Browse our anti-CD25 (IL2RA) Antibodies

On www.antibodies-online.com are 1126 Interleukin 2 Receptor, alpha (IL2RA) Antibodies from 35 different suppliers available. Additionally we are shipping CD25 Kits (84) and CD25 Proteins (56) and many more products for this protein. A total of 1277 CD25 products are currently listed.
Synonyms:
CD25, HEM45, IDDM10, IL-2RA, Il2r, IL2RAC, Ly-43, TCGFR
list all antibodies Gene Name GeneID UniProt
IL2RA 3669 Q96AZ6
IL2RA 25704 P26897
IL2RA 16184 P01590

Most Popular Reactivities for anti-CD25 (IL2RA) Antibodies

anti-Human CD25 Antibodies:

anti-Rat (Rattus) CD25 Antibodies:

anti-Mouse (Murine) CD25 Antibodies:

All available anti-CD25 Antibodies

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More Antibodies against CD25 Interaction Partners

Human Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. Variation at rs12913965 may affect the risk for shoulder dislocation by affecting the activity of either TICRR or ISG20 (show ISG20 Antibodies).

  2. Through GWAS, we found that emotion dysregulation is associated at genome-wide level significance in a sex-specific manner, with a SNP in IL2RA in men.

  3. it has been shown that CD25 serves as a negative growth regulator of Chronic myeloid leukemia (show BCL11A Antibodies) leukemic stem cells.

  4. study provides evidence that membrane-coated microvesicles released by apoptotic neutrophils suppress a subset of resting Th cells by downregulating IL-2 (show IL2 Antibodies) and IL-2R expression

  5. In T1D, low IL-2 (show IL2 Antibodies) responsiveness was most pronounced in memory T effector cells. Reduced IL-2 (show IL2 Antibodies) responses in memory T effector cells were not rescued by resting, remained lower after activation and proliferation, and were absent in type 2 diabetes.

  6. Decidual stromal cells affect IL-2 (show IL2 Antibodies) production and IL-2R expression and signaling.

  7. The single nucleotide variant rs12722489 determines differential ERalpha (show ESR1 Antibodies) binding and enhancer properties of an IL2RA intronic region.

  8. CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies)

  9. CD4 (show CD4 Antibodies)(+) CD25(+) GARP (show CNGB1 Antibodies)(+) Treg cells are defective in dilated cardiomyopathy patients and GARP (show CNGB1 Antibodies) seems to be a better molecular definition of the regulatory phenotype.

  10. Studies indicate many potential uses of soluble interleukin-2 (show IL2 Antibodies) receptor measurement in the diagnosis and treatment of hemophagocytic syndromes.

Cow (Bovine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. Differential expression of CD25 and IDO (show IDO1 Antibodies) mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. Increase of CD25 expression on bovine neutrophils correlates with mastitis severity in post-partum and early lactating dairy cows.

  3. The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 (show PTGER4 Antibodies) receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells.

  4. There is a positive correlation between the intensity of CD25 expression and the expression of the transcription Foxp3 (show FOXP3 Antibodies) factor in bovine CD8 (show CD8A Antibodies)(+) cells.

  5. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25, CD44 (show CD44 Antibodies), and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

  6. Pretreatment of neonatal PBMC with IL-1beta (show IL1B Antibodies), TNF-alpha (show TNF Antibodies) or IFN-gamma (show IFNG Antibodies) promotes mitogenic response to ConA through up-regulating the production of IL-2 (show IL2 Antibodies) and the expression of the mature IL-2 (show IL2 Antibodies) receptor.

  7. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

Pig (Porcine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. IL2 (show IL2 Antibodies)-R was equally expressed in interfollicular tissue and in follicles, whereas in moderate and severe cases of postweaning multisystemic wasting syndrome, it was detected in interfollicular remnants only

  2. The appearance of CD25 after activation of porcine dendritic cells, is reported.

Mouse (Murine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies). . Pharmacologic inhibition of CDK6 (show CDK6 Antibodies) kinase induces CD25 and RUNX1 (show RUNX1 Antibodies) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.

  2. Combination with anti-programmed cell death protein-1 (PD-1 (show PDCD1 Antibodies)) antibodies promoted complete tumor rejection, indicating the relevance of CD25 antigen as a therapeutic target and promising substrate for future combination approaches in immune-oncology.

  3. Intratesticular inoculation with donor antigens promotes long-term skin allograft survival induced by conventional costimulatory blockade via the induction of both CD8 (show CD8A Antibodies) + CD122 (show IL2RB Antibodies)+ and CD4 (show CD4 Antibodies) + CD25+ Treg cells.

  4. glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 (show IL2 Antibodies) downstream signaling

  5. Expansion of CD25-expressing innate lymhpoid cells by IL-2 (show IL2 Antibodies)/anti-IL-2 (show IL2 Antibodies) complexes leads to a reduction in very low-density lipoprotein cholesterol and atherosclerosis.

  6. our results identify IL-7 (show IL7 Antibodies) as a necessary factor contributing to sustained CD25 expression at Treg surface in vivo thereby affecting their ability to efficiently react to IL-2 (show IL2 Antibodies).

  7. Data indicate that the deletion of interferon-gamma (IFN-gamma (show IFNG Antibodies)) in the CD25 knockout (KO) mice delays glandular destruction and preserves glandular function.

  8. our results suggest that IL-12p40 acts as a negative regulator of autoimmune cholangitis in IL-2Ralpha-/- mice. Compared to IL-2Ralpha-/- mice, p40-/-IL-2Ralpha-/- mice develop liver fibrosis and reduced colitis.

  9. findings indicate a general role for CD25 in contexts where IL-2 (show IL2 Antibodies) signaling is not involved, and may have important implications for all mast cell-related diseases, as well as in all cell types expressing CD25 independently of its IL-2 (show IL2 Antibodies)-related functions.

  10. Functional NK cell repertoires are maintained through IL-2Ralpha and Fas ligand (show FASL Antibodies).

CD25 (IL2RA) Antigen Profile

Antigen Summary

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Alternative names and synonyms associated with CD25 (IL2RA)

  • interleukin 2 receptor, alpha (LOC100222957) antibody
  • interferon stimulated exonuclease gene 20kDa (ISG20) antibody
  • interleukin 2 receptor, alpha (IL2RA) antibody
  • interleukin 2 receptor, alpha (Il2ra) antibody
  • interleukin 2 receptor, alpha chain (Il2ra) antibody
  • CD25 antibody
  • HEM45 antibody
  • IDDM10 antibody
  • IL-2RA antibody
  • Il2r antibody
  • IL2RAC antibody
  • Ly-43 antibody
  • TCGFR antibody

Protein level used designations for IL2RA

interleukin 2 receptor, alpha , estrogen-regulated transcript 45 protein , interferon-stimulated gene 20 kDa protein , promyelocytic leukemia nuclear body-associated protein ISG20 , IL-2 receptor subunit alpha , IL-2-RA , IL-2R subunit alpha , IL2-RA , TAC antigen , interleukin-2 receptor subunit alpha , p55 , IL-2 receptor alpha subunit , IL-2R alpha , cytokine receptor , interleukin-2 receptor alpha chain , interleukin 2 receptor, alpha chain , CD25 antigen , interleukin 2 receptor alpha chain , interleukin-2 receptor alpha subunit , IL-2 Receptor alpha chain , IL-2 alpha receptor , IL2 receptor alpha , interleukin-2 alpha receptor , IL-2R alpha chain , p55 chain

GENE ID SPECIES
100222957 Taeniopygia guttata
3669 Homo sapiens
3559 Homo sapiens
281861 Bos taurus
396814 Sus scrofa
25704 Rattus norvegicus
493953 Felis catus
403870 Canis lupus familiaris
443435 Ovis aries
395294 Gallus gallus
100715332 Cavia porcellus
450884 Pan troglodytes
574300 Macaca mulatta
16184 Mus musculus
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