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Human ESM1 ELISA Kit for Sandwich ELISA - ABIN856973
Nirala, Perumal, Gohil: Glycated serum albumin stimulates expression of endothelial cell specific molecule-1 in human umbilical vein endothelial cells: Implication in diabetes mediated endothelial dysfunction. in Diabetes & vascular disease research 2015
Show all 3 references for ABIN856973
Mouse (Murine) ESM1 ELISA Kit for Sandwich ELISA - ABIN1889318
Lassalle, Molet, Janin, Heyden, Tavernier, Fiers, Devos, Tonnel: ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines. in The Journal of biological chemistry 1996
Results reveal a novel pathway for endocan in the control of tumor growth, which involves inflammatory cells of the innate immunity.
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
This study shows endocan can elicit severe inflammatory responses and inhibiting endocan release offers a potential strategy for treating sepsis.
endocan is normally present in the mouse brain and prior vascular perfusion with FITC may provide a useful tool for identify newly forming blood vessels.
Mouse endocan serum level was measured at a median of 0.96 ng/mL and 1.08 ng/mL in 129Sv mice and C57bl6, respectively.
A paracrine vasoregulatory pathway mediated by endothelial cell-derived ET-1 (show EDN1 ELISA Kits) acting on the vascular smooth muscle ET(A (show EDNRA ELISA Kits)) receptor.
Results suggest that endocan (ESM-1)is preferentially expressed in tumor endothelium in vivo and that its expression is regulated by tumor-derived factors.
Dopamine agonist resistance-related ESM1 promotes the angiogenesis and tumor cells growth of prolactinomas, suggesting that ESM1 may be a novel therapeutic target for prolactinomas.
These results suggest human cytomegalovirus infection leads to glioma progression through an upregulation of endocan and the secretion of inflammatory cytokines.
Endocan-expressing microvessel density significantly correlates with the expression of VEGF (show VEGFA ELISA Kits) and VEGFR2 (show KDR ELISA Kits) and is a valuable prognostic factor for survival in human gastric cancer.
Circulating P-selectin (show SELP ELISA Kits) levels were closely associated with endocan levels in obese children and adolescents with non-alcoholic fatty liver disease.
this study shows that endocan may play an important role in the development of connective tissue disease related pulmonary arterial hypertension
The distribution of Gleason score and biochemical failure rate were significantly higher in patients with serum endocan >/=1.8 ng/mL (p = 0.031 and p = 0.047).
endocan plays an anti-carcinogenic role in gastric cancer development and progression and might serve as a prognostic biomarker as well as a potential therapeutic target for gastric cancer.
High ESM1 expression is associated with Meningiomas and Gliomas.
Serum and urinary endocan concentrations are significantly elevated in patients with bladder cancer.
Subclinical hypothyroidism is associated with increased levels of serum endocan, dimethylarginine, and TGF-beta (show TGFB1 ELISA Kits), which are new markers for endothelial dysfunction.
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
endothelial cell-specific molecule 1
, ESM-1 secretory protein
, pineal specific PG25 protein