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Browse our anti-IL-6 Receptor (IL6R) Antibodies

Full name:
anti-Interleukin-6 Receptor Antibodies (IL6R)
On are 254 Interleukin-6 Receptor (IL6R) Antibodies from 29 different suppliers available. Additionally we are shipping IL-6 Receptor Kits (57) and IL-6 Receptor Proteins (53) and many more products for this protein. A total of 381 IL-6 Receptor products are currently listed.
CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL-6Ralpha, IL6Q, Il6r, IL6R1, Il6ra, IL6RQ
list all antibodies Gene Name GeneID UniProt
IL6R 3570 P08887
IL6R 24499  
IL6R 16194 P22272

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Most Popular Reactivities for anti-IL-6 Receptor (IL6R) Antibodies

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anti-Human IL-6 Receptor Antibodies:

anti-Rat (Rattus) IL-6 Receptor Antibodies:

anti-Mouse (Murine) IL-6 Receptor Antibodies:

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Top referenced anti-IL-6 Receptor Antibodies

  1. Human Monoclonal IL-6 Receptor Primary Antibody for ELISA (Capture), FACS - ABIN4899503 : Hurst, Wilkinson, McLoughlin, Jones, Horiuchi, Yamamoto, Rose-John, Fuller, Topley, Jones: Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. in Immunity 2001 (PubMed)
    Show all 15 references for ABIN4899503

  2. Mouse (Murine) Polyclonal IL-6 Receptor Primary Antibody for ELISA (Capture), FACS - ABIN4899510 : Chalaris, Rabe, Paliga, Lange, Laskay, Fielding, Jones, Rose-John, Scheller: Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. in Blood 2007 (PubMed)
    Show all 6 references for ABIN4899510

  3. Human Monoclonal IL-6 Receptor Primary Antibody for ELISA, WB - ABIN395681 : Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). in American journal of obstetrics and gynecology 2010 (PubMed)
    Show all 5 references for ABIN395681

  4. Human Monoclonal IL-6 Receptor Primary Antibody for EIA, FACS - ABIN1105828 : Labbozzetta, Notarbartolo, Poma, Giannitrapani, Cervello, Montalto, DAlessandro: Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma. in Annals of the New York Academy of Sciences 2007 (PubMed)
    Show all 4 references for ABIN1105828

  5. Human Monoclonal IL-6 Receptor Primary Antibody for Func, IHC (fro) - ABIN1105829 : Dubois, Barthélémy, Durand, Liu, Caux, Brière: Toward a role of dendritic cells in the germinal center reaction: triggering of B cell proliferation and isotype switching. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 3 references for ABIN1105829

  6. Human Monoclonal IL-6 Receptor Primary Antibody for Func, EIA - ABIN1105827 : Larregina, Morelli, Kolkowski, Sanjuan, Barboza, Fainboim: Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants. in Immunology 1997 (PubMed)
    Show all 2 references for ABIN1105827

  7. Mouse (Murine) Polyclonal IL-6 Receptor Primary Antibody for ELISA, WB - ABIN2000701 : Stauber, Barill, Stauber, Miller: Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females. in Clinical physiology (Oxford, England) 2000 (PubMed)

  8. Human Monoclonal IL-6 Receptor Primary Antibody for FACS - ABIN4896216 : Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. in Journal of thrombosis and haemostasis : JTH 2011 (PubMed)

  9. Human Monoclonal IL-6 Receptor Primary Antibody for IHC (fro), FACS - ABIN1105830 : Hess, Smola, Sandaradura De Silva, Hadaschik, Kube, Baldus, Flucke, Pfister: Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)

  10. Human Monoclonal IL-6 Receptor Primary Antibody for EIA, FACS - ABIN1105833 : Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: STAT3 is constitutively activated in Hodgkin cell lines. in Blood 2001 (PubMed)

More Antibodies against IL-6 Receptor Interaction Partners

Zebrafish Interleukin-6 Receptor (IL6R) interaction partners

  1. The expression of IL-6 (show IL6 Antibodies), IL-6R and gp130 (show IL6ST Antibodies) transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.

Human Interleukin-6 Receptor (IL6R) interaction partners

  1. MiR-451 may function as a potential suppressor of tumor angiogenesis in HCC by targeting IL-6R-STAT3-VEGF signaling, suggesting.

  2. miR (show MLXIP Antibodies)-106a promoted the growth and invasion of SKOV3 cells by targeting phosphatase and tensin homolog (PTEN (show PTEN Antibodies)). Furthermore, the present study revealed that IL-6 (show IL6 Antibodies) inhibited miR (show MLXIP Antibodies)-106a expression by activating STAT3 (show STAT3 Antibodies). Tocilizumab, a humanized anti-human IL-6R antibody, that competitively inhibits IL-6 (show IL6 Antibodies)/IL-6R signaling, did not inhibit the proliferation and invasion of SKOV3 cells.

  3. No significant association between IL6R rs2228145 and dementia.

  4. we evaluated anti-IL-6 (show IL6 Antibodies) receptor antibody treatment of cancer-related anemia in an IL-6 (show IL6 Antibodies)-producing human lung cancer xenograft model.We demonstrated that inhibition of the IL-6 (show IL6 Antibodies) signaling pathway by MR16-1 treatment resulted in significant recovery of iron-deficiency anemia and alleviation of cancer-related symptoms

  5. Data suggest domains D1-D3, which contain cytokine binding module, determine which cytokine can activate interleukin-6 (show IL6 Antibodies) or interleukin-11 (show IL11 Antibodies) alpha-receptor subunits; stalk, transmembrane, or intracellular regions do not participate in ligand selectivity.

  6. Anti-IL-6R antibody prevented the early loss of intrahepatic islet grafts mediated by HMGB1 (show HMGB1 Antibodies)-induced immune activation after islet transplantation.

  7. While prior studies have found an association between PDE4D (show PDE4D Antibodies) and IL6R polymorphisms and ischemic stroke, the results of this study suggest that this association may be different in a hypertensive population.

  8. Authors identified miR (show MLXIP Antibodies)-125a as a direct regulator of IL-6R, and the genotype of rs12976445 might be a novel predictor of the development of DN in DM.

  9. This is the first study to investigate the effects of functional two polymorphisms on IL-6 (show IL6 Antibodies) and IL-6R genes in a pediatric patient group with AA risk.

  10. results provide evidence that two IL6R gene polymorphisms rs2228145 C and rs12083537 G are associated with poor lung function in patients with asthma. Furthermore, the rs2228145 A-C variant is associated with levels of sIL-6R and IgE.

Pig (Porcine) Interleukin-6 Receptor (IL6R) interaction partners

  1. IL-6sR and gp130 (show ANPEP Antibodies), but not IL-6R alpha, play important roles in regulation of granulosa cell survival

Cow (Bovine) Interleukin-6 Receptor (IL6R) interaction partners

  1. Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF Antibodies) and IL-6 (show IL6 Antibodies)/sIL (show STIL Antibodies)-6R in causing proteoglycan (show Vcan Antibodies) degradation in human and bovine cartilage.

Mouse (Murine) Interleukin-6 Receptor (IL6R) interaction partners

  1. C2C12 myotubes possesses a mechanism for regulating IL-6R and gp130 (show LRPPRC Antibodies) expression following lipoic acid treatment or heat shock.

  2. Interleukin-6 receptor alpha may have a role in skin lesions in a murine model of systemic lupus erythematosus

  3. findings identify TRAF3 (show TRAF3 Antibodies) and PTPN22 (show PTPN22 Antibodies) as inhibitors of IL-6R signaling in B cells and reveal a previously uncharacterized role for TRAF3 (show TRAF3 Antibodies) in the regulation of plasma cell differentiation

  4. Data show that blockade of interleukin-6 receptor by an anti-IL-6R antibody can augment the anti-arthritic effect of glucocorticoids (GCs (show UGCG Antibodies)) and inhibit the bone loss they cause.

  5. established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 Antibodies) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10 (show ADAM10 Antibodies)

  6. Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung

  7. When endogenously released IL-6 (show IL6 Antibodies) binds to Il-6Ralpha in brain the effect is pyrogenic.

  8. metastasizing cancer cells induced higher MDSCs infiltration and prompted them to secret exaggerated IL-6 (show IL6 Antibodies) as well as soluble IL-6Ra, which, in turn, triggered a persistent increase of pSTAT3 in tumor cells.

  9. Cellular senescence or EGFR (show EGFR Antibodies) signaling induces Interleukin 6 receptor expression controlled by mTOR (show FRAP1 Antibodies).

  10. IL-6Ralpha deficiency activates PP-1alpha and Mule expression, resulting in increased Mcl-1 (show MCL1 Antibodies) turnover and protection against HCC (show FAM126A Antibodies) development.

IL-6 Receptor (IL6R) Antigen Profile

Antigen Summary

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Alternative names and synonyms associated with IL-6 Receptor (IL6R)

  • interleukin 6 receptor (IL6R) antibody
  • interleukin 6 receptor (il6r) antibody
  • interleukin 6 receptor (Il6r) antibody
  • interleukin 6 receptor-like (LOC100347752) antibody
  • interleukin 6 receptor, alpha (Il6ra) antibody
  • CD126 antibody
  • gp80 antibody
  • IL-6R antibody
  • IL-6R-1 antibody
  • IL-6RA antibody
  • IL-6Ralpha antibody
  • IL6Q antibody
  • Il6r antibody
  • IL6R1 antibody
  • Il6ra antibody
  • IL6RQ antibody

Protein level used designations for IL6R

interleukin 6 receptor , interleukin 6 receptor alpha , interleukin-6 receptor subunit alpha , CD126 antigen , IL-6 receptor subunit alpha , IL-6R 1 , membrane glycoprotein 80 , IL-6R subunit alpha , IL-6R-alpha , IL-6RA , interleukin 6 receptor, alpha , IL-6 receptor alpha chain

469506 Pan troglodytes
100135755 Danio rerio
3570 Homo sapiens
24499 Rattus norvegicus
101085689 Felis catus
399522 Sus scrofa
612271 Canis lupus familiaris
507359 Bos taurus
100730490 Cavia porcellus
101103369 Ovis aries
100347752 Oryctolagus cuniculus
16194 Mus musculus
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