Browse our IL11RA Proteins (IL11RA)

Full name:
Interleukin 11 Receptor, alpha Proteins (IL11RA)
On are 17 Interleukin 11 Receptor, alpha (IL11RA) Proteins from 6 different suppliers available. Additionally we are shipping IL11RA Antibodies (64) and IL11RA Kits (13) and many more products for this protein. A total of 103 IL11RA products are currently listed.
AI314697, CRSDA, fi26e06, GP130, Il-11ra, Il11ra, Il11ra2, NR1, wu:fi26e06
list all proteins Gene Name GeneID UniProt
IL11RA 3590 Q14626
IL11RA 16157 Q64385
IL11RA 245983 Q99MF4

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IL11RA Proteins (IL11RA) by Origin

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Human Interleukin 11 Receptor, alpha (IL11RA) interaction partners

  1. Report IL11RA and MELK (show MELK Proteins) amplification in gastric cancer cell lines and primary gastric adenocarcinomas.

  2. Data suggest domains D1-D3, which contain cytokine binding module, determine which cytokine can activate interleukin-6 (show IL6 Proteins) or interleukin-11 (show IL11 Proteins) alpha-receptor subunits; stalk, transmembrane, or intracellular regions do not participate in ligand selectivity.

  3. Proteolysis of the IL-11R represents a molecular switch that controls the IL-11 (show IL11 Proteins) trans-signaling pathway which is the target in intestinal tumorigenesis, lung carcinomas, and asthma.

  4. Constructed a designer cytokine Hyper IL-11 (show IL11 PLURAL_@42467@) (H11), which is exclusively composed of naturally existing components. It contains the full length sIL (show PMEL PLURAL_@42467@)-11Ralpha connected with the mature IL-11 (show IL11 PLURAL_@42467@) protein, and acts as an agonist on cells expressing the gp130 (show IL6ST PLURAL_@42467@) molec

  5. IL11RA promoter polymorphism--rs1061758--may be associated with the risk of papillary thyroid cancer in the Korean population.

  6. IL11 (show IL11 Proteins) as well as IL11RA are likely to play a role in the progression of endometrial carcinoma.

  7. the interleukin-11 receptor alpha-chain has evidence of antiapoptotic effects in human colonic epithelial cells

  8. interleukin-11 receptor is expressed in CD38-positive cells from patients with multiple myeloma

  9. High expression of interleukin-11 receptor alpha is associated with Hodgkin's lymphoma

  10. High interleukin 11 receptor is associated with breast cancer

Mouse (Murine) Interleukin 11 Receptor, alpha (IL11RA) interaction partners

  1. Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.

  2. In spite of clear changes in the temporal expression of both IL-11 (show IL11 Proteins) and its receptor, no significant differences in motor function are found after spinal cord injury.

  3. Signaling through the IL-35 receptor required the transcription factors STAT1 (show STAT1 Proteins) and STAT4 (show STAT4 Proteins).

  4. Demyelination and oligodendrocyte death are exacerbated in IL-11 receptor alpha-deficient mice, suggesting avenues to enhance oligodendrocyte viability and restrict central nervous system inflammation in multiple sclerosis.

  5. This study underlines the importance of gp130 (show LRPPRC PLURAL_@42467@) cytokines in proliferation and establishes its role in auto-paracrine pituitary growth regulation.

  6. IL-13 (show IL13 PLURAL_@42467@)-induced lung inflammation, remodeling, respiratory failure and death are all diminished in mice deficient in the IL-11 receptor alpha-gp130 (show LRPPRC PLURAL_@42467@) complex.

  7. IL-11 (show IL11 Proteins) signaling is clearly required for normal bone turnover and normal trabecular bone mass, yet not for the effects of estradiol or estrogen deficiency on the skeleton.

  8. These results provide, at least in part, an explanation for the defective small decidua of mice lacking the Il11ra gene, and reveal for the first time that cyclin D3 (show CCND3 Proteins), CDKN1A (p21 (show CDKN1A Proteins)), and BIRC5 (Survivin (show BIRC5 Proteins)) are targets of IL11 (show IL11 Proteins) in the decidua.

IL11RA Protein Profile

Protein Summary

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with IL11RA

  • interleukin 11 receptor, alpha (il11ra)
  • Interleukin-11 receptor subunit alpha-like (LOC556326)
  • interleukin 11 receptor, alpha (IL11RA)
  • interleukin 11 receptor, alpha chain 1 (Il11ra1)
  • AI314697 protein
  • CRSDA protein
  • fi26e06 protein
  • GP130 protein
  • Il-11ra protein
  • Il11ra protein
  • Il11ra2 protein
  • NR1 protein
  • wu:fi26e06 protein

Protein level used designations for IL11RA

interleukin 11 receptor alpha chain , interleukin-11 receptor subunit alpha , interleukin 11 receptor, alpha , IL-11 receptor subunit alpha , IL-11R subunit alpha , IL-11R-alpha , IL-11RA , Interleukin-11 receptor alpha chain , interleukin-11 receptor alpha chain , IL-11 receptor subunit alpha-1 , IL-11R subunit alpha-1 , IL-11R-alpha-1 , IL-11RA1 , Il-11ra-alpha , NR-1 , enhancer trap locus homolog 2 , etl-2 , interleukin 11 receptor, alpha chain 2 , interleukin-11 receptor subunit alpha-1 , locus 2 , novel cytokine receptor 1

334010 Danio rerio
556326 Danio rerio
100101801 Xenopus (Silurana) tropicalis
100190822 Pongo abelii
3590 Homo sapiens
481588 Canis lupus familiaris
508932 Bos taurus
693251 Gallus gallus
16157 Mus musculus
245983 Rattus norvegicus
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