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Browse our Angiotensin II Type-1 Receptor Proteins (AGTR1)

Full name:
Angiotensin II Receptor, Type 1 Proteins (AGTR1)
On are 12 Angiotensin II Receptor, Type 1 (AGTR1) Proteins from 6 different suppliers available. Additionally we are shipping Angiotensin II Type-1 Receptor Antibodies (99) and Angiotensin II Type-1 Receptor Kits (41) and many more products for this protein. A total of 159 Angiotensin II Type-1 Receptor products are currently listed.
1810074K20Rik, AG2S, Agtr-1a, Agtr-1b, AGTR1, agtr1-A, agtr1.2, AGTR1A, AGTR1B, AGTR2, AI551199, Angtr-1a, Angtr-1b, at1, AT1-R, AT1a, AT1AR, AT1B, AT1BR, AT1R, at2, at2r, AT2R1, AT2R1A, AT2R1B, AT3, AT1R, atgr2, HAT1R, mrx88, XAT-1, zgc:113016
list all proteins Gene Name GeneID UniProt
AGTR1 185 P30556
AGTR1 11607 P29754
AGTR1 81638 P29089

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Angiotensin II Type-1 Receptor Proteins (AGTR1) by Origin

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More Proteins for Angiotensin II Type-1 Receptor Interaction Partners

Cow (Bovine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Data suggest that AGTR2 (show AGTR2 Proteins) (and angiotensin-converting enzyme (show ACE Proteins)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.

  2. These results identify bTREK-1 K(+) channels as a pivotal control point where ANG II (show AGT Proteins) receptor activation is transduced to depolarization-dependent Ca(2 (show CA2 Proteins)+) entry and aldosterone secretion.

  3. Angiotensin II (ANGII) inhibits adrenocortical cell KCNK2 in an ATP dependent, PLC/PKC independent manner.

  4. data suggest that G alpha(i3), Shc (show SHC1 Proteins), Grb2 (show GRB2 Proteins), Ras, and Raf-1 (show RAF1 Proteins) link Src (show SRC Proteins) to activation of MAPK (show MAPK1 Proteins) and to the AT(2)-dependent increase in eNOS (show NOS3 Proteins) expression in PAECs

  5. Abundance of AGTR2 (show AGTR2 Proteins) mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change

Pig (Porcine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. AT1 and AT2 (show AGTR2 Proteins) receptors heterodimerize and are involved in the angiotensin II effect on SERCA (show ATP2A3 Proteins) in proximal kidney tubules.

  2. A critical role for lipid raft microdomains in AGTR1-mediated signal transduction in neonatal glomerular mesengial cells.

  3. AT1 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.

  4. Glomerular eNOS (show NOS3 Proteins) gene expression was studied during postnatal maturation and AT1 receptor (show AGTRAP Proteins) inhibition.

Rabbit Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Ang II (show AGT Proteins) increase HTFs proliferation, migration, and phenotype transition, suggesting that Ang II (show AGT Proteins) may play a role in wound healing after trabeculectomy.

  2. Renal AT1R expression was increased by approximately 67% and AT2R (show AGTR2 Proteins) expression was decreased by approximately 87% in rabbits with heart failure; however, kidneys from denervated rabbits with heart failure showed a near normalization in the expression of these receptors.

  3. Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia (show RNF111 Proteins)-mediated downregulation of Smad7 (show SMAD7 Proteins).

  4. Following inflammation in the femoral artery angiotensin AT1 receptors are activated along with thromboxane receptors.

  5. Corneal cells express ACE (show ACE Proteins), AT(1) and AT(2)receptors. ACE (show ACE Proteins) inhibitor enalapril decreased corneal angiogenesis in VEGF (show VEGFA Proteins)-induced corneal neovascularization. ACE (show ACE Proteins) inhibitors may be novel therapy to treat corneal angiogenesis.

  6. investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line

Human Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. ACE (show ACE Proteins) I/D is associated with Abdominal Aortic Aneurysm , and 1166A>C AT1R with the size of the aneurysm, while -1562C>T MMP-9 (show MMP9 Proteins) and CCR5Delta32 polymorphisms are most probably not associated with Abdominal Aortic Aneurysm in Croatian patients.

  2. AT1R A1166C polymorphism impacts an ultrasonographically-defined human plaque phenotype, with intra-plaque AT1R and miR (show MLXIP Proteins)-155 expression altered in advanced carotid atherosclerosis

  3. Transgenic mice containing Hap (show SAFB Proteins)-I and Hap (show SAFB Proteins)-II of the human AT1R gene in a 166-kb bacterial artificial chromosome were generated. Mice containing Hap (show SAFB Proteins)-I suffered from significantly higher neurological deficits and larger brain infarcts than Hap (show SAFB Proteins) II. Increased expression of hAT1R rendered Hap (show SAFB Proteins)-I TG mice susceptible to stroke-related pathology.

  4. Epigallocatechin-3-gallate inhibits Ang II-induced CRP generation by interfering with AT1-ROS-ERK1/2 signal pathway in hepatocytes, preventing inflammation.

  5. observed significantly higher prevalence of ACE (show ACE Proteins) DD and AGTR1 1166CC genotypes in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) patients. Also, 235TT genotype of AGT (show AGXT Proteins) (M235T) was significantly associated with enhanced risk of the disease phenotype in HCM, DCM, and RCM (show Unc5c Proteins).

  6. CAV-1 (show CAV1 Proteins), FOXM1 (show FOXM1 Proteins) and AT1-R may be potential markers of tumorigenesis in certain types of cancer in vitro.

  7. no correlation was established between the occurrence of CHD (show CHDH Proteins) and AGTR1 haplotypes present at frequencies greater than 3%.

  8. peripheral and central arterial pressures and pulse wave augmentation indexes (AIx(P), AIx(C1), AIx(C2)), pulse wave velocity (PWV), daily urinary sodium excretion were measured and did genetic studies of AGTR1 A1166C and AGTR2 (show AGTR2 Proteins) G1675A polymorphisms.

  9. Monocytes of patients with systemic sclerosis presented an increased angiotensin II Type 1 receptor (AT1R)/AT2R (show AGTR2 Proteins) ratio compared with those of healthy donors.

  10. These data suggest that AT2R inhibits ligand-induced AT1R signaling through the PKC-dependent pathway.

Guinea Pig Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

Mouse (Murine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Genetic inhibition of Gpx1 (show GPX1 Proteins) potentiates cocaine-induced renal damage via activation of AT1R (show AGTRAP Proteins) by inhibition of PI3K-Akt (show AKT1 Proteins) signaling.

  2. AT1R (show AGTRAP Proteins) up-regulation in the stomach may help compensate for interstitial cells of Cajal loss in diabetic mice.

  3. These results suggest that in the absence of AT2R (show AGTR2 Proteins), wound healing rate is accelerated, but yielded worse skin quality.

  4. Results indicate that Ang III (show AGT Proteins) produces nociceptive behavior similar to Ang II (show AGT Proteins), and suggest that the phosphorylation of p38 MAPK (show MAPK14 Proteins) mediated through AT1 (show SLC33A1 Proteins) receptors on spinal astrocytes and neurons contributes to Ang II (show AGT Proteins)- and III-induced nociceptive behavior

  5. Angiotensin II stimulation alters vasomotor response to adenosine in mouse mesenteric artery: role for A1 and A2B (show ADORA2B Proteins) adenosine receptors

  6. CRF-AT1a R((-/-)) mice exhibit less freezing than wild-type mice during tests of conditioned fear.

  7. Results support functional interactions between AT1 (show SLC33A1 Proteins) receptors and TLR4 (show TLR4 Proteins) in mediating ANG II (show AGT Proteins)-dependent microglial activation and oxidative stress within the hypothalamic paraventricular nucleus.

  8. These results indicate that Ang-II (show AGT Proteins) induces cardiac fibroblast proliferation and migration in part via Nox4 (show NOX4 Proteins)/ROS (show ROS1 Proteins)-dependent IL-18 (show IL18 Proteins) induction and MMP9 (show MMP9 Proteins) activation, and may involve AT1 (show SLC33A1 Proteins)/Nox4 (show NOX4 Proteins) physical association.

  9. AT1 receptor (show AGTRAP Proteins) contributes to plantaris muscle development and hypertrophy via atrogin-1 (show FBXO32 Proteins)

  10. hGRK4gamma(142V) phosphorylates histone deacetylase (show HDAC1 Proteins) type 1 and promotes its nuclear export to the cytoplasm, resulting in increased AT1R (show AGTRAP Proteins) expression and greater pressor response to angiotensin II.

Angiotensin II Type-1 Receptor (AGTR1) Protein Profile

Protein Summary

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed\; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Alternative names and synonyms associated with Angiotensin II Type-1 Receptor (AGTR1)

  • angiotensin II receptor, type 1 (AGTR1)
  • angiotensin 2 receptor, type 1 (agtr1-b)
  • angiotensin II receptor, type 2 (AGTR2)
  • angiotensin II subtype 2 receptor (AT2)
  • angiotensin II receptor, type 2 (agtr2)
  • angiotensin 2 receptor, type 2 (agtr2)
  • angiotensin II receptor, type 1 (Agtr1)
  • angiotensin II receptor, type 1a (Agtr1a)
  • angiotensin II receptor, type 1b (Agtr1b)
  • type-1 angiotensin II receptor-like (LOC100519976)
  • 1810074K20Rik protein
  • AG2S protein
  • Agtr-1a protein
  • Agtr-1b protein
  • AGTR1 protein
  • agtr1-A protein
  • agtr1.2 protein
  • AGTR1A protein
  • AGTR1B protein
  • AGTR2 protein
  • AI551199 protein
  • Angtr-1a protein
  • Angtr-1b protein
  • at1 protein
  • AT1-R protein
  • AT1a protein
  • AT1AR protein
  • AT1B protein
  • AT1BR protein
  • AT1R protein
  • at2 protein
  • at2r protein
  • AT2R1 protein
  • AT2R1A protein
  • AT2R1B protein
  • AT3 protein
  • AT1R protein
  • atgr2 protein
  • HAT1R protein
  • mrx88 protein
  • XAT-1 protein
  • zgc:113016 protein

Protein level used designations for AGTR1

Type-1 angiotensin II receptor , angiotensin receptor , AT1-2 , angiotensin 2 receptor, type 1, gene 2 , angiotensin 2 receptor, type 1-B , angiotensin II receptor, type 1 , angiotensin II receptor, type 1-B , angiotensin II type-1 receptor 2 , angiotensin type 1 receptor , type-1 angiotensin II receptor B , type-1-like angiotensin II receptor 2 , type-1 angiotensin II receptor , angiotensin II receptor type 2 , angiotensin II type 2 receptor , angiotensin receptor 2 , angiotensin II receptor, type 2 , Type-2 angiotensin II receptor , angiotensin II subtype 2 receptor, AT2 , type-2 angiotensin II receptor , angiotensin type II receptor , type-2 angiotensin II receptor-like , type-1B angiotensin II receptor , angiotensin II type 1 receptor , AT1 , angiotensin II receptor 1 , angiotensin II type-1 receptor , angiotensin receptor 1 , AT1 ANG II receptor , AT1 angiotensin II receptor , angiotensin II type-1A receptor , angiotensin receptor 1a , type-1A angiotensin II receptor , Angiotensin II receptor, type 1 (AT1B) , angiotensin II receptor, type-1 , angiotensin II type-1B receptor , angiotensin receptor 1b , AT3 , Angiotensin II type-1 receptor

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100009329 Oryctolagus cuniculus
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100405479 Callithrix jacchus
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185 Homo sapiens
403836 Canis lupus familiaris
281607 Bos taurus
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396065 Gallus gallus
100192325 Cavia porcellus
100286872 Sus scrofa
443107 Ovis aries
460762 Pan troglodytes
11607 Mus musculus
81638 Rattus norvegicus
11608 Mus musculus
100519976 Sus scrofa
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