Browse our anti-HNF1 Homeobox B (HNF1B) Antibodies

Full name:
anti-HNF1 Homeobox B Antibodies (HNF1B)
On www.antibodies-online.com are 122 HNF1 Homeobox B (HNF1B) Antibodies from 22 different suppliers available. Additionally we are shipping HNF1 Homeobox B Kits (31) and HNF1 Homeobox B Proteins (8) and many more products for this protein. A total of 170 HNF1 Homeobox B products are currently listed.
Synonyms:
AI385728, AI987804, chunp6877, FJHN, HNF-1b, HNF-1Beta, hnf1-beta, hnf1b, Hnf1beta, HNF2, HPC11, LF-B3, lfb3, MODY5, mst, Tcf-2, Tcf2, vHNF-1, vHNF1
list all antibodies Gene Name GeneID UniProt
HNF1B 6928 P35680
HNF1B 21410 P27889
HNF1B 25640 P23899

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Top referenced anti-HNF1 Homeobox B Antibodies

  1. Dog (Canine) Monoclonal HNF1B Primary Antibody for IF, WB - ABIN968855 : De Simone, De Magistris, Lazzaro, Gerstner, Monaci, Nicosia, Cortese: LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia. in The EMBO journal 1991 (PubMed)
    Show all 3 references for 968855

  2. Human Polyclonal HNF1B Primary Antibody for ELISA, WB - ABIN334505 : Terasawa, Toyota, Sagae, Ogi, Suzuki, Sonoda, Akino, Maruyama, Nishikawa, Imai, Shinomura, Saito, Tokino: Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines. in British journal of cancer 2006 (PubMed)
    Show all 2 references for 334505

  3. Cow (Bovine) Polyclonal HNF1B Primary Antibody for WB - ABIN2779562 : Wu, Bohn, Ryffel: The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations. in European journal of biochemistry / FEBS 2004 (PubMed)

  4. Human Polyclonal HNF1B Primary Antibody for EIA, WB - ABIN952765 : Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010 (PubMed)

  5. Cow (Bovine) Polyclonal HNF1B Primary Antibody for WB - ABIN2777700 : Hakonarson, Qu, Bradfield, Marchand, Kim, Glessner, Grabs, Casalunovo, Taback, Frackelton, Eckert, Annaiah, Lawson, Otieno, Santa, Shaner, Smith, Onyiah, Skraban, Chiavacci, Robinson, Stanley, Kirsch et al.: A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. ... in Diabetes 2008 (PubMed)

More Antibodies against HNF1 Homeobox B Interaction Partners

Human HNF1 Homeobox B (HNF1B) interaction partners

  1. Results identified HNF1A/B as a good candidates to master the regulation of pancreatic differentiation, which at the protein level loses its expression in malignant ductal cells of the pancreas, suggesting its putative role as tumor suppressor in pancreatic cancer.

  2. Structural anomalies of the biliary system were common in HNF1B mutation carriers.

  3. Study have shown that expression of specific miRNAs depends on HNF1beta function. The impact of HNF1beta deficiency was evidenced at serum level, making HNF1beta-dependent miRNAs potentially applicable in the diagnosis of HNF1B-MODY (show HNF4A Antibodies).

  4. HNF1B mutation was associated with congenital anomalies of the kidney and urinary tract, as well as pancreatic hypoplasia.

  5. Overall 61.2% of clear cell RCC (show XRCC1 Antibodies) and 75% of UC were immunopositive with HNF-1beta in our study. HNF-1beta has a limited utility in differentiating CCC of the genitourinary system from an ovarian primary

  6. Our MRKH families included 43 quads, 26 trios, and 30 duos. Of our MRKH probands, 87/147 (59%) had MRKH type 1 and 60/147 (41%) had type 2 with additional anomalies. CONCLUSION(S): Although the prevalence of WNT4 (show WNT4 Antibodies), HNF1B, and LHX1 (show LHX1 Antibodies) point mutations is low in people with MRKH, the prevalence of CNVs was approximately 19%.

  7. HNF-1beta suppression in tubular epithelial cells (TECs) is a crucial event for the dedifferentiation of TECs, and the upregulation of HNF-1beta in TECs has a potential to restore the dedifferentiated TECs into their normal state, leading to the attenuation of renal fibrosis

  8. importin-beta (show KPNB1 Antibodies) is involved in the maintenance of the mitotic retention of HNF1beta, suggesting a functional link between the nuclear import system and the mitotic localization/translocation of bookmarking factors.

  9. rs11651755 in HNF1B was found to be associated with endometriosis in this case-control study.

  10. Because HNF1B-related disease is a heterozygous condition, calcineurin (show PPP3CA Antibodies) inhibitors used to prevent rejection may induce reduced expression of the nonmutated allele of HNF1B leading to a superimposed defect of HNF-1beta transcriptional activity.

Xenopus laevis HNF1 Homeobox B (HNF1B) interaction partners

  1. Overexpression of two mutant HNF1B derivatives resulted in distinct phenotypes reflected by either a reduction or an enlargement of pronephros size.

  2. nephrogenic transcription factors (osr1 (show OSR1 Antibodies), osr2, hnf1b, lhx1 (show LHX1 Antibodies), pax8 (show PAX8 Antibodies))play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A (show INHBA Antibodies), retinoic acid

  3. CHOP (GADD153 (show DDIT3 Antibodies)) is an inhibitor of Wnt (show WNT2 Antibodies)/TCF (show HNF4A Antibodies) signals

Mouse (Murine) HNF1 Homeobox B (HNF1B) interaction partners

  1. These results demonstrated the crucial role of Hnf1b and Foxa3 (show FOXA3 Antibodies) in hepatogenesis in vitro and provided a valuable tool for the efficient differentiation of HLCs (show HLCS Antibodies) from ES cells.

  2. HNF-1beta Regulates MicroRNA-200 Expression through a Long Noncoding RNA

  3. TNFalpha (show TNF Antibodies) regulates uromodulin (show UMOD Antibodies) expression in a homeostatic setting, but the impact of TNFalpha (show TNF Antibodies) on uromodulin (show UMOD Antibodies) during kidney injury is superseded by other factors that could inhibit HNF1beta-mediated expression of uromodulin (show UMOD Antibodies).

  4. Hypoxia induced early up-regulation of Hnf-1beta from 1 to 24 hours, independently of the hypoxia-inducible factor Hif-1alpha (show HIF1A Antibodies).

  5. Zyxin (show ZYX Antibodies) regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1beta.

  6. HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch (show NOTCH1 Antibodies) signalling components and Irx1 (show IRX1 Antibodies)/2.

  7. identification of Hnf1b as a target of miR (show MLXIP Antibodies)-802-dependent silencing; show that short hairpin RNA (shRNA)-mediated reduction of Hnf1b in liver causes glucose intolerance, impairs insulin (show INS Antibodies) signalling and promotes hepatic gluconeogenesis

  8. Hnf1b and Pax2 (show PAX2 Antibodies) operate to control kidney morphogenesis and ureter differentiation.

  9. Overexpression of HNF1beta resulted in accelerated cell proliferation with the protein level up-regulation of plasminogen (show PLG Antibodies) and plasmin (show PLG Antibodies), a converted active form of plasminogen (show PLG Antibodies), which play a pivotal role in liver regeneration inducing hepatocyte proliferation.

  10. Data indicate that HNF1alpha (show HNF1A Antibodies) is a more potent activator of AFM (show AFM Antibodies) promoter than is HNF1beta.

Zebrafish HNF1 Homeobox B (HNF1B) interaction partners

  1. Data show that hnf1ba generates a permissive domain for Wnt (show WNT2 Antibodies) signaling activity in the foregut endoderm

  2. Knockdown of pk1a led to decreased expression of vhnf1, a homeodomain gene previously shown to be involved in biliary development and in kidney cyst formation; forced expression of vhnf1 mRNA led to rescue of the pk1a morphant phenotype

  3. Data show that vhnf1 functions in two ways to subdivide the zebrafish caudal (show CAD Antibodies) hindbrain domain (r4-r7) into individual rhombomeres.

  4. Zebrafish tcf2 gene, composed of 9 exons, was mapped to linkage group LG15.

  5. vhnf1 acts largely independently of val to repress the rhombomere 4 'hox (show MSH2 Antibodies) code' posterior to the rhombomere 4-5 boundary

  6. Vhnf1 expression within the posterior neural tube (up to r5) promotes posterior and dorsal fates in the otic vesicle, at the expense of anterior and ventral fates.

  7. investigated the signaling pathways that regulate vhnf1 expression during pancreas development

  8. Data show that zebrafish mutants for Tcf2 fail to specify a single lumen in their gut (show GUSB Antibodies) tube and instead develop multiple lumens, and show that Tcf2 controls single lumen formation by regulating claudin15 and Na+/K+-ATPase (show ATP1A1 Antibodies) expression.

  9. vHNF1 plays crucial role at the earliest steps of liver induction: the acquisition of endoderm competence and the hepatic specification.

  10. It was concluded that hnf1b(hi2169) is hypomorphic to hnf1b(hi1843) and that, while hnf1b is required for r5/r6 gene expression in the hindbrain, r5/r6 gene expression can be experimentally induced independently of hnf1b anterior to the hindbrain.

HNF1 Homeobox B (HNF1B) Antigen Profile

Antigen Summary

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HNF1 Homeobox B (HNF1B)

  • HNF1 homeobox B (HNF1B) antibody
  • hepatocyte nuclear factor 1-beta-like (LOC100355480) antibody
  • HNF1 homeobox B (hnf1b) antibody
  • HNF1 homeobox B (Hnf1b) antibody
  • HNF1 homeobox Ba (hnf1ba) antibody
  • transcription factor 2 (hnf1b) antibody
  • AI385728 antibody
  • AI987804 antibody
  • chunp6877 antibody
  • FJHN antibody
  • HNF-1b antibody
  • HNF-1Beta antibody
  • hnf1-beta antibody
  • hnf1b antibody
  • Hnf1beta antibody
  • HNF2 antibody
  • HPC11 antibody
  • LF-B3 antibody
  • lfb3 antibody
  • MODY5 antibody
  • mst antibody
  • Tcf-2 antibody
  • Tcf2 antibody
  • vHNF-1 antibody
  • vHNF1 antibody

Protein level used designations for anti-HNF1 Homeobox B (HNF1B) Antibodies

transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor , HNF1 homeobox B , HNF-1-beta , HNF1 beta A , hepatocyte nuclear factor 1-beta , homeoprotein LFB3 , transcription factor 2, hepatic , FPC-binding protein , FPCB , HNF-1B , TCF-2 , variant hepatic nuclear factor 1 , hepatocyte nuclear factor-1 beta , transcription factor 2 , Transcription factor 2 hepatic , Transcription factor 2 hepatic; LF-B3; variant hepatic nuclear factor , Transcription factor 2, hepatic , Transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor , hepatocyte nuclear factor 1 beta , HNF-1-beta-A , HNF-1B-2 , HNF-1B-A , HNF1 homeobox b , hepatocyte nuclear factor 1-beta-2 , hepatocyte nuclear factor 1-beta-A , hob , xlFB3

GENE ID SPECIES
468227 Pan troglodytes
100057769 Equus caballus
100355480 Oryctolagus cuniculus
6928 Homo sapiens
398842 Xenopus laevis
427838 Gallus gallus
610402 Canis lupus familiaris
397002 Sus scrofa
21410 Mus musculus
25640 Rattus norvegicus
100734532 Cavia porcellus
503581 Bos taurus
792391 Danio rerio
380377 Xenopus laevis
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