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Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305087
Farrar, Schreiber: The molecular cell biology of interferon-gamma and its receptor. in Annual review of immunology 1993
Show all 3 Pubmed References
Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN803857
Shiraki, Ishibashi, Hiruma, Nishikawa, Ikeda: Candida albicans abrogates the expression of interferon-gamma-inducible protein-10 in human keratinocytes. in FEMS immunology and medical microbiology 2008
Show all 2 Pubmed References
Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305090
Gray, Goeddel: Cloning and expression of murine immune interferon cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1983
Show all 2 Pubmed References
Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN804259
Apte, Baz, Groves, Kelso, Kienzle: Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells. in Proceedings of the National Academy of Sciences of the United States of America 2008
Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN413386
Kajiwara, Schiff, Voloudakis, Gama Sosa, Elder, Bozdagi, Buxbaum: A critical role for human caspase-4 in endotoxin sensitivity. in Journal of immunology (Baltimore, Md. : 1950) 2014
Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN934917
POGO, BRAWERMAN, CHARGAFF: New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis. in Biochemistry 1970
we identify interferon-gamma (IFN-gamma) as the key inflammatory mediator controlling sortilin-1 (show SORT1 Proteins) levels
this study shows that IFN-gamma induction by neutrophil-derived IL-17A (show IL17A Proteins) homodimer augments pulmonary antibacterial defense
ATF3 (show ATF3 Proteins)-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10 (show CXCL10 Proteins)-CXCR3 (show CXCR3 Proteins) axis at multiple levels.
IFNG mediates experimental cerebral malaria by signaling within both the hematopoietic and nonhematopoietic compartments.
identified TIM-4 (show TIMD4 Proteins) as a novel marker for B effector 1 (Be1) cells that depend on IFN-gamma for their proinflammatory activity; TIM-4 (show TIMD4 Proteins)(+) B cells are enriched for IFN-gamma-producing proinflammatory Be1 cells that enhance immune responsiveness and can be specifically targeted with anti-TIM-4 (show TIMD4 Proteins).
results demonstrate that a population of Thy1.2(+) non-NK innate-like cells present in the liver expresses IFN-gamma and can confer protection against M. avium infection in immunocompromised mice
Using IFN-gamma-deficient Th17 cells, study demonstrates the disease-amplifying role of Th17-derived IFN-gamma in dry eye disease pathogenesis. These results clearly demonstrate that Th17 cells mediate ocular surface autoimmunity through both IL-17A (show IL17A Proteins) and IFN-gamma.
identified IFNg, Neurturin (Nrtn (show NRTN Proteins)), and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation (show NEUROD1 Proteins) of Neural Precursor Cells in vivo.
Egr2 (show EGR2 Proteins) and 3 were essential to suppress Th1 (show HAND1 Proteins) differentiation in Th2 and Th17 conditions in vitro and also to control IFN-gamma-producing CD4 (show CD4 Proteins) and CD8 (show CD8A Proteins) T cells in response to virus infection
studies identify the requirement of IFN-gamma stimulation as a mechanism for BC-CML and AML GVL resistance, whereas independence from IFN-gamma renders CP-CML more GVL sensitive, even with a lower-level alloimmune response.
Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 (show IL4 Proteins) ratio were significantly lower than those exposed to its low concentration.
The performance of IFNG release assays is robust despite variations in the incubation temperature between 37 degrees C and 39 degrees C for the diagnosis of latent tuberculosis infection.
Elevated levels of systemic IFNgamma and IL-6 (show IL6 Proteins) implied that the CEACAM5 (show CEACAM5 Proteins)-specific T cells had undergone immune activation in vivo but only in patients receiving high-intensity pre-conditioning.
Condensin II(CAP-D3 and CAP-H2) and GAIT subunits associate with L1 RNA in a co-dependent manner, independent of IFN-gamma. These findings suggest that cooperation between the Condensin II and GAIT complexes may facilitate a novel mechanism of L1 repression, thus contributing to the maintenance of genome stability in somatic cells
The results highlight the importance of the inflammatory mediators, IFN-gamma and TLR4 (show TLR4 Proteins), in the pathogenesis of aseptic loosening; increased pro-inflammatory status was associated with early time to revision, whereas IL-4 (show IL4 Proteins) correlated with longer implant survival
Study provides evidence that mutations in IFNG confer melanoma cells resistance to ipilimumab.
High IFNG expression is associated with susceptibility to HPV-16 positive cervical cancer.
Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell-dependent indirect antidonor alloresponses and autocrine regulation of interferon-gamma production by Th1 (show TH1L Proteins) cells.
Our results suggest that TNF-alpha (show TNF Proteins), IFN-gamma and TGF-beta (show TGFB1 Proteins) function cooperatively to regulate the expressions of IL-6 (show IL6 Proteins) and MMP-9 (show MMP9 Proteins), and may play important roles in pathological behaviour of AMs (show MAT1A Proteins), such as bone resorption.
IFN-gamma is a promising immunological marker in vitiligo (show MITF Proteins) pathogenesis
These data suggest that prior exposure to IFN-gamma may leave an epigenetic mark on the chromatin that enhances airway cells' ability to resist infection, possibly via epigenetic upregulation of RIG-I (show DDX58 Proteins).
The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR (show NR1I2 Proteins).
Translational control of IL-18 (show IL18 Proteins) expression by its 5'-UTR limits production of IL-18 (show IL18 Proteins), resulting in restricted expression of mRNA and protein IFN-gamma in this model of crescentic glomerulonephritis(GN). Might amplify CD8 (show CD8A Proteins)+-mediated macrophage-dependent GN.
selective changes in immature crypt cells induced by IFN-gamma bound to extracellular matrix could contribute to inappropriate responsiveness to commensal bacteria in inflammatory bowel diseases
A functional single nucleotide polymorphism is reported in the coding region of IFN-gamma cDNA that markedly reduces antiviral activity of the IFN-gamma protein.
The expression of IFN-gamma in recombiannt Lactococcus lactis as a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy is reported.
The expression of multiple toll (show TLR4 Proteins)-like receptors, interferon-gamma, and interleukin-12 (IL-12 (show IL12A Proteins)) in cattle with low and high proviral loads of bovine leukemia virus are reported.
Diet-driven interferon-gamma enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy.
Data suggest that luteolytic factors (such as IFNG, tumor necrosis factor alpha (show TNF Proteins), and PGF2a) control expression of MMP1 (show MMP1 Proteins), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels.
These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma occurring after parturition and an increase in IL-4 (show IL4 Proteins) production before calving.
Genetic characterization of IFNG gene was done in resistant and susceptible animals of Sahiwal cattle (n = 95) and Friesian (n = 92).
Data suggest that activation of gammadelta T cells to IFN-gamma production, NK cell-like killing plays a pivotal role in controlling virus infection.
The differential expression levels of IFN-gamma mRNA between cattle and buffalo could be due to a conserved 4 base (GTCT) deletion in the promoter region of buffalo.
SNPs in IFNG, IFNGR1 (show IFNGR1 Proteins) and R2, IL22 (show IL22 Proteins), and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus
These results indicate that in equine corpus luteum, cytokines TNF (show TNF Proteins), IFNG and FASL (show FASL Proteins) regulate nitric oxide activity, via eNOS (show NOS3 Proteins) expression modulation.
IFN-gamma expression in foals appears to be controlled by DNA methylation (show HELLS Proteins) in the promoter region of Ifng. The age-associated demethylation of the DNA in foals may be induced by exposure to environmental antigens and their effect on lymphoproliferation (show FAS Proteins).
These data show the presence of cytokines TNF (show TNF Proteins) and IFNG, and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.
The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Proteins) biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Proteins) production by T cells is mature.
IFNgamma expression in colonic epithelial cells was regulated by TGFB1 (show TGFB1 Proteins).
Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.
Data show that viral set-point in simian immunodeficiency virus diseasewas is associated with expression of interferon gamma -stimulated genes.
Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine interferon-gamma.
CD3 (show CD3 Proteins)(-) CD8 (show CD8A Proteins)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 (show IL15 Proteins) elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15 (show IL15 Proteins), CD8 (show CD8A Proteins) antigen, IFN-gamma]
This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.
, gamma interferon
, interferon, gamma
, interferon gamma
, immune interferon
, interferon gamma type 2
, Interferon gamma
, IFN gamma