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FYN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FYN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
Catalog No. ABIN2721482
  • Target See all FYN Proteins
    FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 10
    • 3
    • 1
    Human
    Source
    • 5
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FYN protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human FYN (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Biological Activity Comment
    FYN activity verified in a biochemical assay:,FYN activity verified in a biochemical assay:,FYN activity verified in a biochemical assay:
    Top Product
    Discover our top product FYN Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))
    Alternative Name
    Fyn (FYN Products)
    Synonyms
    im:6908851 Protein, si:dkey-119m7.5 Protein, zgc:109996 Protein, c-fyn Protein, cfyn-a Protein, SLK Protein, SYN Protein, p59-FYN Protein, PKC Protein, fyn Protein, zgc:86720 Protein, AI448320 Protein, AW552119 Protein, FYN proto-oncogene, Src family tyrosine kinase Protein, FYN proto-oncogene, Src family tyrosine kinase S homeolog Protein, FYN proto-oncogene, Src family tyrosine kinase b Protein, FYN proto-oncogene, Src family tyrosine kinase L homeolog Protein, FYN proto-oncogene, Src family tyrosine kinase a Protein, Fyn proto-oncogene Protein, FYN Protein, fyn.S Protein, fynb Protein, fyn.L Protein, Fyn Protein, fyna Protein
    Background
    This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
    Molecular Weight
    60.6 kDa
    NCBI Accession
    NP_002028
    Pathways
    JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling
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