Browse our Angiotensin II Type-1 Receptor Proteins (AGTR1)

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Angiotensin II Receptor, Type 1 Proteins (AGTR1)
On are 10 Angiotensin II Receptor, Type 1 (AGTR1) Proteins from 4 different suppliers available. Additionally we are shipping Angiotensin II Type-1 Receptor Antibodies (101) and Angiotensin II Type-1 Receptor Kits (74) and many more products for this protein. A total of 193 Angiotensin II Type-1 Receptor products are currently listed.
1810074K20Rik, AG2S, Agtr-1a, Agtr-1b, AGTR1, agtr1-A, agtr1.2, AGTR1A, AGTR1B, AGTR2, AI551199, Angtr-1a, Angtr-1b, at1, AT1-R, AT1a, AT1AR, AT1B, AT1BR, AT1R, at2, at2r, AT2R1, AT2R1A, AT2R1B, AT3, AT1R, atgr2, HAT1R, mrx88, XAT-1, zgc:113016
list all proteins Gene Name GeneID UniProt
AGTR1 185 P30556
AGTR1 11607 P29754
AGTR1 81638 P29089

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Angiotensin II Type-1 Receptor Proteins (AGTR1) by Origin

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More Proteins for Angiotensin II Type-1 Receptor Interaction Partners

Cow (Bovine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Data suggest that AGTR2 (show AGTR2 Proteins) (and angiotensin-converting enzyme (show ACE Proteins)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.

  2. These results identify bTREK-1 K(+) channels as a pivotal control point where ANG II (show AGT Proteins) receptor activation is transduced to depolarization-dependent Ca(2 (show CA2 Proteins)+) entry and aldosterone secretion.

  3. Angiotensin II (ANGII) inhibits adrenocortical cell KCNK2 in an ATP dependent, PLC/PKC independent manner.

  4. data suggest that G alpha(i3), Shc (show SHC1 Proteins), Grb2 (show GRB2 Proteins), Ras, and Raf-1 (show RAF1 Proteins) link Src (show SRC Proteins) to activation of MAPK (show MAPK1 Proteins) and to the AT(2)-dependent increase in eNOS (show NOS3 Proteins) expression in PAECs

  5. Abundance of AGTR2 (show AGTR2 Proteins) mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change

Pig (Porcine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.

  2. AT1 and AT2 (show AGTR2 Proteins) receptors heterodimerize and are involved in the angiotensin II effect on SERCA (show ATP2A3 Proteins) in proximal kidney tubules.

  3. A critical role for lipid raft microdomains in AGTR1-mediated signal transduction in neonatal glomerular mesengial cells.

  4. AT1 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.

  5. Glomerular eNOS (show NOS3 Proteins) gene expression was studied during postnatal maturation and AT1 receptor (show AGTRAP Proteins) inhibition.

Rabbit Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Ang II (show AGT Proteins) increase HTFs proliferation, migration, and phenotype transition, suggesting that Ang II (show AGT Proteins) may play a role in wound healing after trabeculectomy.

  2. Renal AT1R expression was increased by approximately 67% and AT2R (show AGTR2 Proteins) expression was decreased by approximately 87% in rabbits with heart failure; however, kidneys from denervated rabbits with heart failure showed a near normalization in the expression of these receptors.

  3. Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia (show RNF111 Proteins)-mediated downregulation of Smad7 (show SMAD7 Proteins).

  4. Following inflammation in the femoral artery angiotensin AT1 receptors are activated along with thromboxane receptors.

  5. Corneal cells express ACE (show ACE Proteins), AT(1) and AT(2)receptors. ACE (show ACE Proteins) inhibitor enalapril decreased corneal angiogenesis in VEGF (show VEGFA Proteins)-induced corneal neovascularization. ACE (show ACE Proteins) inhibitors may be novel therapy to treat corneal angiogenesis.

  6. investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line

Human Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Angiotensin II type 1 receptors promote ADAM17 (show ADAM17 Proteins)-mediated ACE2 (show ACE2 Proteins) shedding in the brain of hypertensive patients.

  2. Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)

  3. our results show the pivotal mechanisms of AT1R-induced harmful phenotype of Plasmodium-specific CD8 (show CD8A Proteins)(+) T cells during blood-stage malaria.

  4. Ouabain stimulates NKA (show TAC1 Proteins) in renal proximal tubule cells through an angiotensin/AT1R-dependent mechanism and that this pathway contributes to cardiac glycoside associated hypertension.

  5. Mutations within transmembrane domains IV, V, VI, and VII (show TH Proteins) had no effect on angiotensin-mediated beta-arrestin1 (show ARRB1 Proteins) recruitment; however, they exhibited differential effects on the assembly of AT1R into oligomeric complexes.

  6. Our findings provide evidence that induction of APP (show APP Proteins) shedding via Ang II (show AGT Proteins)/AT1 receptor (show AGTRAP Proteins) stimulation is effected by G protein activation with Gbg (show CFB Proteins) subunits playing important roles.

  7. AT1R-Ab and anti-endothelial cell antibodies may identify patients at higher risk for antibody mediated injury, particularly in the presence of HLA-donor specific antibodies.

  8. Structure and Function of Cross-class Complexes of G Protein-coupled Secretin (show SECR Proteins) and Angiotensin 1a Receptors.

  9. studied the clinical significance of the AT1RA1166C receptor polymorphism and its relationship with serum concentration of lipids, oxidant/antioxidant systems and vascular adhesion protein-1(VAP-1 (show AOC3 Proteins)) in 100 psoriatic patients and 100 gender- and age-matched unrelated healthy controls from west population of Iran

  10. angiotensin II Type 1 receptor genotype may influence the clinical expression of vasculopathy in systemic sclerosis patients.

Guinea Pig Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

Mouse (Murine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

  1. Perivascular Adipose Tissue Angiotensin II Type 1a Receptor Promotes Vascular Inflammation and Aneurysm formation in apolipoprotein E (show APOE Proteins)-deficient (ApoE (show APOE Proteins)(-/-)) mice.

  2. The findings suggested that ox-LDL could induce cardiac hypertrophy through the direct association of AT1-R and LOX-1 (show OLR1 Proteins).

  3. Mice lacking the AT1A receptor specifically in LEPR-expressing cells failed to show an increase in resting metabolic rate in response to a high-fat diet and deoxycorticosterone acetate-salt (DOCA-salt) treatments, but blood pressure control remained intact.

  4. In wild-type, total (tNCC (show TNNC1 Proteins)) and phosphorylated (pNCC) NCC (show SLC12A3 Proteins) protein expressions were 1.8- and 4.6-fold higher in females compared with males, consistent with the larger response to HCTZ. In AT1a receptor knockout mice, tNCC (show TNNC1 Proteins) and pNCC increased significantly in males to levels not different from those in females.

  5. This study showed that activation of the AT1a receptor may contribute to maintenance of the glomerular structure against hypertensive renal damage.

  6. Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.

  7. Results provide evidence that blockade of the AT1a receptor could have some effects on browning of WAT, with inhibitory effects on adipose tissue-derived stem cells differentiation into adipocytes.

  8. Results suggest the involvement of angiotensin II (Ang II), through its angiotensin type-1 receptor (AT1R (show AGTRAP Proteins)) in the inflammation induced by Aah (show ASPH Proteins) venom, in the heart and the aorta.

  9. Structure and Function of Cross-class Complexes of G Protein-coupled Secretin (show SECR Proteins) and Angiotensin 1a Receptors.

  10. Genetic inhibition of Gpx1 (show GPX1 Proteins) potentiates cocaine-induced renal damage via activation of AT1R (show AGTRAP Proteins) by inhibition of PI3K-Akt (show AKT1 Proteins) signaling.

Angiotensin II Type-1 Receptor (AGTR1) Protein Profile

Protein Summary

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed\; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Alternative names and synonyms associated with Angiotensin II Type-1 Receptor (AGTR1)

  • angiotensin II receptor, type 1 (AGTR1)
  • angiotensin 2 receptor, type 1 (agtr1-b)
  • angiotensin II receptor, type 2 (AGTR2)
  • angiotensin II subtype 2 receptor (AT2)
  • angiotensin II receptor, type 2 (agtr2)
  • angiotensin 2 receptor, type 2 (agtr2)
  • angiotensin II receptor, type 1 (Agtr1)
  • angiotensin II receptor, type 1a (Agtr1a)
  • angiotensin II receptor, type 1b (Agtr1b)
  • type-1 angiotensin II receptor-like (LOC100519976)
  • 1810074K20Rik protein
  • AG2S protein
  • Agtr-1a protein
  • Agtr-1b protein
  • AGTR1 protein
  • agtr1-A protein
  • agtr1.2 protein
  • AGTR1A protein
  • AGTR1B protein
  • AGTR2 protein
  • AI551199 protein
  • Angtr-1a protein
  • Angtr-1b protein
  • at1 protein
  • AT1-R protein
  • AT1a protein
  • AT1AR protein
  • AT1B protein
  • AT1BR protein
  • AT1R protein
  • at2 protein
  • at2r protein
  • AT2R1 protein
  • AT2R1A protein
  • AT2R1B protein
  • AT3 protein
  • AT1R protein
  • atgr2 protein
  • HAT1R protein
  • mrx88 protein
  • XAT-1 protein
  • zgc:113016 protein

Protein level used designations for AGTR1

Type-1 angiotensin II receptor , angiotensin receptor , AT1-2 , angiotensin 2 receptor, type 1, gene 2 , angiotensin 2 receptor, type 1-B , angiotensin II receptor, type 1 , angiotensin II receptor, type 1-B , angiotensin II type-1 receptor 2 , angiotensin type 1 receptor , type-1 angiotensin II receptor B , type-1-like angiotensin II receptor 2 , type-1 angiotensin II receptor , angiotensin II receptor type 2 , angiotensin II type 2 receptor , angiotensin receptor 2 , angiotensin II receptor, type 2 , Type-2 angiotensin II receptor , angiotensin II subtype 2 receptor, AT2 , type-2 angiotensin II receptor , angiotensin type II receptor , type-2 angiotensin II receptor-like , type-1B angiotensin II receptor , angiotensin II type 1 receptor , AT1 , angiotensin II receptor 1 , angiotensin II type-1 receptor , angiotensin receptor 1 , AT1 ANG II receptor , AT1 angiotensin II receptor , angiotensin II type-1A receptor , angiotensin receptor 1a , type-1A angiotensin II receptor , Angiotensin II receptor, type 1 (AT1B) , angiotensin II receptor, type-1 , angiotensin II type-1B receptor , angiotensin receptor 1b , AT3 , Angiotensin II type-1 receptor

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733586 Sus scrofa
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100009329 Oryctolagus cuniculus
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100405479 Callithrix jacchus
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185 Homo sapiens
403836 Canis lupus familiaris
281607 Bos taurus
100009164 Oryctolagus cuniculus
396065 Gallus gallus
100192325 Cavia porcellus
100286872 Sus scrofa
443107 Ovis aries
460762 Pan troglodytes
11607 Mus musculus
81638 Rattus norvegicus
11608 Mus musculus
100519976 Sus scrofa
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