Browse our anti-EXT2 (EXT2) Antibodies

Full name:
anti-Exostosin 2 Antibodies (EXT2)
On are 2 Exostosin 2 (EXT2) Antibodies from 2 different suppliers available. A total of 2 EXT2 products are currently listed.
AI893565, SOTV
list all antibodies Gene Name GeneID UniProt
Anti-Mouse EXT2 EXT2 14043 P70428
EXT2 2132 Q93063

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anti-Human EXT2 Antibodies:

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Mouse (Murine) Exostosin 2 (EXT2) interaction partners

  1. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  2. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  3. The EXT2 gene encodes an essential component of the glycosyltransferase (show GTDC2 Antibodies) complex required for biosynthesis of heparan sulfate, which may eventually modulate the signaling involved in bone formation

  4. EXT2 peaks during early postnatal period in the cerebrum and around birth in the cerebellum. EXT2 was localized primarily in the neuroepithelial cells surrounding the lateral ventricles, the mesencephalic vesicle, and the fourth ventricle.

  5. NDST1 competes with EXT1 for binding to EXT2.

Human Exostosin 2 (EXT2) interaction partners

  1. Germline EXT2 mutation is associated with chondrosarcoma.

  2. The mutation results in deletion of exon 5 in the mRNA, producing a frameshift that leads to a premature termination codon. The present study extends the mutational spectrum of EXT2.

  3. Authors identified two homozygous mutations p.Met87Arg and p.Arg95 Cys (show DNAJC5 Antibodies) in exostosin 2, EXT2, a ubiquitously expressed gene that encodes a glycosyltransferase (show GTDC2 Antibodies). In patient cells, diminished expression and function was observed.

  4. We report the discovery of a non-sense mutation in EXT2 in an 11 (show DCAF7 Antibodies)-y-old boy diagnosed with multiple osteochondroma.

  5. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  6. EXT2 gene might not have a major role in the development of type 2 diabetes in the Chinese population.

  7. EXT2 mutation is associated with multiple osteochondromatosis.

  8. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  9. loss of function of EXT2 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS Antibodies) secretion capacity and development.

  10. Analysis of microsatellite polymorphic markers in the 11p region harboring the EXT2 gene did not reveal any loss of heterozygosity

EXT2 Antigen Profile

Antigen Summary

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with EXT2

  • exostoses (multiple) 2 (Ext2) antibody
  • exostosin 2 (EXT2) antibody
  • exostosin glycosyltransferase 2 (EXT2) antibody
  • AI893565 antibody
  • SOTV antibody

Protein level used designations for anti-Exostosin 2 (EXT2) Antibodies

exostosin-2 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 2 homolog , HS-POL , HS-polymerase , exostoses (multiple) 2 , glucuronyl/N-acetylglucosaminyl transferase , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 2 , putative tumor suppressor protein EXT2

14043 Mus musculus
281151 Bos taurus
2132 Homo sapiens
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