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Browse our FYN Proteins (FYN)

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FYN Oncogene Related To SRC, FGR, YES Proteins (FYN)
On are 9 FYN Oncogene Related To SRC, FGR, YES (FYN) Proteins from 5 different suppliers available. Additionally we are shipping FYN Antibodies (254) and FYN Kits (22) and many more products for this protein. A total of 303 FYN products are currently listed.
AI448320, AW552119, c-fyn, cfyn-a, fyn, im:6908851, p59-FYN, PKC, si:dkey-119m7.5, SLK, SYN, zgc:86720, zgc:109996
list all proteins Gene Name GeneID UniProt
FYN 2534 P06241
FYN 25150 Q62844
FYN 14360 P39688

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FYN Proteins (FYN) by Origin

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More Proteins for FYN Interaction Partners

Zebrafish FYN Oncogene Related To SRC, FGR, YES (FYN) interaction partners

  1. We also show that activation and reduction of Fyn kinase in oligodendrocytes increases and decreases sheath number per cell, respectively.

  2. Yes kinase plays an important role in epiboly and indicate that Yes kinase participates in signaling by focal adhesion kinase during early development.

  3. Fyn kinase plays an important role in epiboly during zebrafish development, possibly through its effects in calcium signaling.

  4. Fyn, and possibly other Src (show SRC Proteins) family members are activated by dephosphorylation of the C-terminal tyrosine at fertilization

  5. investigated signaling pathways in early development by comparison of the phosphoproteome of wild type embryos with Fyn/Yes knockdown embryos that display specific convergence and extension cell movement defects

Human FYN Oncogene Related To SRC, FGR, YES (FYN) interaction partners

  1. Data show that fyn proto-oncogene protein (FYN) expression is deregulated in acute myeloid leukemia (show BCL11A Proteins) and that higher expression of FYN, in combination with FLT3 (show FLT3 Proteins) protein-ITD mutation, resulted in enrichment of the STAT5 (show STAT5A Proteins) transcription factor signaling.

  2. These results indicate that the microenvironment and growth patterns in an multicellular spheroid are complex and require MAPK (show MAPK1 Proteins) and FYN kinase

  3. this study shows that p59(fyn), which is essential for activation of T cells through the T-cell receptor, is also critical for signal transduction through Toll (show TLR4 Proteins)-like receptors in T cells

  4. Fyn expression fluctuated with the progress of normal pregnancy and was elevated in patients with recurrent spontaneous abortion

  5. Neuroendocrine differentiation in prostate cancer cells and visceral metastasis, are least in part, regulated by FYN kinase.

  6. Fyn facilitates mitotic spindle formation through the increase in microtubule polymerization, resulting in the acceleration of M-phase progression.

  7. Results show that three CpG loci within FYN were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 (show PIWIL4 Proteins) and TAOK3 (show TAOK3 Proteins).

  8. Data provide structural insight into the dimerization of Fyn SH2 both in solution and in crystalline conditions, providing novel crystal structures of both the dimer and peptide-bound structures of Fyn SH2.

  9. Mutation of Fyn phosphorylation sites on PIKE (show AGAP2 Proteins)-A, depletion of Fyn, or pharmacological inhibition of Fyn blunts the association between PIKE (show AGAP2 Proteins)-A and AMPK (show PRKAA1 Proteins), resulting in loss of its inhibitory effect on AMPK (show PRKAA1 Proteins).

  10. Results show that Fyn differentially modulates Nav1.5 (show SCN5A Proteins) channel splice variants. It phosphorylates Nav1.5 (show SCN5A Proteins) variants Q-del and Q-pre resulting in there hyperpolarizing and depolarizing shift. Fyn's activity is abolished in the presence of both variants.

Pig (Porcine) FYN Oncogene Related To SRC, FGR, YES (FYN) interaction partners

  1. We conclude that the hypoxia-induced activation of caspase-9 (show CASP9 Proteins) is mediated by Src kinase (show CSK Proteins).

  2. Fyn oncogene (show RAB1A Proteins) alternative spliced forms have been isolated from brain and spleen.

Cow (Bovine) FYN Oncogene Related To SRC, FGR, YES (FYN) interaction partners

  1. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn.

  2. PECAM-1 (show PECAM1 Proteins) and Fyn are essential components of a PECAM-1 (show PECAM1 Proteins)-based mechanosensory complex in endothelial cells.

Mouse (Murine) FYN Oncogene Related To SRC, FGR, YES (FYN) interaction partners

  1. Fyn deficiency alters retinal morphology and adhesion properties of Muller cells. Fyn deficiency parallels a decreased optokinetic response to visual stimuli in vivo.

  2. Fyn mediates high glucose-induced actin cytoskeleton remodeling of podocytes via promoting ROCK activation and paxillin (show PXN Proteins) phosphorylation

  3. MOBP (show MOBP Proteins) synthesis is stimulated by Fyn activity.

  4. Fyn expression was elevated in abortion-prone mice

  5. Fyn facilitates mitotic spindle formation through the increase in microtubule polymerization, resulting in the acceleration of M-phase progression.

  6. Results identified Fyn kinase as a molecular mediator of BDNF signaling that activates Erk1/2 and promotes oligodendrocyte myelination

  7. These results suggest the critical physiological role of TRL4-Fyn interaction in the modulation of PAI-1 (show SERPINE1 Proteins)-tPA (show PLAT Proteins) axis in astrocytes during neuroinflammatory responses such as ischemia/reperfusion injuries.

  8. total levels of ApoER2 (show LRP8 Proteins) and surface levels of ApoER2 (show LRP8 Proteins) are increased by active Fyn

  9. Thy-1 (show THY1 Proteins) facilitates the recruitment of membrane raft-residing signaling molecules such as Fyn kinase and the SFK regulator, Csk binding protein (Cbp (show PAG1 Proteins)), to focal adhesions via its direct coupling of integrins and raft domains.

  10. The SH2 domain of Fyn plays an essential role in Reelin signaling transduction, and an SH2 domain mutant disturbs neuronal migration in a dose-dependent manner.

FYN Protein Profile

Protein Summary

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Alternative names and synonyms associated with FYN

  • FYN oncogene related to SRC, FGR, YES (FYN)
  • FYN oncogene related to SRC, FGR, YES (fyn)
  • FYN oncogene related to SRC, FGR, YES b (fynb)
  • c-fyn protein (fyn)
  • FYN oncogene related to SRC, FGR, YES (Fyn)
  • FYN oncogene related to SRC, FGR, YES a (fyna)
  • Fyn proto-oncogene (Fyn)
  • AI448320 protein
  • AW552119 protein
  • c-fyn protein
  • cfyn-a protein
  • fyn protein
  • im:6908851 protein
  • p59-FYN protein
  • PKC protein
  • si:dkey-119m7.5 protein
  • SLK protein
  • SYN protein
  • zgc:86720 protein
  • zgc:109996 protein

Protein level used designations for FYN

protein-tyrosine kinase fyn , proto-oncogene tyrosine-protein kinase fyn , Fyn non-receptor tyrosine kinase , proto-oncogene c-Fynb , tyrosine-protein kinase fynb , FYN oncogene related to SRC, FGR, YES , proto-oncogene tyrosine-protein kinase fyn-like , tyrosine-protein kinase Fyn-like , p59-Fyn , proto-oncogene c-Fyn , proto-oncogene tyrosine-protein kinase Fyn , tyrosine-protein kinase Fyn , OKT3-induced calcium influx regulator , c-syn protooncogene , proto-oncogene Syn , src-like kinase , src/yes-related novel , tyrosine kinase p59fyn(T) , fyn proto-oncogene , c-fyn, fyn proto-oncogene , protein-tyrosine kinase , proto-oncogene c-Fyna , tyrosine-protein kinase fyna , Src Kinase p59

462944 Pan troglodytes
379812 Xenopus laevis
574214 Macaca mulatta
574422 Danio rerio
100339741 Oryctolagus cuniculus
100439712 Pongo abelii
100585303 Nomascus leucogenys
373609 Xenopus laevis
2534 Homo sapiens
25150 Rattus norvegicus
475032 Canis lupus familiaris
791125 Sus scrofa
527263 Bos taurus
396294 Gallus gallus
373872 Danio rerio
14360 Mus musculus
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