Browse our IFNG Proteins (IFNG)

Full name:
Interferon gamma Proteins (IFNG)
On are 255 Interferon gamma (IFNG) Proteins from 25 different suppliers available. Additionally we are shipping IFNG Antibodies (1367) and IFNG Kits (441) and many more products for this protein. A total of 2098 IFNG products are currently listed.
list all proteins Gene Name GeneID UniProt
Rat IFNG IFNG 25712 P01581
Mouse IFNG IFNG 15978 P01580
IFNG 3458 P01579

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IFNG Proteins (IFNG) by Origin

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Top referenced IFNG Proteins

  1. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2018007 : Ealick, Cook, Vijay-Kumar, Carson, Nagabhushan, Trotta, Bugg: Three-dimensional structure of recombinant human interferon-gamma. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 5 references for 2018007

  2. Ferret IFNG Protein expressed in Human Cells - ABIN2008793 : Greenlund, Farrar, Viviano, Schreiber: Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). in The EMBO journal 1994 (PubMed)
    Show all 4 references for 2008793

  3. Mouse (Murine) IFNG Protein expressed in Human Cells - ABIN2008201 : Rinderknecht, OConnor, Rodriguez: Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation. in The Journal of biological chemistry 1984 (PubMed)
    Show all 4 references for 2008201

  4. Rat (Rattus) IFNG Protein expressed in Human Cells - ABIN2009352 : Bach, Aguet, Schreiber: The IFN gamma receptor: a paradigm for cytokine receptor signaling. in Annual review of immunology 1997 (PubMed)
    Show all 4 references for 2009352

  5. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1047219 : Gray, Leung, Pennica, Yelverton, Najarian, Simonsen, Derynck, Sherwood, Wallace, Berger, Levinson, Goeddel: Expression of human immune interferon cDNA in E. coli and monkey cells. in Nature 1982 (PubMed)
    Show all 3 references for 1047219

  6. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305087 : Farrar, Schreiber: The molecular cell biology of interferon-gamma and its receptor. in Annual review of immunology 1993 (PubMed)
    Show all 3 references for 1305087

  7. Rat (Rattus) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2666970 : De Maeyer, De Maeyer-Guignard: Interferon-gamma. in Current opinion in immunology 1992 (PubMed)
    Show all 2 references for 2666970

  8. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305090 : Gray, Goeddel: Cloning and expression of murine immune interferon cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1983 (PubMed)
    Show all 2 references for 1305090

  9. Human IFNG Protein expressed in HEK-293 Cells - ABIN2181249 : Derynck, Leung, Gray, Goeddel: Human interferon gamma is encoded by a single class of mRNA. in Nucleic acids research 1982 (PubMed)
    Show all 2 references for 2181249

  10. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN934917 : POGO, BRAWERMAN, CHARGAFF: New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis. in Biochemistry 1970 (PubMed)

More Proteins for IFNG Interaction Partners

Mouse (Murine) Interferon gamma (IFNG) interaction partners

  1. identified IFNg, Neurturin (Nrtn (show NRTN Proteins)), and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation (show NEUROD1 Proteins) of Neural Precursor Cells in vivo.

  2. Egr2 (show EGR2 Proteins) and 3 were essential to suppress Th1 (show HAND1 Proteins) differentiation in Th2 and Th17 conditions in vitro and also to control IFN-gamma-producing CD4 (show CD4 Proteins) and CD8 (show CD8A Proteins) T cells in response to virus infection

  3. studies identify the requirement of IFN-gamma stimulation as a mechanism for BC-CML and AML GVL resistance, whereas independence from IFN-gamma renders CP-CML more GVL sensitive, even with a lower-level alloimmune response.

  4. Results demonstrate that the influence of IFN-gamma on acute lymphoblastic leukemia progression may not be mediated by selection of nascent transformed cells but rather through a general suppressor of cytokine signaling (show CISH Proteins) -mediated reduction in B-cell precursor proliferation.

  5. The results indicate that interferon-gamma is critical for the initial priming and differentiation of cytotoxic T lymphocytes residing in the periphery to produce the most effect antitumor function within the eye.

  6. The authors showed the synergistic negative regulation of the pro-inflammatory cytokine interferon-gamma (IFNgamma) and beta3 integrin (show ITGB3 Proteins) signaling in murine hematopoietic stem cells function by a novel definitive phenotyping of hematopoietic stem cells.

  7. We revealed that in mouse mesenchymal stem cells IFN-gamma-induced immunoregulation is media (show STAT3 Proteins)ted by early phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR inhibition, thereby promoting pSTAT1 nuclear translocation.

  8. data suggest that mPEG PV1 (show PLVAP Proteins)-Fab (show FANCB Proteins)' acts mainly on IFN-gamma-producing CD4 (show CD4 Proteins)+ T cells and emphasize that this specific CD28 (show CD28 Proteins) blockade strategy is a potential specific and alternative tool for the treatment of autoimmune disorders in the eye.

  9. this study showsthat the nature of the protective memory response depends closely on the route of infection and highlights the role of IFN-gamma-and IL-17RA (show IL17RA Proteins)-mediated responses in the control of mucosal infection by Brucella

  10. Study showed that the intraperitoneal administration of the exogenous cytokines IFN-gamma (to promote M1 microglia ) and IL-4 (show IL4 Proteins) (to promote M2 microglia) can correctly modulate the timing of the M1 to M2 ratio to affect epileptogenesis and to improve cognitive function in pilocarpine-induced status epilepticus.

Guinea Pig Interferon gamma (IFNG) interaction partners

  1. Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 (show IL4 Proteins) ratio were significantly lower than those exposed to its low concentration.

Human Interferon gamma (IFNG) interaction partners

  1. this study shows that genes associated with MAF (show MAF Proteins)-binding enhancers are suppressed in macrophages isolated from rheumatoid-arthritis patients, revealing a disease-associated signature of IFN-gamma-mediated repression

  2. This study presents preliminary evidence for the association between IFN +874 T/A, T/T, IL-10 (show IL10 Proteins) -1082 A/G genotypes, and hemophagocytic lymphohistiocytosis susceptibility in Chinese children

  3. Data suggest IFNG plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG dimerizes and binds to IFNGR1 (show IFNGR1 Proteins) in IFNGR1 (show IFNGR1 Proteins)/IFNGR2 (show IFNGR2 Proteins) hetero-multimer; STAT (show STAT1 Proteins) transcription factors are involved in non-canonical pathway. (IFNG = interferon gamma; IFNGR (show IFNGR1 Proteins) = IFNG receptor; STAT (show STAT1 Proteins) = signal transducers and activators of transcription)

  4. High levels of IFNG is associated with lyme disease.

  5. observed inverse relationship between the circulating levels of IFN-gamma and IL-17 (show IL17A Proteins) together with the reduction in the levels of memory-like CD4 (show CD4 Proteins)+ T cells expressing IL-17 (show IL17A Proteins) in children with SMA (show SMN1 Proteins) may suggest possible relocation of these cells in the deeper tissues for their pathological effect

  6. Preliminary results demonstrate concordance between IFNG +874 A/A genotype and low expression of IFNG in the Warao indigenous population

  7. A sustained exposure to IFN-gamma in human mesenchymal stem cells led to inhibition of STAT3 (show STAT3 Proteins) activity.

  8. Using a human oligodendroglioma (HOG (show MAPK14 Proteins)) cell line as a model, here we show that exosomes derived from TNF-a (show TNF Proteins)-treated "donor" cells, while being mildly toxic to fresh cultures (similar to individual cytokines), induce enhanced cell death when added to IFN-g-primed target cultures in a fashion resembling the effect of cytokine combination

  9. Fungus of the Sporothrix schenckii complex can produce skin lesions, commonly lymphocutaneous (LC) and fixed (F) forms of sporotrichosis. LC lesions present higher IL-10 (show IL10 Proteins) expression which could be related to regulatory mechanisms for compensating the tissue injury, however favoring fungal persistence in the lesions. Surprisingly, there were no differences in systemic and in situ IFN- gamma expression between CL and F pa...

  10. IL17A (show IL17A Proteins), IFNG, and FOXP3 (show FOXP3 Proteins) are increased in plaque-type psoriasis

Pig (Porcine) Interferon gamma (IFNG) interaction partners

  1. The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR (show NR1I2 Proteins).

  2. Translational control of IL-18 (show IL18 Proteins) expression by its 5'-UTR limits production of IL-18 (show IL18 Proteins), resulting in restricted expression of mRNA and protein IFN-gamma in this model of crescentic glomerulonephritis(GN). Might amplify CD8 (show CD8A Proteins)+-mediated macrophage-dependent GN.

  3. selective changes in immature crypt cells induced by IFN-gamma bound to extracellular matrix could contribute to inappropriate responsiveness to commensal bacteria in inflammatory bowel diseases

  4. A functional single nucleotide polymorphism is reported in the coding region of IFN-gamma cDNA that markedly reduces antiviral activity of the IFN-gamma protein.

  5. The expression of IFN-gamma in recombiannt Lactococcus lactis as a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy is reported.

Cow (Bovine) Interferon gamma (IFNG) interaction partners

  1. The expression of multiple toll (show TLR4 Proteins)-like receptors, interferon-gamma, and interleukin-12 (IL-12 (show IL12A Proteins)) in cattle with low and high proviral loads of bovine leukemia virus are reported.

  2. Diet-driven interferon-gamma enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy.

  3. Data suggest that luteolytic factors (such as IFNG, tumor necrosis factor alpha (show TNF Proteins), and PGF2a) control expression of MMP1 (show MMP1 Proteins), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels.

  5. These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma occurring after parturition and an increase in IL-4 (show IL4 Proteins) production before calving.

  6. Genetic characterization of IFNG gene was done in resistant and susceptible animals of Sahiwal cattle (n = 95) and Friesian (n = 92).

  7. Data suggest that activation of gammadelta T cells to IFN-gamma production, NK cell-like killing plays a pivotal role in controlling virus infection.

  8. The differential expression levels of IFN-gamma mRNA between cattle and buffalo could be due to a conserved 4 base (GTCT) deletion in the promoter region of buffalo.

  9. SNPs in IFNG, IFNGR1 (show IFNGR1 Proteins) and R2, IL22 (show IL22 Proteins), and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

  10. Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus

Horse (Equine) Interferon gamma (IFNG) interaction partners

  1. These results indicate that in equine corpus luteum, cytokines TNF (show TNF Proteins), IFNG and FASL (show FASL Proteins) regulate nitric oxide activity, via eNOS (show NOS3 Proteins) expression modulation.

  2. IFN-gamma expression in foals appears to be controlled by DNA methylation (show HELLS Proteins) in the promoter region of Ifng. The age-associated demethylation of the DNA in foals may be induced by exposure to environmental antigens and their effect on lymphoproliferation (show FAS Proteins).

  3. These data show the presence of cytokines TNF (show TNF Proteins) and IFNG, and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  4. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Proteins) biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Proteins) production by T cells is mature.

Rhesus Monkey Interferon gamma (IFNG) interaction partners

  1. IFNgamma expression in colonic epithelial cells was regulated by TGFB1 (show TGFB1 Proteins).

  2. Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

  3. Data show that viral set-point in simian immunodeficiency virus diseasewas is associated with expression of interferon gamma -stimulated genes.

  4. Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine interferon-gamma.

Chimpanzee Interferon gamma (IFNG) interaction partners

  1. CD3 (show CD3 Proteins)(-) CD8 (show CD8A Proteins)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 (show IL15 Proteins) elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15 (show IL15 Proteins), CD8 (show CD8A Proteins) antigen, IFN-gamma]

IFNG Protein Profile

Protein Summary

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

Alternative names and synonyms associated with IFNG

  • interferon gamma (Ifng)
  • interferon gamma (IFNG)
  • interferon gamma-like (LOC101337436)
  • interferon, gamma (IFNG)
  • interferon, gamma (Ifng)
  • IFG protein
  • IFI protein
  • IFN-G protein
  • IFN-gamma protein
  • IFNG protein
  • IFNG2 protein

Protein level used designations for Interferon gamma Proteins (IFNG)

IFN-gamma , gamma interferon , interferon-gamma , interferon, gamma , interferon gamma , immune interferon , interferon-gama , boIFNG , interferon gamma type 2 , Interferon gamma , gamma-interferon , IFN gamma

25712 Rattus norvegicus
15978 Mus musculus
403801 Canis lupus familiaris
100379568 Cavia porcellus
101337436 Tursiops truncatus
3458 Homo sapiens
396991 Sus scrofa
396054 Gallus gallus
493965 Felis catus
281237 Bos taurus
100034181 Equus caballus
100860815 Capra hircus
443396 Ovis aries
101790439 Anas platyrhynchos
100008602 Oryctolagus cuniculus
574282 Macaca mulatta
100388952 Callithrix jacchus
101422877 Dasypus novemcinctus
100462659 Ailuropoda melanoleuca
101825431 Mesocricetus auratus
449517 Pan troglodytes
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