Browse our anti-IL-6 Receptor (IL6R) Antibodies

Full name:
anti-Interleukin-6 Receptor Antibodies (IL6R)
On are 302 Interleukin-6 Receptor (IL6R) Antibodies from 30 different suppliers available. Additionally we are shipping IL-6 Receptor Kits (62) and IL-6 Receptor Proteins (58) and many more products for this protein. A total of 440 IL-6 Receptor products are currently listed.
CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL-6Ralpha, IL6Q, Il6r, IL6R1, Il6ra, IL6RQ
list all antibodies Gene Name GeneID UniProt
IL6R 3570 P08887
IL6R 24499  
IL6R 16194 P22272

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All available anti-IL-6 Receptor Antibodies

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Top referenced anti-IL-6 Receptor Antibodies

  1. Human Monoclonal IL-6 Receptor Primary Antibody for ELISA (Capture), FACS - ABIN4899503 : Hurst, Wilkinson, McLoughlin, Jones, Horiuchi, Yamamoto, Rose-John, Fuller, Topley, Jones: Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. in Immunity 2001 (PubMed)
    Show all 15 references for 4899503

  2. Mouse (Murine) Polyclonal IL-6 Receptor Primary Antibody for ELISA (Capture), FACS - ABIN4899510 : Chalaris, Rabe, Paliga, Lange, Laskay, Fielding, Jones, Rose-John, Scheller: Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. in Blood 2007 (PubMed)
    Show all 6 references for 4899510

  3. Human Monoclonal IL-6 Receptor Primary Antibody for ELISA, WB - ABIN395681 : Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). in American journal of obstetrics and gynecology 2010 (PubMed)
    Show all 5 references for 395681

  4. Human Monoclonal IL-6 Receptor Primary Antibody for EIA, FACS - ABIN1105828 : Labbozzetta, Notarbartolo, Poma, Giannitrapani, Cervello, Montalto, DAlessandro: Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma. in Annals of the New York Academy of Sciences 2007 (PubMed)
    Show all 4 references for 1105828

  5. Human Monoclonal IL-6 Receptor Primary Antibody for Func, IHC (fro) - ABIN1105829 : Dubois, Barthélémy, Durand, Liu, Caux, Brière: Toward a role of dendritic cells in the germinal center reaction: triggering of B cell proliferation and isotype switching. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 3 references for 1105829

  6. Human Monoclonal IL-6 Receptor Primary Antibody for Func, EIA - ABIN1105827 : Larregina, Morelli, Kolkowski, Sanjuan, Barboza, Fainboim: Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants. in Immunology 1997 (PubMed)
    Show all 2 references for 1105827

  7. Human Monoclonal IL-6 Receptor Primary Antibody for FACS - ABIN4896216 : Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011 (PubMed)

  8. Human Monoclonal IL-6 Receptor Primary Antibody for EIA, FACS - ABIN1105833 : Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: STAT3 is constitutively activated in Hodgkin cell lines. in Blood 2001 (PubMed)

  9. Human Monoclonal IL-6 Receptor Primary Antibody for IHC (fro), FACS - ABIN1105830 : Hess, Smola, Sandaradura De Silva, Hadaschik, Kube, Baldus, Flucke, Pfister: Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)

  10. Mouse (Murine) Polyclonal IL-6 Receptor Primary Antibody for ELISA, WB - ABIN2000701 : Stauber, Barill, Stauber, Miller: Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females. in Clinical physiology (Oxford, England) 2000 (PubMed)

More Antibodies against IL-6 Receptor Interaction Partners

Zebrafish Interleukin-6 Receptor (IL6R) interaction partners

  1. The expression of IL-6 (show IL6 PLURAL_@2410@), IL-6R and gp130 (show IL6ST PLURAL_@2410@) transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.

Human Interleukin-6 Receptor (IL6R) interaction partners

  1. Data show that the let-7c/miR (show MLXIP Antibodies)-99a/miR (show MLXIP Antibodies)-125b cluster controlled tumorigenesis by targeting IL-6 (show IL6 Antibodies), IL-6R and IGF1R (show IGF1R Antibodies).

  2. Our results argued that increased expression of sIL6R from myeloid cells and subsequent c-Maf (show MAF Antibodies) induction were adverse events for counteracting tumor-specific Th1 (show TH1L Antibodies) generation. Overall, this work provides a mechanistic rationale for sIL6R targeting to improve the efficacy of T-cell-mediated cancer immunotherapy

  3. These results demonstrate a novel physiologic role for a disintegrin and metalloprotease 17 (show ADAM17 Antibodies) in regulating murine IL-6 (show IL6 Antibodies) signals during inflammatory processes.

  4. this study show that soluble IL-6R is infiltrating from the circulation in an ADAM17 (show ADAM17 Antibodies)-independent process and is involved in the controlled resolution of an acute inflammatory episode

  5. the sIL (show PMEL Antibodies)-6R/p28 (show PSMD10 Antibodies) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (show AFT1 Antibodies) to the IFN-lambda1 promoter via the p38 MAPK (show MAPK14 Antibodies) signaling pathway; results demonstrate the important role of sIL (show PMEL Antibodies)-6R/p28 (show PSMD10 Antibodies) FP in mediating virus-induced type III IFN production

  6. Thus, trans-signaling of IL-6 (show IL6 Antibodies) can only occur via sIL (show PMEL Antibodies)-6R, but not sCD5 (show SCD5 Antibodies).

  7. The here presented data demonstrate that miR (show MLXIP Antibodies)-451 may function as a potential suppressor of tumor growth, migration and angiogenesis in osteosarcoma via down-regulating IL 6R.

  8. DNA hypomethylation of IL-6 (show IL6 Antibodies) gene measured in blood leukocytes was associated with increased risk of ischemic heart disease.

  9. DNA hypomethylation of IL-6 (show IL6 Antibodies) gene measured in blood leukocytes was associated with increased risk of ischemic heart disease.

  10. minor allele, with the difference eliminated upon addition of tocilizumab. In conclusion, there is evidence that neutrophils may be an important source of sIL (show PMEL Antibodies)-6R in the lungs, and the Asp358Ala variant may have pro-inflammatory effects in lung cells.d However, we were unable to identify evidence for aisease

Pig (Porcine) Interleukin-6 Receptor (IL6R) interaction partners

  1. IL-6sR and gp130 (show ANPEP PLURAL_@2410@), but not IL-6R alpha, play important roles in regulation of granulosa cell survival

Cow (Bovine) Interleukin-6 Receptor (IL6R) interaction partners

  1. Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF Antibodies) and IL-6 (show IL6 Antibodies)/sIL (show STIL Antibodies)-6R in causing proteoglycan (show Vcan Antibodies) degradation in human and bovine cartilage.

Mouse (Murine) Interleukin-6 Receptor (IL6R) interaction partners

  1. TNF (show TNF Antibodies)/IL-6 (show IL6 Antibodies) generated osteoclasts in vitro that resorbed mineralized tissue through a pathway dependent on IL-6R, NFATc1 (show NFATC1 Antibodies), DNAX-activation protein 12 (show TYROBP Antibodies), and cell proliferation

  2. C2C12 myotubes possesses a mechanism for regulating IL-6R and gp130 (show LRPPRC PLURAL_@2410@) expression following lipoic acid treatment or heat shock.

  3. Interleukin-6 receptor alpha may have a role in skin lesions in a murine model of systemic lupus erythematosus

  4. findings identify TRAF3 (show TRAF3 Antibodies) and PTPN22 (show PTPN22 Antibodies) as inhibitors of IL-6R signaling in B cells and reveal a previously uncharacterized role for TRAF3 (show TRAF3 Antibodies) in the regulation of plasma cell differentiation

  5. Data show that blockade of interleukin-6 receptor by an anti-IL-6R antibody can augment the anti-arthritic effect of glucocorticoids (GCs (show UGCG Antibodies)) and inhibit the bone loss they cause.

  6. established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 Antibodies) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10 (show ADAM10 Antibodies)

  7. Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung

  8. When endogenously released IL-6 (show IL6 Antibodies) binds to Il-6Ralpha in brain the effect is pyrogenic.

  9. metastasizing cancer cells induced higher MDSCs infiltration and prompted them to secret exaggerated IL-6 (show IL6 Antibodies) as well as soluble IL-6Ra, which, in turn, triggered a persistent increase of pSTAT3 in tumor cells.

  10. Cellular senescence or EGFR (show EGFR Antibodies) signaling induces Interleukin 6 receptor expression controlled by mTOR (show FRAP1 Antibodies).

IL-6 Receptor (IL6R) Antigen Profile

Antigen Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Alternative names and synonyms associated with IL-6 Receptor (IL6R)

  • interleukin 6 receptor (IL6R) antibody
  • interleukin 6 receptor (il6r) antibody
  • interleukin 6 receptor (Il6r) antibody
  • interleukin 6 receptor-like (LOC100347752) antibody
  • interleukin 6 receptor, alpha (Il6ra) antibody
  • CD126 antibody
  • gp80 antibody
  • IL-6R antibody
  • IL-6R-1 antibody
  • IL-6RA antibody
  • IL-6Ralpha antibody
  • IL6Q antibody
  • Il6r antibody
  • IL6R1 antibody
  • Il6ra antibody
  • IL6RQ antibody

Protein level used designations for IL6R

interleukin 6 receptor , interleukin 6 receptor alpha , interleukin-6 receptor subunit alpha , CD126 antigen , IL-6 receptor subunit alpha , IL-6R 1 , membrane glycoprotein 80 , IL-6R subunit alpha , IL-6R-alpha , IL-6RA , interleukin 6 receptor, alpha , IL-6 receptor alpha chain

469506 Pan troglodytes
100135755 Danio rerio
3570 Homo sapiens
24499 Rattus norvegicus
101085689 Felis catus
399522 Sus scrofa
612271 Canis lupus familiaris
507359 Bos taurus
100730490 Cavia porcellus
101103369 Ovis aries
100347752 Oryctolagus cuniculus
16194 Mus musculus
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