Browse our ITIH2 Proteins (ITIH2)

On are 5 Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2) Proteins from 4 different suppliers available. Additionally we are shipping ITIH2 Antibodies (25) and ITIH2 Kits (8) and many more products for this protein. A total of 43 ITIH2 products are currently listed.
AI747202, H2P, Intin2, ITI-HC2, Itih-2, SHAP
list all proteins Gene Name GeneID UniProt
ITIH2 16425 Q61703
ITIH2 3698 P19823
ITIH2 512164  

ITIH2 Proteins (ITIH2) by Origin

More Proteins for ITIH2 Interaction Partners

Human Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2) interaction partners

  1. Data suggest that Mg2 (show MUC7 Proteins)+ or Mn2+ (but not Ca2 (show CA2 Proteins)+) induce a conformational change in inter-alpha-inhibitor (ITIH1 (show ITIH1 Proteins) and ITIH2) and a bikunin (show AMBP Proteins)/chondroitin sulfate-dependent increase in thermodynamic stability; bikunin (show AMBP Proteins) binds adjacent to the two heavy chains.

  2. Human inter-alpha-inhibitor is a substrate for factor XIIIa (show F13A1 Proteins) and tissue transglutaminase (show TGM2 Proteins).

  3. TSG-6 (show TNFAIP6 Proteins) acts as cofactor and catalyst in the production of IalphaI heavy chain x hyaluronan complexes

  4. Leukocytes infiltrated to the synovium were strongly positive for hyaluronic acid, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in inflammation.

  5. Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor.

  6. serum-derived hyaluronan-associated protein (show ITIH1 Proteins)-hyaluronan complex has a role in progression of ovarian cancer

ITIH2 Protein Profile

Protein Summary

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987

Alternative names and synonyms associated with ITIH2

  • inter-alpha trypsin inhibitor, heavy chain 2 (Itih2)
  • inter-alpha-trypsin inhibitor heavy chain 2 (ITIH2)
  • inter-alpha-trypsin inhibitor heavy chain 2 (Itih2)
  • AI747202 protein
  • H2P protein
  • Intin2 protein
  • ITI-HC2 protein
  • Itih-2 protein
  • SHAP protein

Protein level used designations for ITIH2

ITI heavy chain H2 , ITI-HC2 , inter-alpha-inhibitor heavy chain 2 , inter-alpha-trypsin inhibitor heavy chain H2 , inter-alpha (globulin) inhibitor H2 , inter-alpha (globulin) inhibitor, H2 polypeptide , inter-alpha-trypsin inhibitor complex component II , serum-derived hyaluronan-associated protein , inter-alpha globulin inhibitor H2 polypeptide , inter-alpha-inhibitor heavy-chain H2 , Inter-alpha-inhibitor heavy chain 2

16425 Mus musculus
3698 Homo sapiens
512164 Bos taurus
396937 Sus scrofa
101837243 Mesocricetus auratus
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