Browse our GNA11 Proteins (GNA11)

Full name:
Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) Proteins (GNA11)
On www.antibodies-online.com are 10 Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) Proteins from 5 different suppliers available. Additionally we are shipping GNA11 Antibodies (42) and GNA11 Kits (3) and many more products for this protein. A total of 59 GNA11 products are currently listed.
Synonyms:
Dsk7, E430025L19, G-alpha-11, GNA-11, HHC2, HYPOC2
list all proteins Gene Name GeneID UniProt
GNA11 2767 P29992
GNA11 14672 P21278
GNA11 81662 Q9JID2

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GNA11 Proteins (GNA11) by Origin

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More Proteins for GNA11 Interaction Partners

Human Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) interaction partners

  1. we find iris melanomas to be related genetically to choroidal and ciliary body melanomas, frequently harboring GNAQ (show GNAQ Proteins), GNA11, and EIF1AX (show EIF1AX Proteins) mutations.

  2. GNAQ and GNA11 mutations occur frequently in mucosal melanoma and may be a prognostic factor for MM. Our data implicate that GNAQ/11 may be potential targets for targeted therapy of mucosal melanoma.

  3. CGRP (show S100A12 Proteins) family of receptors displays both ligand- and RAMP-dependent signaling bias among the Galphas (show GNAS Proteins), Galphai, and Galphaq (show GNAQ Proteins)/11 pathways.

  4. The identified GNA11 mutation results in biochemical abnormalities typical for autosomal dominant hypocalcemia. Additional features, including short stature and early intracranial calcifications, cosegregated with the mutation.

  5. In 33 CASR (show CASR Proteins)-negative patients with suspected FHH (show CASR Proteins), Data found two (~6%) with a mutation in AP2S1 (show AP2S1 Proteins) (p.Arg15Leu and p.Arg15His). Family screening confirmed the genotype-phenotype correlations. Data did not identify any pathogenic mutations in GNA11.

  6. Driver mutations are rare in mutational hotspots of BRAF (show BRAF Proteins), NRAS (show NRAS Proteins), KIT, and GNAQ (show GNAQ Proteins)/GNA11 in oral mucosal melanoma.

  7. These findings demonstrate that CaSR (show CASR Proteins)-targeted compounds can rectify signaling disturbances caused by germline and somatic Galpha11 mutations, which respectively lead to calcium disorders and tumorigenesis; and that ADH2 (show ADH1B Proteins)-causing Galpha11 mutations induce non-constitutive alterations in MAPK (show MAPK1 Proteins) signaling.

  8. Mutations in GNA11 gene is associated with malignant uveal melanoma.

  9. extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 and GNAQ (show GNAQ Proteins), genes that encode Galpha (show SUCLG1 Proteins) subunits of heterotrimeric G proteins

  10. Melanomas associated with blue nevi or mimicking cellular blue nevi commonly have GNA11 mutations.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) interaction partners

  1. G protein-coupled receptor Kinase 2 reacts with this protein's signaling homology domain for binding G protein subunits

Pig (Porcine) Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) interaction partners

  1. The phylogenetic trees reveal that porcine Gna11, is evolutionarily close to the human homolog.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) interaction partners

  1. the results have identified 138 and 150 ovarian genes that are up-regulated or down-regulated, respectively, at the end of gestation in a Galphaq (show GNAQ Proteins)/11-dependent fashion.

  2. claudin-3 (show CLDN3 Proteins) and claudin-5 (show CLDN5 Proteins) expression is increased by DHEAS (show SULT2A1 Proteins) and tight junction formation is stimulated via a Gnalpha11-coupled receptor in Sertoli cells

  3. ZIP9/Gna11 interactions mediate the non-classical testosterone signaling cascade in spermatogenic GC-2 cells.

  4. the conditional deletion of Galphaq (show GNAQ Proteins)/11 from granulosa/luteal cells prevents the progesterone withdrawal that occurs at the end of pregnancy and impairs parturition.

  5. Loss of gq/11 genes does not abolish melanopsin (show OPN4 Proteins) phototransduction.

  6. Mediated by lysophosphatidylinositol, Galpha(q (show GNAQ Proteins)/11) is activated in sensory neurons.

  7. Dehydroepiandrosterone sulfate (DHEAS (show SULT2A1 Proteins))-induced signaling is mediated through interaction with a membrane-bound G-protein-coupled receptor (show GPR34 Proteins), since silencing of Gnalpha11 leads to the abolition of the DHEAS (show SULT2A1 Proteins)-induced stimulation of Erk1/2, ATF-1 (show AFT1 Proteins), and CREB (show CREB1 Proteins).

  8. Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase (show MAPK1 Proteins) cascade via the Galpha(q (show GNAQ Proteins)/11)--p63RhoGEF--RhoA (show RHOA Proteins) axis.

  9. Myocytes from the Galpha(q (show GNAQ Proteins)) and/or Galpha (show SUCLG1 Proteins)(11) KO mice displayed genuine alterations in the action potentials, membrane capacitance, membrane currents, and Ca(2 (show CA2 Proteins)+) handling

  10. Report differential expression of protein kinase C isoforms in coronary arteries of diabetic mice lacking Gna11.

GNA11 Protein Profile

Protein Summary

may be involved in mediating second messenger signals from the endothelin receptor in adipocytes

Alternative names and synonyms associated with GNA11

  • guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (GNA11)
  • guanine nucleotide binding protein, alpha 11 (Gna11)
  • guanine nucleotide regulatory protein G11 alpha subunit (gna11)
  • Dsk7 protein
  • E430025L19 protein
  • G-alpha-11 protein
  • GNA-11 protein
  • HHC2 protein
  • HYPOC2 protein

Protein level used designations for GNA11

Guanine nucleotide-binding protein alpha-11 subunit , phospholipase C-activating G-protein , G-protein subunit alpha-11 , g alpha-11 , guanine nucleotide-binding protein G(y) subunit alpha , guanine nucleotide-binding protein subunit alpha-11 , guanine nucleotide-binding protein, Gq class, GNA11 , G-protein subunit GL2 alpha , G alpha-11 , guanine nucleotide binding protein alpha 11 , guanine nucleotide regulatory protein G alpha 11 , guanine nucleotide-binding protein alpha 11 subunit

GENE ID SPECIES
100151748 Meleagris gallopavo
2767 Homo sapiens
281788 Bos taurus
403914 Canis lupus familiaris
733588 Sus scrofa
14672 Mus musculus
81662 Rattus norvegicus
779103 Xenopus laevis
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