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GCH1 Proteins

(GTP Cyclohydrolase 1 (GCH1))
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described\; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008].

Active filters:

  • Target: GCH1
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN1354910
GCH1 Protein (AA 1-250) (GST tag) GCH1 · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$447.26 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7888973
GCH1 Protein (AA 1-250) GCH1 · Protein Human Escherichia coli (E. coli)
$1,961.14 View price
  • 500 μg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN3080453
GCH1 Protein (AA 1-250) (Strep Tag) GCH1 · Protein Human Cell-free protein synthesis (CFPS)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
starts at $19,692.86 View price
  • 250 μg
  • 500 μg
Delivery in 55 to 67 Business Days Shipping to: United States
ABIN7422661
GCH1 Protein (AA 16-250) (His tag) GCH1 · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • PC (Positive Control: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • Imm (Immunogen: Listed application)
$721.75 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN1608986
GCH1 Protein (AA 1-225) (His tag) GCH1 · Protein Rainbow Trout Yeast
  • ELISA (ELISA: Listed application)
$2,742.41 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1608968
GCH1 Protein (AA 1-80) (His tag) GCH1 · Protein Velvet bean (Mucuna pruriens) Yeast
  • ELISA (ELISA: Listed application)
$2,261.80 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7584429
GCH1 Protein (AA 12-241) (His tag) GCH1 · Protein Rat Yeast
  • ELISA (ELISA: Listed application)
$1,253.51 View price
  • 100 μg
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1461743
GCH1 Protein (AA 1-80) (His tag) GCH1 · Protein Euglena gracilis Yeast
  • ELISA (ELISA: Listed application)
$2,261.80 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1459043
GCH1 Protein (AA 1-236) (His tag) GCH1 · Protein Chicken Yeast
  • ELISA (ELISA: Listed application)
$2,779.68 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN2750202
GCH1 Protein GCH1 · Protein Human, Rat, Mouse Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • PC (Positive Control: Listed application)
$338.46 View price
  • 5 applications
Delivery in 1 to 3 Business Days Shipping to: United States
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1354910
$447.26
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7888973
$1,961.14
Plus shipping costs $50.00, if applicable $20.00 dry ice
500 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
Grade
custom-made
Origin
Human
Host
Cell-free protein synthesis (CFPS)
Protein Type
Recombinant
Purity
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3080453
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to: United States
Delivery in 55 to 67 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • PC (Positive Control: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • Imm (Immunogen: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 97 %
Catalog No. ABIN7422661
$721.75
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Rainbow Trout
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1608986
$2,742.41
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Velvet bean (Mucuna pruriens)
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1608968
$2,261.80
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Rat
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7584429
$1,253.51
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Euglena gracilis
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1461743
$2,261.80
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Chicken
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1459043
$2,779.68
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human, Rat, Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN2750202
$338.46
Plus shipping costs $50.00
5 applications
Shipping to: United States
Delivery in 1 to 3 Business Days

Latest Publications for our GCH1 Proteins

Widder, Chen, Li, Dikalov, Thöny, Hatakeyama, Harrison: "Regulation of tetrahydrobiopterin biosynthesis by shear stress." in: Circulation research, Vol. 101, Issue 8, pp. 830-8, (2007) (PubMed).

Aliases for GCH1 Proteins

GTP cyclohydrolase 1 (GCH1) Proteins
GTP cyclohydrolase 1 (Gch1) Proteins
GTP cyclohydrolase 1 (gch1) Proteins
GTP cyclohydrolase 1 (Weevi_1190) Proteins
GTP cyclohydrolase 1 (Halhy_0838) Proteins
GTP cyclohydrolase 1 (Sinme_1220) Proteins
GTP cyclohydrolase 1 (Sphch_1077) Proteins
GTP cyclohydrolase 1-like (LOC100136794) Proteins
DYT5 Proteins
DYT5a Proteins
DYT14 Proteins
GCH Proteins
Gch Proteins
gch1a Proteins
GTP-CH Proteins
GTP-CH-1 Proteins
GTPCH Proteins
GTPCH1 Proteins
HPABH4B Proteins
MGC89622 Proteins
wu:fc16b10 Proteins
zgc:195269 Proteins
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