Browse our GCNT2 Proteins (GCNT2)

Full name:
Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) Proteins (GCNT2)
On www.antibodies-online.com are 7 Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) Proteins from 3 different suppliers available. Additionally we are shipping GCNT2 Antibodies (55) and many more products for this protein. A total of 66 GCNT2 products are currently listed.
Synonyms:
5330430K10Rik, bA360O19.2, bA421M1.1, CCAT, CTRCT13, GCNT2C, GCNT5, IGNT, IGnTA, IGnTB, IGnTC, II, NACGT1, NAGCT1, ULG3
list all proteins Gene Name GeneID UniProt
GCNT2 14538  
Rat GCNT2 GCNT2 306860  
GCNT2 2651 Q8N0V5 , Q06430 , Q8NFS9

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GCNT2 Proteins (GCNT2) by Origin

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More Proteins for GCNT2 Interaction Partners

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. These data clearly suggest that GCNT2 functions in vivo together with beta3GnT2 to determine poly-N-acetyllactosamine (PLN (show PLN Proteins)) levels in olfactory neurons by regulating beta1,6-branches that promote PLN (show PLN Proteins) extension.

  2. conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I (show GCNT1 Proteins) form a network of disulfide bonds and include a thiol that affects enzyme activity

  3. molecular cloning and analysis of expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase (show GCNT1 Proteins)

  4. Leukocyte core2GlcNAc transferase is required for biosynthesis of functional L-selectin (show SELL Proteins) ligands in inflamed venules of mouse cremaster muscle.

Human Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. miR (show MLXIP Proteins)-199a/b-5p regulates GCNT2 and I antigen expression in colon cancer cells undergoing EMT (show ITK Proteins)

  2. This study reports a novel insertion/deletion mutation at the GCNT2 locus that is responsible for congenital cataracts in a large consanguineous family.

  3. GCNT2 expression is closely associated with invasive potential of prostate cancer.

  4. Hypomethylation of the GCNT2 variant 2 reflected lymph node metastasis of colorectal cancer in the tumor and normal tissues.

  5. An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group (show DARC Proteins)

  6. Results show involvement of GCNT2 in EMT (show ITK Proteins) and TGF-beta (show TGFB1 Proteins) signaling, and further glycosylation modification of E-cadherin (show CDH1 Proteins) by GCNT2, are the underlying integrative mechanisms for breast cancer metastasis.

  7. In the family with the "ii" blood group a novel GCNT2 mutation was found in the cataract patients.

  8. A nonsense mutation in the GCNT2 gene isoforms is associated with autosomal recessive congenital cataract in four distantly related Arab families from Israel.

  9. role of C/EBPalpha (show CEBPA Proteins) in the induction of the IGnTC gene as well as in I antigen expression

GCNT2 Protein Profile

Protein Summary

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with GCNT2

  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Gcnt2)
  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2)
  • 5330430K10Rik protein
  • bA360O19.2 protein
  • bA421M1.1 protein
  • CCAT protein
  • CTRCT13 protein
  • GCNT2C protein
  • GCNT5 protein
  • IGNT protein
  • IGnTA protein
  • IGnTB protein
  • IGnTC protein
  • II protein
  • NACGT1 protein
  • NAGCT1 protein
  • ULG3 protein

Protein level used designations for GCNT2

I-branching enzyme , N-acetylglucosaminyltransferase , N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase , beta-1,6-N-acetylglucosaminyltransferase , glucosaminyltransferase, I-branching enzyme , large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase , I-branching beta-1,6-acetylglucosaminyltransferase , I beta-1,6-N-acetylglucosaminyltransferase , Ii blood group , beta-1,6-N-acetylglucosaminyltransferase 2

GENE ID SPECIES
14538 Mus musculus
306860 Rattus norvegicus
2651 Homo sapiens
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