Browse our anti-WDR35 (WDR35) Antibodies

Full name:
anti-WD Repeat Domain 35 Antibodies (WDR35)
On are 16 WD Repeat Domain 35 (WDR35) Antibodies from 10 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 20 WDR35 products are currently listed.
4930459M12Rik, 4931430C06, CED2, IFT121, mKIAA1336, RGD1564116, Wdr35
list all antibodies Gene Name GeneID UniProt
WDR35 57539 Q9P2L0
WDR35 74682 Q8BND3
WDR35 298876  

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Human WD Repeat Domain 35 (WDR35) interaction partners

  1. Psychomotor development was apparently normal. Molecular analysis in one of the affected individuals identified compound heterozygosity for a nonsense (c.1922T>G, p.(Leu641*)) and missense (c.2522A>T, p.(Asp841Val)) variants in WDR35. We

  2. Splicing variants in WDR35, and possibly in other IFT-A components, underlie a number of Ellis-van Creveld syndrome (show EVC Antibodies) cases by disrupting targeting of both the EvC (show EVC Antibodies) complex and Smoothened (show SMO Antibodies) to cilia.

  3. report on the detection of novel WDR35 mutations in two unrelated cranioectodermal dysplasia patients

  4. A pathogenic WDR35 mutation was identified in a family with a complex clinical presentation that includes significant overlap of the phenotypes described in Sensenbrenner syndrome and the unclassified short-rib polydactyly syndromes.

  5. Through structural modeling, we show that WDR35 has strong homology to the COPI coatamers involved in vesicular trafficking and that short-rib polydactyly mutations affect key structura (show SHH Antibodies)l elements in WDR35.

  6. WDR35 is homologous to TULP4 (show TULP4 Antibodies) (from the Tubby (show TUB Antibodies) superfamily) and has previously been characterized as an intraflagellar transport component, confirming that Sensenbrenner syndrome is a ciliary disorder.

  7. These results indicated that naofen may function as a novel modulator activating caspase-3 (show CASP3 Antibodies), and promoting TNF-alpha (show TNF Antibodies)-stimulated apoptosis.

Mouse (Murine) WD Repeat Domain 35 (WDR35) interaction partners

  1. These results suggest that bupivacaine activates AMPK (show PRKAA1 Antibodies) and p38 MAPK (show MAPK14 Antibodies) via CaMKK (show CAMKK2 Antibodies) in Neuro2a cells, and that the CaMKK (show CAMKK2 Antibodies)/AMPK (show PRKAA1 Antibodies)/p38 MAPK (show MAPK14 Antibodies) pathway is involved in regulating WDR35 expression.

  2. C-Jun (show JUN Antibodies) siRNA did not inhibit the bupivacaine-induced increase in WDR35 mRNA expression.

  3. In a mutation screen for developmental phenotypes, we identified a mutation in Wdr35 as the cause of midgestation lethality, with abnormalities characteristic of defects in the Hedgehog (show SHH Antibodies) signaling pathway.

WDR35 Antigen Profile

Antigen Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.

Alternative names and synonyms associated with WDR35

  • WD repeat domain 35 (WDR35) antibody
  • WD repeat domain 35 (Wdr35) antibody
  • WD repeat domain 35-like (Wdr35l) antibody
  • 4930459M12Rik antibody
  • 4931430C06 antibody
  • CED2 antibody
  • IFT121 antibody
  • mKIAA1336 antibody
  • RGD1564116 antibody
  • Wdr35 antibody

Protein level used designations for WDR35

WD repeat-containing protein 35 , intraflagellar transport protein 121 homolog , naofen

57539 Homo sapiens
74682 Mus musculus
298876 Rattus norvegicus
503018 Rattus norvegicus
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