Browse our anti-CD25 (IL2RA) Antibodies

Full name:
anti-Interleukin 2 Receptor, alpha Antibodies (IL2RA)
On www.antibodies-online.com are 1097 Interleukin 2 Receptor, alpha (IL2RA) Antibodies from 35 different suppliers available. Additionally we are shipping CD25 Kits (81) and CD25 Proteins (53) and many more products for this protein. A total of 1242 CD25 products are currently listed.
Synonyms:
CD25, HEM45, IDDM10, IL-2RA, Il2r, IL2RAC, Ly-43, TCGFR
list all antibodies Gene Name GeneID UniProt
IL2RA 3669 Q96AZ6
IL2RA 25704 P26897
IL2RA 16184 P01590

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All available anti-CD25 Antibodies

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Top referenced anti-CD25 Antibodies

  1. Human Monoclonal CD25 Primary Antibody for Func, FACS - ABIN1106134 : Engert, Martin, Amlot, Wijdenes, Diehl, Thorpe: Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice. in International journal of cancer. Journal international du cancer 1991 (PubMed)
    Show all 18 references for 1106134

  2. Rat (Rattus) Monoclonal CD25 Primary Antibody for EIA, FACS - ABIN120428 : Charteris, Lightman: In vivo lymphokine production in experimental autoimmune uveoretinitis. in Immunology 1993 (PubMed)
    Show all 6 references for 120428

  3. Rat (Rattus) Monoclonal CD25 Primary Antibody for EIA, FACS - ABIN120429 : Barclay: The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. in Immunology 1981 (PubMed)
    Show all 3 references for 120429

  4. Human Polyclonal CD25 Primary Antibody for IF, ELISA - ABIN1531665 : Nikaido, Shimizu, Ishida, Sabe, Teshigawara, Maeda, Uchiyama, Yodoi, Honjo: Molecular cloning of cDNA encoding human interleukin-2 receptor. in Nature 1984 (PubMed)
    Show all 2 references for 1531665

  5. Human Polyclonal CD25 Primary Antibody for IF, ELISA - ABIN1532689 : Bamborough, Hedgecock, Richards: The interleukin-2 and interleukin-4 receptors studied by molecular modelling. in Structure (London, England : 1993) 1995 (PubMed)
    Show all 2 references for 1532689

  6. Human Monoclonal CD25 Primary Antibody for FACS - ABIN1106145 : Sterkers, Baudouin, Ansart-Pirenne, Maisin, Niaudet, Cochat, Loirat: Duration of action of a chimeric interleukin-2 receptor monoclonal antibody, basiliximab, in pediatric kidney transplant recipients. in Transplantation proceedings 2001 (PubMed)
    Show all 2 references for 1106145

  7. Rat (Rattus) Monoclonal CD25 Primary Antibody for FACS - ABIN120430 : Paterson, Jefferies, Green, Brandon, Corthesy, Puklavec, Williams: Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. in Molecular immunology 1988 (PubMed)

  8. Human Monoclonal CD25 Primary Antibody for FACS - ABIN1106144 : Palmer, Farrokh-Siar, Maguire van Seventer, van Seventer: IL-12 decreases activation-induced cell death in human naive Th cells costimulated by intercellular adhesion molecule-1. I. IL-12 alters caspase processing and inhibits enzyme function. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)

  9. Human Monoclonal CD25 Primary Antibody for FACS - ABIN1106146 : Billerbeck, Blum, Thimme: Parallel expansion of human virus-specific FoxP3- effector memory and de novo-generated FoxP3+ regulatory CD8+ T cells upon antigen recognition in vitro. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

More Antibodies against CD25 Interaction Partners

Human Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. The single nucleotide variant rs12722489 determines differential ERalpha (show ESR1 Antibodies) binding and enhancer properties of an IL2RA intronic region.

  2. CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies)

  3. CD4 (show CD4 Antibodies)(+) CD25(+) GARP (show CNGB1 Antibodies)(+) Treg cells are defective in dilated cardiomyopathy patients and GARP (show CNGB1 Antibodies) seems to be a better molecular definition of the regulatory phenotype.

  4. Studies indicate many potential uses of soluble interleukin-2 (show IL2 Antibodies) receptor measurement in the diagnosis and treatment of hemophagocytic syndromes.

  5. Data suggest that differential methylation of the IL2RA promoter in T cells could be an important pathogenic mechanism in multiple sclerosis.

  6. Sustained STAT5 (show STAT5A Antibodies) transcription factor (STAT5 (show STAT5A Antibodies)) phosphorylation is necessary to induce long-term interleukin 2 receptor subunit alpha (CD25) expression in T lymphocytes.

  7. Gastric adenocarcinoma patients present with increased PD-1 (show PDCD1 Antibodies)(+) lymphocytes and CD4 (show CD4 Antibodies)(+)CD25(+)FOXP3 (show FOXP3 Antibodies)(+) regulatory T cells in the peripheral blood.

  8. The serum concentration of soluble IL2 (show IL2 Antibodies) receptor are increased in patients with Kawasaki disease. (Review)

  9. CD25 is an independent prognostic factor in elderly AML (show RUNX1 Antibodies) patients. Alternative therapies for CD25-positive elderly AML (show RUNX1 Antibodies) patients are needed.

  10. The study demonstrated Increased level of CD25 in patients with active vitilligo.

Cow (Bovine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. Differential expression of CD25 and IDO (show IDO1 Antibodies) mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. Increase of CD25 expression on bovine neutrophils correlates with mastitis severity in post-partum and early lactating dairy cows.

  3. The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 (show PTGER4 Antibodies) receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells.

  4. There is a positive correlation between the intensity of CD25 expression and the expression of the transcription Foxp3 (show FOXP3 Antibodies) factor in bovine CD8 (show CD8A Antibodies)(+) cells.

  5. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25, CD44 (show CD44 Antibodies), and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

  6. Pretreatment of neonatal PBMC with IL-1beta (show IL1B Antibodies), TNF-alpha (show TNF Antibodies) or IFN-gamma (show IFNG Antibodies) promotes mitogenic response to ConA through up-regulating the production of IL-2 (show IL2 Antibodies) and the expression of the mature IL-2 (show IL2 Antibodies) receptor.

  7. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

Pig (Porcine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. IL2 (show IL2 Antibodies)-R was equally expressed in interfollicular tissue and in follicles, whereas in moderate and severe cases of postweaning multisystemic wasting syndrome, it was detected in interfollicular remnants only

  2. The appearance of CD25 after activation of porcine dendritic cells, is reported.

Mouse (Murine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

  1. CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies). . Pharmacologic inhibition of CDK6 (show CDK6 Antibodies) kinase induces CD25 and RUNX1 (show RUNX1 Antibodies) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.

  2. Combination with anti-programmed cell death protein-1 (PD-1 (show PDCD1 Antibodies)) antibodies promoted complete tumor rejection, indicating the relevance of CD25 antigen as a therapeutic target and promising substrate for future combination approaches in immune-oncology.

  3. Intratesticular inoculation with donor antigens promotes long-term skin allograft survival induced by conventional costimulatory blockade via the induction of both CD8 (show CD8A Antibodies) + CD122 (show IL2RB Antibodies)+ and CD4 (show CD4 Antibodies) + CD25+ Treg cells.

  4. glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 (show IL2 Antibodies) downstream signaling

  5. Expansion of CD25-expressing innate lymhpoid cells by IL-2 (show IL2 Antibodies)/anti-IL-2 (show IL2 Antibodies) complexes leads to a reduction in very low-density lipoprotein cholesterol and atherosclerosis.

  6. our results identify IL-7 (show IL7 Antibodies) as a necessary factor contributing to sustained CD25 expression at Treg surface in vivo thereby affecting their ability to efficiently react to IL-2 (show IL2 Antibodies).

  7. Data indicate that the deletion of interferon-gamma (IFN-gamma (show IFNG Antibodies)) in the CD25 knockout (KO) mice delays glandular destruction and preserves glandular function.

  8. our results suggest that IL-12p40 acts as a negative regulator of autoimmune cholangitis in IL-2Ralpha-/- mice. Compared to IL-2Ralpha-/- mice, p40-/-IL-2Ralpha-/- mice develop liver fibrosis and reduced colitis.

  9. findings indicate a general role for CD25 in contexts where IL-2 (show IL2 Antibodies) signaling is not involved, and may have important implications for all mast cell-related diseases, as well as in all cell types expressing CD25 independently of its IL-2 (show IL2 Antibodies)-related functions.

  10. Functional NK cell repertoires are maintained through IL-2Ralpha and Fas ligand (show FASL Antibodies).

CD25 (IL2RA) Antigen Profile

Antigen Summary

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Alternative names and synonyms associated with CD25 (IL2RA)

  • interleukin 2 receptor, alpha (LOC100222957) antibody
  • interferon stimulated exonuclease gene 20kDa (ISG20) antibody
  • interleukin 2 receptor, alpha (IL2RA) antibody
  • interleukin 2 receptor, alpha (Il2ra) antibody
  • interleukin 2 receptor, alpha chain (Il2ra) antibody
  • CD25 antibody
  • HEM45 antibody
  • IDDM10 antibody
  • IL-2RA antibody
  • Il2r antibody
  • IL2RAC antibody
  • Ly-43 antibody
  • TCGFR antibody

Protein level used designations for IL2RA

interleukin 2 receptor, alpha , estrogen-regulated transcript 45 protein , interferon-stimulated gene 20 kDa protein , promyelocytic leukemia nuclear body-associated protein ISG20 , IL-2 receptor subunit alpha , IL-2-RA , IL-2R subunit alpha , IL2-RA , TAC antigen , interleukin-2 receptor subunit alpha , p55 , IL-2 receptor alpha subunit , IL-2R alpha , cytokine receptor , interleukin-2 receptor alpha chain , interleukin 2 receptor, alpha chain , CD25 antigen , interleukin 2 receptor alpha chain , interleukin-2 receptor alpha subunit , IL-2 Receptor alpha chain , IL-2 alpha receptor , IL2 receptor alpha , interleukin-2 alpha receptor , IL-2R alpha chain , p55 chain

GENE ID SPECIES
100222957 Taeniopygia guttata
3669 Homo sapiens
3559 Homo sapiens
281861 Bos taurus
396814 Sus scrofa
25704 Rattus norvegicus
493953 Felis catus
403870 Canis lupus familiaris
443435 Ovis aries
395294 Gallus gallus
100715332 Cavia porcellus
450884 Pan troglodytes
574300 Macaca mulatta
16184 Mus musculus
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