NR4A1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all NR4A1 Proteins
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NR4A1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NAK1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR4A1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- Alternative Name
- Nak1 (NR4A1 Products)
- Synonyms
- GFRP1 Protein, HMR Protein, N10 Protein, NAK-1 Protein, NGFIB Protein, NP10 Protein, NUR77 Protein, TR3 Protein, NGFI-B Protein, Gfrp Protein, Hbr-1 Protein, Hbr1 Protein, Hmr Protein, TIS1 Protein, nur77 Protein, Ngfi-b Protein, Nur77 Protein, nuclear receptor subfamily 4 group A member 1 Protein, nuclear receptor subfamily 4, group A, member 1 Protein, NR4A1 Protein, Nr4a1 Protein
- Background
- This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 64.3 kDa
- NCBI Accession
- NP_002126
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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