level used designations for NR4A1

ST-59 , TR3 orphan receptor , early response protein NAK1 , growth factor-inducible nuclear protein N10 , hormone receptor , nerve growth factor IB nuclear receptor variant 1 , nuclear hormone receptor NUR/77 , nuclear receptor subfamily 4 group A member 1 , orphan nuclear receptor HMR , orphan nuclear receptor TR3 , steroid receptor TR3 , testicular receptor 3 , orphan nuclear receptor NGFI-B , nuclear protein N10 , Orphan nuclear receptor HMR , immediate early gene transcription factor NGFI-B , nerve growth factor induced protein I-B , nerve growth factor-induced protein I-B

3164 Homo sapiens
403897 Canis lupus familiaris
528390 Bos taurus
15370 Mus musculus
79240 Rattus norvegicus
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