CD25 antibody (AA 34-139)

Catalog No. ABIN1845343

This Mouse Monoclonal antibody specifically detects CD25 in WB, IHC, ELISA and IF/ICC. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for CD25 antibody (AA 34-139) (ABIN1845343)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-CD25 Antibody

Binding Specificity: AA 34-139

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: IL2RA

Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor.Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.Mutations in this gene are associated with interleukin 2 receptor alpha deficiency., , , ,.

Molecular Weight: 30.8 kDa

Gene ID: 3559, 16184, 574300

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation