IL11RA Protein (AA 24-370) (Fc Tag)
Quick Overview for IL11RA Protein (AA 24-370) (Fc Tag) (ABIN6992343)
Target
See all IL11RA ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Protein Characteristics
- AA 24-370
-
Purification tag / Conjugate
- This IL11RA protein is labelled with Fc Tag.
-
Purpose
- Human IL-11 R alpha Protein, Fc Tag (MALS verified)
-
Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- PBS, pH 7.4
-
Storage
- -20 °C
-
-
- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
-
Alternative Name
- IL-11 R alpha
-
Background
- Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
-
Molecular Weight
- 64.3 kDa
-
NCBI Accession
- NP_001136256
-
Pathways
- JAK-STAT Signaling, Growth Factor Binding
Target
-