Browse our CD44 Proteins (CD44)

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CD44 Proteins (CD44)
On are 35 CD44 Proteins from 12 different suppliers available. Additionally we are shipping CD44 Antibodies (1530) and CD44 Kits (53) and many more products for this protein. A total of 1630 CD44 products are currently listed.
AU023126, AW121933, AW146109, CD44A, CDW44, CSPG8, ECMR-III, HCELL, HERMES, HUTCH-I, IN, LHR, Ly-24, MC56, MDU2, MDU3, METAA, MIC4, Pgp-1, Pgp1, RHAMM
list all proteins Gene Name GeneID UniProt
CD44 12505 P15379
CD44 25406  
CD44 960 P16070

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CD44 Proteins (CD44) by Origin

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Top referenced CD44 Proteins

  1. Human CD44 Protein expressed in Wheat germ - ABIN1348653 : Gebhard, Jain, Nair, Emmons, Argilagos, Koomen, McLaughlin, Hazlehurst: MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. in Molecular cancer therapeutics 2013 (PubMed)
    Show all 2 references for 1348653

  2. Human CD44 Protein expressed in HEK-293 Cells - ABIN2713719 : Zhang, Jia, Wang, Li, Hou, Yin, Wang, He, Lu: A CD44 specific peptide developed by phage display for targeting gastric cancer. in Biotechnology letters 2015 (PubMed)

  3. Human CD44 Protein expressed in HEK-293 Cells - ABIN2180800 : Hanley, Burdick, Konstantopoulos, Sackstein: CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. in Cancer research 2005 (PubMed)

More Proteins for CD44 Interaction Partners

Mouse (Murine) CD44 interaction partners

  1. CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.

  2. CD44V6 is part of a positive-feedback loop with TGFbeta1 (show TGFB1 Proteins)/TGFbetaRI signaling that acts to increase NOX4 (show NOX4 Proteins)/ROS (show ROS1 Proteins) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  3. HAS2 (show HAS2 Proteins)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (show MAPK3 Proteins)/EGR1 (show EGR1 Proteins) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (show TGFB1 Proteins)-stimulated CD44V6/ERK (show EPHB2 Proteins)/EGR1 (show EGR1 Proteins) signaling.

  4. CD44 promotes accumulation of M2 macrophages, extracellular matrix deposition, and wall thickening during arteriovenous fistula maturation.

  5. CD44-expressing Neural Stem Cells are self-renewing and multipotent and they synthesize Hyaluronan that accumulates with aging. CD44-null Neural Stem Cells demonstrate increased proliferation in vitro and in vivo.

  6. CD44 knockout mice are more susceptible to stress-induced anxiety-like behavior than control mice.

  7. CD44 contributes to effective antibacterial defense during S. zooepidemicus infection, thereby limiting the accompanying injury and death.

  8. These studies demonstrate that both endometrial cell and peritoneal mesothelial cell CD44 play a role in the development of early endometriotic lesion.

  9. Targeting CD44 expressing colon cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin.

  10. MGK as hydrophobic moieties and oHA as the target of CD44 receptor.

Pig (Porcine) CD44 interaction partners

  1. Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells

  2. CD44 has a key role in oocyte maturation but not in cumulus expansion.

  3. This study demonstrates that the CD14 (show CD14 Proteins)-negative isolation yields an enhanced cell population SFB (show CEBPB Proteins) that is more potent than MSCP (show SLC25A37 Proteins) as a cell source for cartilage tissue engineering.

  4. CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.

Human CD44 interaction partners

  1. This study indicates that ovarian cancer-derived exosomes transfer CD44 to human peritoneal mesothelial cells, facilitating cancer invasion.

  2. YAP (show YAP1 Proteins) mediates CD44 up-regulation at the transcriptional level, conferring tumor stem cell-like properties in malignant mesothelioma cells, and statin represents a potential therapeutic option against MM by inactivating YAP (show YAP1 Proteins).

  3. This study suggests that CD44 and CD147 (show BSG Proteins) together improve the prognostic efficacy of tumor differentiation; in vitro results further point out that these markers might be determinant of differentiation characteristics, imparting properties of increased self-renewal, migration, and invasion.

  4. Of the 22 single nucleotide polymorphisms studied, the rs8193 polymorphism lying in the micro-RNA binding site of 3'-UTR of CD44 was significantly (P=.0270) associated with RT-induced adverse skin reactions. Generalized multifactor dimensionality reduction analysis showed significant (P=.0107) gene-gene interactions between MAT1A (show MAT1A Proteins) and CD44. Furthermore, an increase in the total number of risk alleles was associated with in

  5. The crystal structure of the lectin and EGF (show EGF Proteins)-like domains of human L-selectin (show SELL Proteins) is solved at 1.9 A resolution.

  6. CD44V6 is part of a positive-feedback loop with TGFbeta1 (show TGFB1 Proteins)/TGFbetaRI signaling that acts to increase NOX4 (show NOX4 Proteins)/ROS (show ROS1 Proteins) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  7. results indicate that the CD44 silencing-induced metabolic shift is mediated by the regulation of c-Src (show SRC Proteins)/Akt (show AKT1 Proteins)/LKB1 (show STK11 Proteins)/AMPKalpha (show GRK4 Proteins)/HIF-1alpha (show HIF1A Proteins) signaling in human breast cancer cells

  8. used a next generation sequencing (NGS) approach. NY-SAR-35 expression induced growth, proliferation, metastasis, and stemness genes, as indicated by the up-regulations of CXCR4 (show CXCR4 Proteins), EpCAM (show EPCAM Proteins), CD133, and CD44, at the mRNA and protein levels

  9. CD44+/24- and ALDH1 (show ALDH1A1 Proteins)-positive rates in primary tumors differed according to intrinsic subtype. ER-positive patients with CD44+/24- tumors had significantly longer disease-free-survival than all other ER-positive patients

  10. CD44 expression showed no significant association with neoadjuvant chemoradiotherapy response in esophageal adenocarcinoma.

Cow (Bovine) CD44 interaction partners

  1. CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Proteins).

  2. release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.

  3. CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro

  4. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Proteins), CD44, and CD62L (show SELL Proteins) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

  5. detection of CD44 in the bovine oviductal epithelium

  6. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR Proteins)-mediated signalling pathways involving Cdc2 (show CDK1 Proteins) and gamma-adducin (show ADD3 Proteins).

  7. The novel finding that TSP-1 (show THBS1 Proteins)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 Proteins) and HyA (show KDM5D Proteins)).

Horse (Equine) CD44 interaction partners

  1. An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.

CD44 Protein Profile

Protein Summary

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Alternative names and synonyms associated with CD44

  • CD44 antigen (Cd44)
  • CD44 antigen-like (LOC100525150)
  • Cd44 molecule (Cd44)
  • CD44 molecule (Indian blood group) (CD44)
  • syndecan 4 (SDC4)
  • AU023126 protein
  • AW121933 protein
  • AW146109 protein
  • CD44A protein
  • CDW44 protein
  • CSPG8 protein
  • ECMR-III protein
  • HCELL protein
  • HERMES protein
  • HUTCH-I protein
  • IN protein
  • LHR protein
  • Ly-24 protein
  • MC56 protein
  • MDU2 protein
  • MDU3 protein
  • METAA protein
  • MIC4 protein
  • Pgp-1 protein
  • Pgp1 protein
  • RHAMM protein

Protein level used designations for CD44 Proteins (CD44)

ECMR-III , GP90 lymphocyte homing/adhesion receptor , HUTCH-I , PGP-I , extracellular matrix receptor III , hermes antigen , hyaluronate receptor , lymphocyte antigen 24 , phagocytic glycoprotein 1 , phagocytic glycoprotein I , CD44 antigen , Cell surface glycoprotein CD44 (hyaluronate binding protein) , PGP-1 , Hermes antigen , cell surface glycoprotein CD44 , chondroitin sulfate proteoglycan 8 , epican , hematopoietic cell E- and L-selectin ligand , heparan sulfate proteoglycan , homing function and Indian blood group system , extracellular matrix receptor-III , CD44-like protein , lymphocyte surface antigen precursor CD44 , syndecan 4 (amphiglycan, ryudocan) , syndecan-4

12505 Mus musculus
100750640 Cricetulus griseus
100525150 Sus scrofa
25406 Rattus norvegicus
960 Homo sapiens
403939 Canis lupus familiaris
101098744 Felis catus
281057 Bos taurus
395666 Gallus gallus
101113884 Ovis aries
100034221 Equus caballus
100301546 Oryctolagus cuniculus
419184 Gallus gallus
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