Browse our GCNT2 Proteins (GCNT2)

Full name:
Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) Proteins (GCNT2)
On are 7 Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) Proteins from 3 different suppliers available. Additionally we are shipping GCNT2 Antibodies (55) and many more products for this protein. A total of 66 GCNT2 products are currently listed.
5330430K10Rik, bA360O19.2, bA421M1.1, CCAT, CTRCT13, GCNT2C, GCNT5, IGNT, IGnTA, IGnTB, IGnTC, II, NACGT1, NAGCT1, ULG3
list all proteins Gene Name GeneID UniProt
GCNT2 14538  
Rat GCNT2 GCNT2 306860  
GCNT2 2651 Q8N0V5 , Q06430 , Q8NFS9

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GCNT2 Proteins (GCNT2) by Origin

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More Proteins for GCNT2 Interaction Partners

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. These data clearly suggest that GCNT2 functions in vivo together with beta3GnT2 to determine poly-N-acetyllactosamine (PLN (show PLN Proteins)) levels in olfactory neurons by regulating beta1,6-branches that promote PLN (show PLN Proteins) extension.

  2. conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I (show GCNT1 Proteins) form a network of disulfide bonds and include a thiol that affects enzyme activity

  3. molecular cloning and analysis of expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase (show GCNT1 Proteins)

  4. Leukocyte core2GlcNAc transferase is required for biosynthesis of functional L-selectin (show SELL Proteins) ligands in inflamed venules of mouse cremaster muscle.

Human Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. miR (show MLXIP Proteins)-199a/b-5p regulates GCNT2 and I antigen expression in colon cancer cells undergoing EMT (show ITK Proteins)

  2. This study reports a novel insertion/deletion mutation at the GCNT2 locus that is responsible for congenital cataracts in a large consanguineous family.

  3. GCNT2 expression is closely associated with invasive potential of prostate cancer.

  4. Hypomethylation of the GCNT2 variant 2 reflected lymph node metastasis of colorectal cancer in the tumor and normal tissues.

  5. An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group (show DARC Proteins)

  6. Results show involvement of GCNT2 in EMT (show ITK Proteins) and TGF-beta (show TGFB1 Proteins) signaling, and further glycosylation modification of E-cadherin (show CDH1 Proteins) by GCNT2, are the underlying integrative mechanisms for breast cancer metastasis.

  7. In the family with the "ii" blood group a novel GCNT2 mutation was found in the cataract patients.

  8. A nonsense mutation in the GCNT2 gene isoforms is associated with autosomal recessive congenital cataract in four distantly related Arab families from Israel.

  9. role of C/EBPalpha (show CEBPA Proteins) in the induction of the IGnTC gene as well as in I antigen expression

GCNT2 Protein Profile

Protein Summary

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with GCNT2

  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Gcnt2)
  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2)
  • 5330430K10Rik protein
  • bA360O19.2 protein
  • bA421M1.1 protein
  • CCAT protein
  • CTRCT13 protein
  • GCNT2C protein
  • GCNT5 protein
  • IGNT protein
  • IGnTA protein
  • IGnTB protein
  • IGnTC protein
  • II protein
  • NACGT1 protein
  • NAGCT1 protein
  • ULG3 protein

Protein level used designations for GCNT2

I-branching enzyme , N-acetylglucosaminyltransferase , N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase , beta-1,6-N-acetylglucosaminyltransferase , glucosaminyltransferase, I-branching enzyme , large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase , I-branching beta-1,6-acetylglucosaminyltransferase , I beta-1,6-N-acetylglucosaminyltransferase , Ii blood group , beta-1,6-N-acetylglucosaminyltransferase 2

14538 Mus musculus
306860 Rattus norvegicus
2651 Homo sapiens
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