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IFNA1 Protein (AA 24-189) (Fc Tag)

IFNA1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7274851
  • Target See all IFNA1 Proteins
    IFNA1 (Interferon, alpha 1 (IFNA1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-189
    Origin
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IFNA1 protein is labelled with Fc Tag.
    Purpose
    Mouse IFN alpha 1 Protein
    Sequence
    Cys24-Lys189
    Characteristics
    Recombinant Mouse IFN alpha 1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Cys24-Lys189.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IFNA1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IFNA1 (Interferon, alpha 1 (IFNA1))
    Alternative Name
    IFN alpha 1 (IFNA1 Products)
    Synonyms
    IFL Protein, IFN Protein, IFN-ALPHA Protein, IFN-alphaD Protein, IFNA13 Protein, IFNA@ Protein, Ifa1 Protein, IFN-ALPHA-1 Protein, IFN1@ Protein, IFNA1 Protein, IFN-alpha Protein, IFN-gamma Protein, IFNA Protein, IFNA2 Protein, IFNA6 Protein, IFN-alpha1 Protein, interferon alpha 13 Protein, interferon alpha 1 Protein, interferon, alpha 1 Protein, interferon, alpha 13 Protein, interferon Protein, interferon-alpha 1 Protein, interferon, alpha, leukocyte Protein, interferon-alpha-14 Protein, IFNA13 Protein, IFNA1 Protein, Ifna1 Protein, ifna1 Protein, IFNA3 Protein, IFN-ALPHA-14 Protein
    Background
    IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes.
    Molecular Weight
    45.88 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    UniProt
    P01572
    Pathways
    JAK-STAT Signaling, Hepatitis C
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