HNF1B antibody (C-Term)

Catalog No. ABIN2778226

The Rabbit Polyclonal anti-HNF1B antibody (ABIN2778226) specifically detects HNF1B in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit and Sheep samples.

Quick Overview for HNF1B antibody (C-Term) (ABIN2778226)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNF1B Antibody

Binding Specificity: C-Term

Purpose: HNF1B Antibody - C-terminal region

Sequence: QGNNEITSSS TISHHGNSAM VTSQSVLQQV SPASLDPGHN LLSPDGKMIS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNF1B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34011-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1B

Background:

Background Information: HNF1B is a member of the transcription factor superfamily. It forms heterodimers with another member of this transcription factor family, HNF1A. Multiple alternatively spliced transcript variants have been described, however the biological validity all of these variants needs to be determined.

Gene Name: HNF1 homeobox B

Alternative Symbols: T2D, FJHN, HNF2, LFB3, RCAD, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, ADTKD3, HNF-1B, HNF1beta, HNF-1-beta

Protein Name: Hepatocyte nuclear factor 1-beta

Molecular Weight: 61kDa

Gene ID: 6928

NCBI Accession: NP_000449

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation