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Browse our IFNA1 Proteins (IFNA1)

Full name:
Interferon, alpha 1 Proteins (IFNA1)
On are 13 Interferon, alpha 1 (IFNA1) Proteins from 6 different suppliers available. Additionally we are shipping IFNA1 Antibodies (42) and IFNA1 Kits (4) and many more products for this protein. A total of 60 IFNA1 products are currently listed.
Ifa1, IFL, IFN, IFN-ALPHA, IFN-ALPHA-1, IFN-alpha1, IFN-alphaD, IFN1@, IFNA1, IFNA13, IFNA@
list all proteins Gene Name GeneID UniProt
Mouse IFNA1 IFNA1 15962 P01572
IFNA1 298210 P05011
IFNA1 3439 P01562

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IFNA1 Proteins (IFNA1) by Origin

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Top referenced IFNA1 Proteins

  1. Human IFNA1 Protein expressed in Escherichia coli (E. coli) - ABIN1880388 : Asokan, Hua, Young, Gould, Hannan, Kraus, Szakonyi, Grundy, Chen, Crow, Holers: Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for ABIN1880388

More Proteins for IFNA1 Interaction Partners

Atlantic Salmon (Salmo salar) Interferon, alpha 1 (IFNA1) interaction partners

  1. Taken together, this work suggests that IFNa (show IFNA Proteins) provides protection of salmon against SAV3 locally in an infected area while IFNb (show IFNB1 Proteins) and IFNc provides systemic protection against the virus.

  2. IFNa (show IFNA Proteins) is the main IFN subtype induced through salmon RIG-I (show DDX58 Proteins)/viral RNA receptor MDA5 (show IFIH1 Proteins) pathway in lymphoid tissues.

Mouse (Murine) Interferon, alpha 1 (IFNA1) interaction partners

  1. IL-12 (show IL12A Proteins) and IFN-alpha (show IFNA Proteins) differentially program CD8 (show CD8A Proteins) T cells to re-express distinct levels of PD-1 (show PDCD1 Proteins) upon re-encountering Ag, resulting in IL-12 (show IL12A Proteins)-stimulated cells being less susceptible to exhaustion in the face of sustained tumor Ag.

  2. The expansion of CD8 (show CD8A Proteins) T cells depends on type I IFN, type I IFN and IL-12 (show IL12A Proteins) or is largely independent of the two cytokines.

  3. A spontaneous genomic duplication and frameshift mutation in the guanine exchange factor dedicator of cytokinesis 2 (Dock2) that has arisen in at least a subset of circulating Irf5(-/-) mice and inadvertently been bred to homozygosity.

  4. Knockdown of endogenous guanylate binding protein (GBP)4 (show GBP4 Proteins) increases IRF7 (show IRF7 Proteins)-mediated IFN-alpha (show IFNA Proteins) production, whereas overexpression of GBP4 (show GBP4 Proteins) has the opposite effect.

  5. Data show that similar T cell expansion and serum IgG responses were observed in adenovirus (Adv (show AVIL Proteins))-IFN-treated WT and BAFF (show TNFSF13B Proteins)-deficient mice despite their disparate pathological and clinical responses.

  6. Studies in both mice and humans have demonstrated a role for IFN-alpha (show IFNA Proteins)/beta in directly influencing the fate of both CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells during the initial phases of antigen recognition.

  7. IFN-alpha (show IFNA Proteins) enhances both the induction and maintenance of programmed cell death (PD)-1 (show PDCD1 Proteins) expression on T cell receptor-engaged primary mouse T cells through association of IFN-responsive factor 9 (IRF9 (show IRF9 Proteins)) with the IFN stimulation response element.

  8. This article reports the production of interferon alpha (show IFNA Proteins)/beta (IFN-alpha (show IFNA Proteins)/beta) by SJL/J mouse brain astrocyte cultures infected with Theiler's murine encephalomyelitis virus (TMEV).

  9. TLR ligands facilitate antibody response by inducing type I interferon (show IFNA Proteins) (IFN), which in turn elicits rapid and significant amounts of antigen-specific IgG2c.

  10. These results demonstrate that mouse hepatitis virus is recognized by both RIG-I (show DDX58 Proteins) and MDA5 (show IFIH1 Proteins) and induces IFN-alpha (show IFNA Proteins)/beta through the activation of the IRF-3 (show IRF3 Proteins) signaling pathway.

Human Interferon, alpha 1 (IFNA1) interaction partners

  1. KSHV-encoded viral IRF4 (show IRF4 Proteins) interacts with the host IRF7 (show IRF7 Proteins) and inhibits interferon-alpha (show IFNA Proteins) production.

  2. Data indicate ARID3a (show ARID3A Proteins)(+) B cells as a type of effector B cell, and link ARID3a (show ARID3A Proteins) expression in B lymphocytes to interferon alpha (IFNa (show IFNA Proteins))-associated inflammatory responses in systemic lupus erythematosus (SLE).

  3. On one hand, hepatitis B virus activates MMP-9 (show MMP9 Proteins) in infected patients and leukocytes. On the other hand, MMP-9 (show MMP9 Proteins) facilitates hepatitis B virus replication through repressing IFN/JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling, IFNAR1 (show IFNAR1 Proteins) function, and IFN-alpha (show IFNA Proteins) action.

  4. Interferon-alpha (show IFNA Proteins) Induces the apoptosis of Hela cells by activating both the intrinsic mitochondrial pathway and endoplasmic reticulum stress-induced pathway.

  5. Decreased interferon alpha (IFN-alpha (show IFNA Proteins)) secretion induced by Toll-like receptor 7 (show TLR7 Proteins) and Toll-like receptor 8 (show TLR8 Proteins) (TLR7 (show TLR7 Proteins)/TLR8 (show TLR8 Proteins)) activation was observed in common variable immunodeficiency (CVID (show TNFRSF13B Proteins)), which was recovered with Toll-like receptor 9 (TLR9 (show TLR9 Proteins)) signaling.

  6. Plasmacytoid dendritic cells (pDCs) and type 1 interferon (show IFNA Proteins) (FNalpha/beta)frequently accompanied plasmablast/plasma cells (PB/PCs).

  7. These results establish that activation of STAT (show STAT1 Proteins) pathway is essential for anti-hepatitis c virus efficacy of IFN-alpha (show IFNA Proteins).

  8. IL-2 (show IL2 Proteins) therapy should be used as a first- or second-line therapy following IFN-a (show IFNA6 Proteins) therapy. IL-2 (show IL2 Proteins) may have a lower response if it is used after molecular-targeted therapy or other treatments

  9. results show that IFNA1 rs1332190 and IFNA17 (show IFNa17 Proteins) rs9298814 SNPs may play an important role in Crimean-Congo hemorrhagic fever susceptibility

  10. Interferon-alpha (show IFNA Proteins)-induced TRIM22 (show TRIM22 Proteins) interrupts hepatitis c virus replication by ubiquitinating NS5A.

Pig (Porcine) Interferon, alpha 1 (IFNA1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (show IFNA Proteins) response by inducing STAT1 (show STAT1 Proteins) degradation.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 (show IRF3 Proteins) and subsequent degradation of IRF-3 (show IRF3 Proteins), leading to downregulation of IFN-alpha (show IFNA Proteins)/beta production.

  3. Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29.

  4. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (show IFNA Proteins)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (show IFNA Proteins) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

  5. Nsp1beta inhibits interferon-activated (show MNDA Proteins) STAT1 (show STAT1 Proteins)/STAT2 (show STAT2 Proteins) signal transduction by inducing karyopherin-alpha1 degradation.

  6. Expression of Mx protein (show MX2 Proteins) and interferon-alpha (IFN-alpha (show IFNA Proteins)) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.

  7. Foot-and-Mouth Disease Virus inhibits IFN-alpha (show IFNA Proteins) expression in infected cells by blocking cap-dependent translation.

IFNA1 Protein Profile

Protein Summary

The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted.

Alternative names and synonyms associated with IFNA1

  • interferon alpha 1 (IFNA1)
  • interferon-alpha-1 (IFNA1)
  • interferon alpha 1 (ifna1)
  • interferon, alpha 13 (IFNA13)
  • interferon alpha 1 (Ifna1)
  • interferon alpha-1-like (LOC100629951)
  • Interferon alpha-1-like (LOC616272)
  • interferon-alpha 1 (Ifna1)
  • interferon, alpha 1 (IFNA1)
  • Ifa1 protein
  • IFL protein
  • IFN protein
  • IFN-ALPHA protein
  • IFN-ALPHA-1 protein
  • IFN-alpha1 protein
  • IFN-alphaD protein
  • IFN1@ protein
  • IFNA1 protein
  • IFNA13 protein
  • IFNA@ protein

Protein level used designations for Interferon, alpha 1 Proteins (IFNA1)

interferon alpha-1/13 , interferon-alpha-1 , interferon alpha 1 , interferon-alpha-3 , interferon alpha 13 , IFN-alpha-1 , interferon alpha family gene 1 , interferon alpha-1 , IFN-alpha 1 , interferon-alpha 1 , IFN-alpha 1b , IFN-alpha-1/13 , interferon alpha 1b , interferon alpha-D , interferon-alpha1 , leIF D , IFN-alpha-6 , interferon-alpha-6

493765 Felis catus
100053022 Equus caballus
100137019 Salmo salar
493654 Felis catus
15962 Mus musculus
100629951 Equus caballus
616272 Bos taurus
298210 Rattus norvegicus
3439 Homo sapiens
397686 Sus scrofa
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