Browse our anti-RHBDF2 (RHBDF2) Antibodies

Full name:
anti-Rhomboid 5 Homolog 2 (Drosophila) Antibodies (RHBDF2)
On are 21 Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) Antibodies from 8 different suppliers available. Additionally we are shipping RHBDF2 Proteins (6) and many more products for this protein. A total of 32 RHBDF2 products are currently listed.
4732465I17Rik, RHBDL5, Rhbdl6, TOC
list all antibodies Gene Name GeneID UniProt
RHBDF2 79651 Q6PJF5
RHBDF2 217344 Q80WQ6

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anti-Human RHBDF2 Antibodies:

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Human Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) interaction partners

  1. results explain how loss of the amino terminus in iRhom1 (show RHBDF1 Antibodies) and iRhom2 impairs TNF (show TNF Antibodies) signaling, despite enhancing ADAM17 (show ADAM17 Antibodies) activity

  2. Tylosis with oesophageal cancer-associated mutations in iRHOM2 cause an increase in the maturation and activity of ADAM17 (show ADAM17 Antibodies) in epidermal keratinocytes.

  3. Our analyses suggest that these DNA methylation (show HELLS Antibodies) changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network.

  4. RHBDF2 and CYGB (show CYGB Antibodies) may play distinctive roles in ovarian cancer and could be added to the growing roster of chromosome 17 genes implicated in this disease.

  5. The distribution of RHBDF2 in tylotic skin is altered in comparison with that in normal skin.

Mouse (Murine) Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) interaction partners

  1. baseline expression of genes acting within the NRF2 (show NFE2L2 Antibodies) anti-oxidative pathway, followed by gene alterations associated with the integrin receptor aggregation pathway and the FcgammaR-mediated phagocytosis pathway, contribute to accelerated wound healing

  2. the critical role of the transmembrane domains of ADAM17 (show ADAM17 Antibodies) and Rhbdf2 in the regulation of the ADAM17 (show ADAM17 Antibodies) and EGFR (show EGFR Antibodies), and ADAM17 (show ADAM17 Antibodies) and TNFalpha (show TNF Antibodies) signaling pathways, was examined.

  3. this study shows that the iRhom2/ADAM17 (show ADAM17 Antibodies) pathway plays an important role in regulating CSF1R (show CSF1R Antibodies) expression in the myeloid cell compartment at steady state, and in modulating development of monocytes/macrophages during their repopulation

  4. this study shows that iRhom2-deficient mice were more susceptible to lethal herpes simplex virus type 1 infection, and that iRhom2 is essential for STING activity, as it regulates TRAPbeta (show SSR2 Antibodies)-mediated translocation and EIF3S5 (show EIF3F Antibodies)-mediated deubiquitination of STING

  5. This study identifies iRhom2 as a novel regulator for determination of keratinocyte lineages.

  6. IRhom2 may be a promising therapeutic target for LPS (show TLR4 Antibodies)-induced cardiac injury.

  7. iRhom2 is required for the maturation of TACE (show ADAM17 Antibodies) and hair follicle differentiation.

  8. a principal function of iRhoms1/2 during mouse development is to regulate ADAM17 (show ADAM17 Antibodies)-dependent EGFR (show EGFR Antibodies) signaling

  9. Rhbdf2 mutations increase its protein stability and drive EGFR (show EGFR Antibodies) hyperactivation through enhanced secretion of amphiregulin (show AREG Antibodies).

  10. findings uncover functions for iRhom2 in the regulation of EGFR (show EGFR Antibodies) signaling and in controlling the activation and substrate selectivity of ADAM17 (show ADAM17 Antibodies)-dependent shedding events

RHBDF2 Antigen Profile

Antigen Summary

Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity).

Alternative names and synonyms associated with RHBDF2

  • rhomboid 5 homolog 2 (Drosophila) (RHBDF2) antibody
  • rhomboid 5 homolog 2 (Drosophila) (Rhbdf2) antibody
  • 4732465I17Rik antibody
  • RHBDL5 antibody
  • Rhbdl6 antibody
  • TOC antibody

Protein level used designations for RHBDF2

iRhom2 , inactive rhomboid protein 2 , rhomboid family member 2 , rhomboid veinlet-like protein 5 , rhomboid veinlet-like protein 6 , rhomboid, veinlet-like 6 , rhomboid-like protein 6 , rhomboid-related protein , Rhomboid family member 2 , rhomboid veinlet-like 6

79651 Homo sapiens
217344 Mus musculus
483332 Canis lupus familiaris
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