Browse our IFNA1 Proteins (IFNA1)

Full name:
Interferon, alpha 1 Proteins (IFNA1)
On are 15 Interferon, alpha 1 (IFNA1) Proteins from 6 different suppliers available. Additionally we are shipping IFNA1 Antibodies (48) and IFNA1 Kits (4) and many more products for this protein. A total of 68 IFNA1 products are currently listed.
Ifa1, IFL, IFN, IFN-ALPHA, IFN-ALPHA-1, IFN-alpha1, IFN-alphaD, IFN1@, IFNA1, IFNA13, IFNA@
list all proteins Gene Name GeneID UniProt
Mouse IFNA1 IFNA1 15962 P01572
IFNA1 298210 P05011
IFNA1 3439 P01562

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IFNA1 Proteins (IFNA1) by Origin

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Top referenced IFNA1 Proteins

  1. Human IFNA1 Protein expressed in Escherichia coli (E. coli) - ABIN1880388 : Asokan, Hua, Young, Gould, Hannan, Kraus, Szakonyi, Grundy, Chen, Crow, Holers: Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for 1880388

More Proteins for IFNA1 Interaction Partners

Atlantic Salmon (Salmo salar) Interferon, alpha 1 (IFNA1) interaction partners

  1. Taken together, this work suggests that IFNa (show IFNA Proteins) provides protection of salmon against SAV3 locally in an infected area while IFNb (show IFNB1 Proteins) and IFNc provides systemic protection against the virus.

  2. IFNa (show IFNA Proteins) is the main IFN subtype induced through salmon RIG-I (show DDX58 Proteins)/viral RNA receptor MDA5 (show IFIH1 Proteins) pathway in lymphoid tissues.

Mouse (Murine) Interferon, alpha 1 (IFNA1) interaction partners

  1. These findings also identify STAT3 (show STAT3 Proteins) as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha (show IFNA Proteins) responsiveness.

  2. the close association between the increased proportion of CD180 (show CD180 Proteins)-negative B cells and the activation of IFN-alpha (show IFNA Proteins) signaling in Systemic lupus erythematosus, is reported.

  3. IL-12 (show IL12A Proteins) and IFN-alpha (show IFNA Proteins) differentially program CD8 (show CD8A Proteins) T cells to re-express distinct levels of PD-1 (show PDCD1 Proteins) upon re-encountering Ag, resulting in IL-12 (show IL12A Proteins)-stimulated cells being less susceptible to exhaustion in the face of sustained tumor Ag.

  4. The expansion of CD8 (show CD8A Proteins) T cells depends on type I IFN, type I IFN and IL-12 (show IL12A Proteins) or is largely independent of the two cytokines.

  5. A spontaneous genomic duplication and frameshift mutation in the guanine exchange factor dedicator of cytokinesis 2 (Dock2) that has arisen in at least a subset of circulating Irf5(-/-) mice and inadvertently been bred to homozygosity.

  6. Knockdown of endogenous guanylate binding protein (GBP)4 (show GBP4 Proteins) increases IRF7 (show IRF7 Proteins)-mediated IFN-alpha (show IFNA Proteins) production, whereas overexpression of GBP4 (show GBP4 Proteins) has the opposite effect.

  7. Data show that similar T cell expansion and serum IgG responses were observed in adenovirus (Adv (show AVIL Proteins))-IFN-treated WT and BAFF (show TNFSF13B Proteins)-deficient mice despite their disparate pathological and clinical responses.

  8. Studies in both mice and humans have demonstrated a role for IFN-alpha (show IFNA Proteins)/beta in directly influencing the fate of both CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells during the initial phases of antigen recognition.

  9. IFN-alpha (show IFNA Proteins) enhances both the induction and maintenance of programmed cell death (PD)-1 (show PDCD1 Proteins) expression on T cell receptor-engaged primary mouse T cells through association of IFN-responsive factor 9 (IRF9 (show IRF9 Proteins)) with the IFN stimulation response element.

  10. This article reports the production of interferon alpha (show IFNA Proteins)/beta (IFN-alpha (show IFNA Proteins)/beta) by SJL/J mouse brain astrocyte cultures infected with Theiler's murine encephalomyelitis virus (TMEV).

Human Interferon, alpha 1 (IFNA1) interaction partners

  1. results demonstrate that Sphingosine 1-phosphate lyase (SPL (show SGPL1 Proteins)) is a host factor that augments type I IFN responses during influenza A virus infection; study delineates the relationship between IKKepsilon (show IKBKE Proteins) and SPL (show SGPL1 Proteins), which provides a mechanistic understanding of the pro-IFN activity of SPL (show SGPL1 Proteins)

  2. These data suggest that plasmacytoid dendritic cells producing IFN-alpha (show IFNA Proteins) and IL-33 (show IL33 Proteins) play a pivotal role in the chronic fibro-inflammatory responses underlying murine autoimmune pancreatitis and human IgG4-related autoimmune pancreatitis.

  3. These findings also identify STAT3 (show STAT3 Proteins) as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha (show IFNA Proteins) responsiveness.

  4. Mothers of children affected by autoimmune congenital heart block had a significantly higher expression IFN-alpha (show IFNA Proteins).

  5. Suppression of the exogenous Type I IFN-induced Jak (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling by NSs might be one of the mechanisms of Severe fever with thrombocytopenia syndrome (SFTS) to evade host immune surveillance.

  6. High Type I Interferon (show IFNA Proteins) expression due to hypomethylation is associated with Systemic Lupus Erythematosus.

  7. these studies identify phosphorylation of S734-STAT2 (show STAT2 Proteins) as a new regulatory mechanism that negatively controls the type I IFN-antiviral response.

  8. The synthetic IFNP molecule exerted its antitumor activity by upregulating the downstream genes involved in the STAT1 (show STAT1 Proteins) pathway and in apoptosis. Using a cell receptor binding assay, we showed that this Jurkat-binding peptide (show HP Proteins) facilitated the binding affinity of IFNalpha to the cell surface type I IFN receptor

  9. KSHV-encoded viral IRF4 (show IRF4 Proteins) interacts with the host IRF7 (show IRF7 Proteins) and inhibits interferon-alpha (show IFNA Proteins) production.

  10. Data indicate ARID3a (show ARID3A Proteins)(+) B cells as a type of effector B cell, and link ARID3a (show ARID3A Proteins) expression in B lymphocytes to interferon alpha (IFNa (show IFNA Proteins))-associated inflammatory responses in systemic lupus erythematosus (SLE).

Pig (Porcine) Interferon, alpha 1 (IFNA1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (show IFNA Proteins) response by inducing STAT1 (show STAT1 Proteins) degradation.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 (show IRF3 Proteins) and subsequent degradation of IRF-3 (show IRF3 Proteins), leading to downregulation of IFN-alpha (show IFNA Proteins)/beta production.

  3. Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29.

  4. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (show IFNA Proteins)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (show IFNA Proteins) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

  5. Nsp1beta inhibits interferon-activated (show MNDA Proteins) STAT1 (show STAT1 Proteins)/STAT2 (show STAT2 Proteins) signal transduction by inducing karyopherin-alpha1 degradation.

  6. Expression of Mx protein (show MX2 Proteins) and interferon-alpha (IFN-alpha (show IFNA Proteins)) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.

  7. Foot-and-Mouth Disease Virus inhibits IFN-alpha (show IFNA Proteins) expression in infected cells by blocking cap-dependent translation.

IFNA1 Protein Profile

Protein Summary

The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted.

Alternative names and synonyms associated with IFNA1

  • interferon alpha 1 (IFNA1)
  • interferon-alpha-1 (IFNA1)
  • interferon alpha 1 (ifna1)
  • interferon, alpha 13 (IFNA13)
  • interferon alpha 1 (Ifna1)
  • interferon alpha-1-like (LOC100629951)
  • Interferon alpha-1-like (LOC616272)
  • interferon-alpha 1 (Ifna1)
  • interferon, alpha 1 (IFNA1)
  • Ifa1 protein
  • IFL protein
  • IFN protein
  • IFN-ALPHA protein
  • IFN-ALPHA-1 protein
  • IFN-alpha1 protein
  • IFN-alphaD protein
  • IFN1@ protein
  • IFNA1 protein
  • IFNA13 protein
  • IFNA@ protein

Protein level used designations for Interferon, alpha 1 Proteins (IFNA1)

interferon alpha-1/13 , interferon-alpha-1 , interferon alpha 1 , interferon-alpha-3 , interferon alpha 13 , IFN-alpha-1 , interferon alpha family gene 1 , interferon alpha-1 , IFN-alpha 1 , interferon-alpha 1 , IFN-alpha 1b , IFN-alpha-1/13 , interferon alpha 1b , interferon alpha-D , interferon-alpha1 , leIF D , IFN-alpha-6 , interferon-alpha-6

493765 Felis catus
100053022 Equus caballus
100137019 Salmo salar
493654 Felis catus
15962 Mus musculus
100629951 Equus caballus
616272 Bos taurus
298210 Rattus norvegicus
3439 Homo sapiens
397686 Sus scrofa
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