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Browse our IFNG Proteins (IFNG)

Full name:
Interferon gamma Proteins (IFNG)
On are 239 Interferon gamma (IFNG) Proteins from 23 different suppliers available. Additionally we are shipping IFNG Antibodies (1275) and IFNG Kits (435) and many more products for this protein. A total of 1984 IFNG products are currently listed.
list all proteins Gene Name GeneID UniProt
Rat IFNG IFNG 25712 P01581
Mouse IFNG IFNG 15978 P01580
IFNG 3458 P01579

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IFNG Proteins (IFNG) by Origin

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Top referenced IFNG Proteins

  1. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2018007 : Ealick, Cook, Vijay-Kumar, Carson, Nagabhushan, Trotta, Bugg: Three-dimensional structure of recombinant human interferon-gamma. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 5 references for ABIN2018007

  2. Ferret IFNG Protein expressed in Human Cells - ABIN2008793 : Greenlund, Farrar, Viviano, Schreiber: Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). in The EMBO journal 1994 (PubMed)
    Show all 4 references for ABIN2008793

  3. Mouse (Murine) IFNG Protein expressed in Human Cells - ABIN2008201 : Rinderknecht, OConnor, Rodriguez: Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation. in The Journal of biological chemistry 1984 (PubMed)
    Show all 4 references for ABIN2008201

  4. Rat (Rattus) IFNG Protein expressed in Human Cells - ABIN2009352 : Bach, Aguet, Schreiber: The IFN gamma receptor: a paradigm for cytokine receptor signaling. in Annual review of immunology 1997 (PubMed)
    Show all 4 references for ABIN2009352

  5. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1047219 : Gray, Leung, Pennica, Yelverton, Najarian, Simonsen, Derynck, Sherwood, Wallace, Berger, Levinson, Goeddel: Expression of human immune interferon cDNA in E. coli and monkey cells. in Nature 1982 (PubMed)
    Show all 3 references for ABIN1047219

  6. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305087 : Farrar, Schreiber: The molecular cell biology of interferon-gamma and its receptor. in Annual review of immunology 1993 (PubMed)
    Show all 3 references for ABIN1305087

  7. Rat (Rattus) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2666970 : De Maeyer, De Maeyer-Guignard: Interferon-gamma. in Current opinion in immunology 1992 (PubMed)
    Show all 2 references for ABIN2666970

  8. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305090 : Gray, Goeddel: Cloning and expression of murine immune interferon cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1983 (PubMed)
    Show all 2 references for ABIN1305090

  9. Human IFNG Protein expressed in HEK-293 Cells - ABIN2181249 : Derynck, Leung, Gray, Goeddel: Human interferon gamma is encoded by a single class of mRNA. in Nucleic acids research 1982 (PubMed)
    Show all 2 references for ABIN2181249

  10. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN934917 : POGO, BRAWERMAN, CHARGAFF: New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis. in Biochemistry 1970 (PubMed)

More Proteins for IFNG Interaction Partners

Mouse (Murine) Interferon gamma (IFNG) interaction partners

  1. the translatability of the IFNgamma-biomarker correlates from mouse to human, advocating the use of serum CXCL9 (show CXCL9 Proteins) or CXCL10 (show CXCL10 Proteins) as a means to monitor total IFNgamma activity in patients with secondary hemophagocytic lymphohistiocytosis.

  2. this study shows that IFN-gamma may be used to stimulate the immunomodulatory property of Wharton's jelly mesenchymal stem cells

  3. In biliary atresia, miR (show MLXIP Proteins)-155 regulates the IFN-gamma signaling pathway by targeting SOCS1 (show SOCS1 Proteins) expression.

  4. The reduction in fibrosis observed when IL-13 (show IL13 Proteins) signalling is suppressed is not dependent on increased IFN-gamma activity. Instead, by reducing compensatory increases in type 1-associated inflammation, therapeutic strategies that block IFN-gamma and IL-13 (show IL13 Proteins) activity simultaneously can confer greater protection from progressive fibrosis than IL-13 (show IL13 Proteins) blockade alone.

  5. Results indicate that rather than marking the most proinflammatory lymphocytes in diabetes development, IFN-gamma production could represent an attempted limitation of pathogenic CD8 (show CD8A Proteins)(+) T-cell activation.

  6. a novel negative feedback loop mediated by STAT3 (show STAT3 Proteins)-SOCS3 (show SOCS3 Proteins), which is tightly controlled by SENP1 (show SENP1 Proteins) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Proteins)), in IFN-gamma signaling, is reported.

  7. The presence of nterferon-gamma in the lung protected from infection, but when delivered to the periphery, interferon-gamma enhanced disease, potentially by dampening inflammatory cytokines.

  8. These results indicate that induction of unfolded protein response by IFN-gamma is an important cause of goblet cell-associated mucin (show SLC13A2 Proteins) deficiency observed in aqueous-deficient dry eye

  9. IFN-gamma signalling increases levels of central nervous system pro-inflammatory cytokines.

  10. this study shows that diosgenin-mediated anti-allergic effects are associated with increased number of Foxp3 (show FOXP3 Proteins)+ Treg cells expressing IFN-g

Guinea Pig Interferon gamma (IFNG) interaction partners

  1. Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 (show IL4 Proteins) ratio were significantly lower than those exposed to its low concentration.

Human Interferon gamma (IFNG) interaction partners

  1. +874T allele, which has been suggested to be associated with high IFN-gamma levels, was significantly higher in the controls and TT genotype was also more frequent in the control group. Thus, +874 T allele may be associated with resistance to tuberculosis in this Azeri population of Iran.

  2. Studied the relationship between polymorphisms in MBL (show MBL2 Proteins), TLR1 (show TLR1 Proteins), TLR2 and TLR6 (show TLR6 Proteins) encoding genes and stimulated IFN-gamma and IL-12 (show IL12A Proteins) ex vivo production in BCG (show SLC11A1 Proteins) osteitis survivors. Found that variant genotypes of the MBL2 (show MBL2 Proteins) gene (if homozygous) and variant genotypes of the TLR2 gene (only heterozygotes present) are associated with low IFN-gamma production.

  3. In biliary atresia, miR (show MLXIP Proteins)-155 regulates the IFN-gamma signaling pathway by targeting SOCS1 (show SOCS1 Proteins) expression.

  4. Interleukin 10 (show IL10 Proteins) and interleukin 10 receptor (show IL10RB Proteins) expression was also enriched in interferon gamma-expressing activated CD8 (show CD8A Proteins)(+) T cells. Treatment of anti-CD3 (show CD3 Proteins)/CD28 (show CD28 Proteins)-stimulated, purified CD8 (show CD8A Proteins)(+) T cells with interleukin 10 (show IL10 Proteins) alone could significantly enhance CD8 (show CD8A Proteins)(+) T cell survival, an effect dependent on interleukin 10 receptor (show IL10RB Proteins) expression

  5. STAT1 (show STAT1 Proteins) binding sites were identified on the putative miR-7 (show LILRB1 Proteins) promoter and stimulation of fibroblasts with the inflammatory cytokine, interferon-gamma (IFN-gamma), significantly increased miR-7 (show LILRB1 Proteins) transcriptional activity and resulted in upregulated miR-7 (show LILRB1 Proteins) and loss of EGFR (show EGFR Proteins).

  6. Tumor-associated M2 macrophages in mycosis fungoides acquire immunomodulatory function on exposure to IFN-alpha2a and IFN-gamma.

  7. These results indicate that induction of unfolded protein response by IFN-gamma is an important cause of goblet cell-associated mucin (show SLC13A2 Proteins) deficiency observed in aqueous-deficient dry eye

  8. RNAs isolated from HCV-replicating cells triggered robust IFN-beta (show IFNB1 Proteins) and IFN-lambda production through MDA5 (show IFIH1 Proteins).

  9. alkalization and the concomitant IFN-G upregulation in NK cells were sufficient to significantly delay tumor growth without any other immunotherapy. This effect was strictly dependent on NK cells

  10. Study found that miRNA-21 upregulation in plasma mediated the downregulation of IFN-gamma and resulted in the prevalence of stroke-associated infection, suggesting that miRNA-21 and IFN-gamma might be new biological predictors for stroke-associated infection and therapeutic targets

Pig (Porcine) Interferon gamma (IFNG) interaction partners

  1. The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR (show NR1I2 Proteins).

  2. Translational control of IL-18 (show IL18 Proteins) expression by its 5'-UTR limits production of IL-18 (show IL18 Proteins), resulting in restricted expression of mRNA and protein IFN-gamma in this model of crescentic glomerulonephritis(GN). Might amplify CD8 (show CD8A Proteins)+-mediated macrophage-dependent GN.

  3. selective changes in immature crypt cells induced by IFN-gamma bound to extracellular matrix could contribute to inappropriate responsiveness to commensal bacteria in inflammatory bowel diseases

  4. A functional single nucleotide polymorphism is reported in the coding region of IFN-gamma cDNA that markedly reduces antiviral activity of the IFN-gamma protein.

  5. The expression of IFN-gamma in recombiannt Lactococcus lactis as a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy is reported.

Cow (Bovine) Interferon gamma (IFNG) interaction partners

  1. The expression of multiple toll (show TLR4 Proteins)-like receptors, interferon-gamma, and interleukin-12 (IL-12 (show IL12A Proteins)) in cattle with low and high proviral loads of bovine leukemia virus are reported.

  2. Diet-driven interferon-gamma enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy.

  3. Data suggest that luteolytic factors (such as IFNG, tumor necrosis factor alpha (show TNF Proteins), and PGF2a) control expression of MMP1 (show MMP1 Proteins), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels.

  5. These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma occurring after parturition and an increase in IL-4 (show IL4 Proteins) production before calving.

  6. Genetic characterization of IFNG gene was done in resistant and susceptible animals of Sahiwal cattle (n = 95) and Friesian (n = 92).

  7. Data suggest that activation of gammadelta T cells to IFN-gamma production, NK cell-like killing plays a pivotal role in controlling virus infection.

  8. The differential expression levels of IFN-gamma mRNA between cattle and buffalo could be due to a conserved 4 base (GTCT) deletion in the promoter region of buffalo.

  9. SNPs in IFNG, IFNGR1 (show IFNGR1 Proteins) and R2, IL22 (show IL22 Proteins), and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

  10. Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus

Horse (Equine) Interferon gamma (IFNG) interaction partners

  1. These results indicate that in equine corpus luteum, cytokines TNF (show TNF Proteins), IFNG and FASL (show FASL Proteins) regulate nitric oxide activity, via eNOS (show NOS3 Proteins) expression modulation.

  2. IFN-gamma expression in foals appears to be controlled by DNA methylation (show HELLS Proteins) in the promoter region of Ifng. The age-associated demethylation of the DNA in foals may be induced by exposure to environmental antigens and their effect on lymphoproliferation (show FAS Proteins).

  3. These data show the presence of cytokines TNF (show TNF Proteins) and IFNG, and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  4. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Proteins) biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Proteins) production by T cells is mature.

Rhesus Monkey Interferon gamma (IFNG) interaction partners

  1. IFNgamma expression in colonic epithelial cells was regulated by TGFB1 (show TGFB1 Proteins).

  2. Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

  3. Data show that viral set-point in simian immunodeficiency virus diseasewas is associated with expression of interferon gamma -stimulated genes.

  4. Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine interferon-gamma.

Chimpanzee Interferon gamma (IFNG) interaction partners

  1. CD3 (show CD3 Proteins)(-) CD8 (show CD8A Proteins)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 (show IL15 Proteins) elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15 (show IL15 Proteins), CD8 (show CD8A Proteins) antigen, IFN-gamma]

IFNG Protein Profile

Protein Summary

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

Alternative names and synonyms associated with IFNG

  • interferon gamma (Ifng)
  • interferon gamma (IFNG)
  • interferon gamma-like (LOC101337436)
  • interferon, gamma (IFNG)
  • interferon, gamma (Ifng)
  • IFG protein
  • IFI protein
  • IFN-G protein
  • IFN-gamma protein
  • IFNG protein
  • IFNG2 protein

Protein level used designations for Interferon gamma Proteins (IFNG)

IFN-gamma , gamma interferon , interferon-gamma , interferon, gamma , interferon gamma , immune interferon , interferon-gama , boIFNG , interferon gamma type 2 , Interferon gamma , gamma-interferon , IFN gamma

25712 Rattus norvegicus
15978 Mus musculus
403801 Canis lupus familiaris
100379568 Cavia porcellus
101337436 Tursiops truncatus
3458 Homo sapiens
396991 Sus scrofa
396054 Gallus gallus
493965 Felis catus
281237 Bos taurus
100034181 Equus caballus
100860815 Capra hircus
443396 Ovis aries
101790439 Anas platyrhynchos
100008602 Oryctolagus cuniculus
574282 Macaca mulatta
100388952 Callithrix jacchus
101422877 Dasypus novemcinctus
100462659 Ailuropoda melanoleuca
101825431 Mesocricetus auratus
449517 Pan troglodytes
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