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Browse our IFNG Proteins (IFNG)

Full name:
Interferon gamma Proteins (IFNG)
On www.antibodies-online.com are 241 Interferon gamma (IFNG) Proteins from 25 different suppliers available. Additionally we are shipping IFNG Antibodies (1305) and IFNG Kits (403) and many more products for this protein. A total of 1982 IFNG products are currently listed.
Synonyms:
IFG, IFI, IFN-G, IFN-gamma, IFNG, IFNG2
list all proteins Gene Name GeneID UniProt
Rat IFNG IFNG 25712 P01581
Mouse IFNG IFNG 15978 P01580
IFNG 3458 P01579

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IFNG Proteins (IFNG) by Origin

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Top referenced IFNG Proteins

  1. Ferret IFNG Protein expressed in Human Cells - ABIN2008793 : Greenlund, Farrar, Viviano, Schreiber: Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). in The EMBO journal 1994 (PubMed)
    Show all 4 references for ABIN2008793

  2. Mouse (Murine) IFNG Protein expressed in Human Cells - ABIN2008203 : Rinderknecht, OConnor, Rodriguez: Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation. in The Journal of biological chemistry 1984 (PubMed)
    Show all 4 references for ABIN2008203

  3. Rat (Rattus) IFNG Protein expressed in Human Cells - ABIN2009352 : Bach, Aguet, Schreiber: The IFN gamma receptor: a paradigm for cytokine receptor signaling. in Annual review of immunology 1997 (PubMed)
    Show all 4 references for ABIN2009352

  4. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305087 : Farrar, Schreiber: The molecular cell biology of interferon-gamma and its receptor. in Annual review of immunology 1993 (PubMed)
    Show all 3 references for ABIN1305087

  5. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1047219 : Gray, Leung, Pennica, Yelverton, Najarian, Simonsen, Derynck, Sherwood, Wallace, Berger, Levinson, Goeddel: Expression of human immune interferon cDNA in E. coli and monkey cells. in Nature 1982 (PubMed)
    Show all 3 references for ABIN1047219

  6. Rat (Rattus) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2666970 : De Maeyer, De Maeyer-Guignard: Interferon-gamma. in Current opinion in immunology 1992 (PubMed)
    Show all 2 references for ABIN2666970

  7. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305090 : Gray, Goeddel: Cloning and expression of murine immune interferon cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1983 (PubMed)
    Show all 2 references for ABIN1305090

  8. Human IFNG Protein expressed in HEK-293 Cells - ABIN2181249 : Derynck, Leung, Gray, Goeddel: Human interferon gamma is encoded by a single class of mRNA. in Nucleic acids research 1982 (PubMed)
    Show all 2 references for ABIN2181249

  9. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN934917 : POGO, BRAWERMAN, CHARGAFF: New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis. in Biochemistry 1970 (PubMed)

  10. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN413386 : Kajiwara, Schiff, Voloudakis, Gama Sosa, Elder, Bozdagi, Buxbaum: A critical role for human caspase-4 in endotoxin sensitivity. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Proteins for IFNG Interaction Partners

Mouse (Murine) Interferon gamma (IFNG) interaction partners

  1. these results suggest that IL-17 (show IL17A Proteins) intensified IFN-gamma-induced (show SAMHD1 Proteins) NOS2 (show NOS2 Proteins) upregulation and NO production by increasing the transcription activity of p-STAT1 (show STAT1 Proteins)(Y701) and NF-kappaB (show NFKB1 Proteins) in RAW 264.7 cells.

  2. Baicalin exhibited anti-influenza virus A (H1N1) activity in vitro and in vivo as a potent inducer of IFN-g in major IFN-g producing cells.

  3. Results indicated that Eomes (show EOMES Proteins) bound to the Ifng promoter and multiple conserved noncoding sequences in stimulation-dependent and stimulation-independent manners.

  4. IFN-gamma-treated mesenchymal stem cells strongly inhibit IL-10 (show IL10 Proteins) production by activated B cells by a mechanism requiring cell contact and involving the Cox-2 pathway.

  5. STAT4 (show STAT4 Proteins) has a pro-atherogenic role that is at least partially independent of Th1 (show HAND1 Proteins) cell-derived interferon-gamma

  6. STAT1 (show STAT1 Proteins) deficiency reprograms IFN signaling from priming toward suppression of TLR response via feedback regulation of STAT3 (show STAT3 Proteins).

  7. study implicates adaptive immune dysfunction, in particular IFN-gamma, in disorders characterized by social dysfunction and suggests a co-evolutionary link between social behaviour and an anti-pathogen immune response driven by IFN-gamma signalling

  8. Results indicate that production of interferon-gamma (IFN-gamma) is a predominant protective mechanism conferred by CD8 (show CD8A Proteins)(+) T cells in the course of neosporosis.

  9. TRIF (show RNF138 Proteins) mediates antibacterial defense during Gram-negative pneumonia, at least in part, by inducing IFN-x03B3; at the primary site of infection.

  10. Disabling of the erbB (show EGFR Proteins) pathway followed by IFNg modifies phenotype and enhances genotoxic eradication of breast tumors.

Guinea Pig Interferon gamma (IFNG) interaction partners

  1. Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 (show IL4 Proteins) ratio were significantly lower than those exposed to its low concentration.

Human Interferon gamma (IFNG) interaction partners

  1. Baicalin exhibited anti-influenza virus A (H1N1) activity in vitro and in vivo as a potent inducer of IFN-g in major IFN-g producing cells.

  2. Ultraviolet light-emitting-diode irradiation inhibits TNF-alpha (show TNF Proteins) and IFN-gamma-induced (show SAMHD1 Proteins) expression of ICAM-1 (show ICAM1 Proteins) and STAT1 (show STAT1 Proteins) phosphorylation in human keratinocytes.

  3. Decidual cells and natural killer cells at the embryo implantation site produce interferon-gamma.

  4. Study found TLR3 (show TLR3 Proteins) and IFNgamma to play an important role in Hepatitis E pathogenesis. Patients expressing high levels of TLR 3 (show TLR3 Proteins) and robust IFNgamma response are able to recover from the disease; while those with lower expression progress to acute liver failure.

  5. IFNG-AS1 (show PTGDR Proteins) regulated the expression of IFNG at both transcriptional and translational level in human CD4 (show CD4 Proteins)(+) T cells.

  6. Maximum risk for Pulmonary tuberculosis is associated with a combination of the AA genotypes of the polymorphic site +874A/Tof the IFNG gene and TT polymorphism G509T of the TGFB gene (AA/TT).

  7. Report IFNG response to lateny-associated antigens in cohort of subjects recently exposed to Mycobacterium tuberculosis.

  8. CD133(+) Hepatocellular carcinoma cancer stem cell resisted IFN-g-induced autophagy, which might also be a mechanism through which cancer stem cell resist immune eradication.

  9. Overexpression of KLF4 (show KLF4 Proteins) inhibited virus-induced activation of ISRE and IFN-b promoter in cells, while knockdown of KLF4 (show KLF4 Proteins) potentiated viral infection-triggered induction of IFNB1 (show IFNB1 Proteins) and downstream genes and attenuated viral replication.

  10. The study revealed a positive miR (show MLXIP Proteins)-155- IFN-gamma feedback loop in oral lichen planus CD4 (show CD4 Proteins)+ T cell, which might contribute to the Th1 (show TH1L Proteins)-dominated immune response.

Pig (Porcine) Interferon gamma (IFNG) interaction partners

  1. The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR (show NR1I2 Proteins).

  2. Translational control of IL-18 (show IL18 Proteins) expression by its 5'-UTR limits production of IL-18 (show IL18 Proteins), resulting in restricted expression of mRNA and protein IFN-gamma in this model of crescentic glomerulonephritis(GN). Might amplify CD8 (show CD8A Proteins)+-mediated macrophage-dependent GN.

  3. selective changes in immature crypt cells induced by IFN-gamma bound to extracellular matrix could contribute to inappropriate responsiveness to commensal bacteria in inflammatory bowel diseases

  4. A functional single nucleotide polymorphism is reported in the coding region of IFN-gamma cDNA that markedly reduces antiviral activity of the IFN-gamma protein.

  5. The expression of IFN-gamma in recombiannt Lactococcus lactis as a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy is reported.

Cow (Bovine) Interferon gamma (IFNG) interaction partners

  1. Data suggest that luteolytic factors (such as IFNG, tumor necrosis factor alpha (show TNF Proteins), and PGF2a) control expression of MMP1 (show MMP1 Proteins), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  2. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels.

  3. These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma occurring after parturition and an increase in IL-4 (show IL4 Proteins) production before calving.

  4. Genetic characterization of IFNG gene was done in resistant and susceptible animals of Sahiwal cattle (n = 95) and Friesian (n = 92).

  5. Data suggest that activation of gammadelta T cells to IFN-gamma production, NK cell-like killing plays a pivotal role in controlling virus infection.

  6. The differential expression levels of IFN-gamma mRNA between cattle and buffalo could be due to a conserved 4 base (GTCT) deletion in the promoter region of buffalo.

  7. SNPs in IFNG, IFNGR1 (show IFNGR1 Proteins) and R2, IL22 (show IL22 Proteins), and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

  8. Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus

  9. The upregulation of TNFRI (show TNFRSF1A Proteins) mRNA expression by IFNG suggests that TNF (show TNF Proteins) and IFNG synergistically affect the death of luteal endothelial cells resulting in acute luteolysis

  10. The entire bovine IFN-gamma gene (BoIFNG) and 2605 bp of its promoter DNA were sequenced. A comprehensive survey for polymorphisms in the bovine IFN-gamma gene reveals a highly polymorphic intronic DNA sequence allowing improved genotyping of Bovinae.

Horse (Equine) Interferon gamma (IFNG) interaction partners

  1. These results indicate that in equine corpus luteum, cytokines TNF (show TNF Proteins), IFNG and FASL (show FASL Proteins) regulate nitric oxide activity, via eNOS (show NOS3 Proteins) expression modulation.

  2. IFN-gamma expression in foals appears to be controlled by DNA methylation (show HELLS Proteins) in the promoter region of Ifng. The age-associated demethylation of the DNA in foals may be induced by exposure to environmental antigens and their effect on lymphoproliferation (show FAS Proteins).

  3. These data show the presence of cytokines TNF (show TNF Proteins) and IFNG, and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  4. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Proteins) biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Proteins) production by T cells is mature.

Rhesus Monkey Interferon gamma (IFNG) interaction partners

  1. IFNgamma expression in colonic epithelial cells was regulated by TGFB1 (show TGFB1 Proteins).

  2. Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

  3. Data show that viral set-point in simian immunodeficiency virus diseasewas is associated with expression of interferon gamma -stimulated genes.

  4. Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine interferon-gamma.

Chimpanzee Interferon gamma (IFNG) interaction partners

  1. CD3 (show CD3 Proteins)(-) CD8 (show CD8A Proteins)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 (show IL15 Proteins) elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15 (show IL15 Proteins), CD8 (show CD8A Proteins) antigen, IFN-gamma]

IFNG Protein Profile

Protein Summary

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

Alternative names and synonyms associated with IFNG

  • interferon gamma (Ifng)
  • interferon gamma (IFNG)
  • interferon gamma-like (LOC101337436)
  • interferon, gamma (IFNG)
  • interferon, gamma (Ifng)
  • IFG protein
  • IFI protein
  • IFN-G protein
  • IFN-gamma protein
  • IFNG protein
  • IFNG2 protein

Protein level used designations for Interferon gamma Proteins (IFNG)

IFN-gamma , gamma interferon , interferon-gamma , interferon, gamma , interferon gamma , immune interferon , interferon-gama , boIFNG , interferon gamma type 2 , Interferon gamma , gamma-interferon , IFN gamma

GENE ID SPECIES
25712 Rattus norvegicus
15978 Mus musculus
403801 Canis lupus familiaris
100379568 Cavia porcellus
101337436 Tursiops truncatus
3458 Homo sapiens
396991 Sus scrofa
396054 Gallus gallus
493965 Felis catus
281237 Bos taurus
100034181 Equus caballus
100860815 Capra hircus
443396 Ovis aries
101790439 Anas platyrhynchos
100008602 Oryctolagus cuniculus
574282 Macaca mulatta
100388952 Callithrix jacchus
101422877 Dasypus novemcinctus
100462659 Ailuropoda melanoleuca
101825431 Mesocricetus auratus
449517 Pan troglodytes
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