IL-6 Receptor antibody (AA 21-120)

Catalog No. ABIN561464

The Mouse Monoclonal anti-IL-6 Receptor antibody is suitable to detect IL-6 Receptor in samples from Human. It has been validated for WB and ELISA.

Quick Overview for IL-6 Receptor antibody (AA 21-120) (ABIN561464)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2G6

Product Details anti-IL-6 Receptor Antibody

Binding Specificity: AA 21-120

Purpose: Mouse monoclonal antibody raised against a partial recombinant IL6R.

Sequence: APRRCPAQEV ARGVLTSLPG DSVTLTCPGV EPEDNATVHW VLRKPAAGSH PSRWAGMGRR LLLRSVQLHD SGNYSCYRAG RPAGTVHLLV DVPPEEPQLS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IL6R (NP_000556, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R

Background: Full Gene Name: interleukin 6 receptor
Synonyms: CD126,IL-6R-1,IL-6R-alpha,IL6RA,MGC104991

Gene ID: 3570

NCBI Accession: NM_000565

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints