Browse our anti-IL12 (IL12) Antibodies

Full name:
anti-Interleukin 12 Antibodies (IL12)
On www.antibodies-online.com are 236 Interleukin 12 (IL12) Antibodies from 23 different suppliers available. Additionally we are shipping IL12 Kits (184) and IL12 Proteins (64) and many more products for this protein. A total of 502 IL12 products are currently listed.
Synonyms:
CLMF, CLMF2, IL-12 p40, Il-12a, IL-12B, IL-12p35, IL-12p40, Il12, IL12B, il12p40.b, Ll12a, LOC100217488, NKSF, NKSF2, p35, zgc:152789
list all antibodies Gene Name GeneID UniProt
IL12 16159 P43431
IL12 64546  
IL12 3593 P29460

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Most Popular Reactivities for anti-IL12 (IL12) Antibodies

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anti-Mouse (Murine) IL12 Antibodies:

anti-Rat (Rattus) IL12 Antibodies:

anti-Human IL12 Antibodies:

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Top referenced anti-IL12 Antibodies

  1. Human Monoclonal IL12 Primary Antibody for FACS - ABIN2665815 : Belladonna, Renauld, Bianchi, Vacca, Fallarino, Orabona, Fioretti, Grohmann, Puccetti: IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 8 references for 2665815

  2. Mouse (Murine) Monoclonal IL12 Primary Antibody for Func, FACS - ABIN2665104 : Quesniaux: Interleukins 9, 10, 11 and 12 and kit ligand: a brief overview. in Research in immunology 1992 (PubMed)
    Show all 5 references for 2665104

  3. Mouse (Murine) Monoclonal IL12 Primary Antibody for IP, Neut - ABIN1177291 : DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. in The Journal of experimental medicine 1992 (PubMed)
    Show all 4 references for 1177291

  4. Human Monoclonal IL12 Primary Antibody for Neut, ELISA - ABIN1177266 : DAndrea, Aste-Amezaga, Valiante, Ma, Kubin, Trinchieri: Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. in The Journal of experimental medicine 1993 (PubMed)
    Show all 3 references for 1177266

  5. Mouse (Murine) Polyclonal IL12 Primary Antibody for ELISA, IHC - ABIN269610 : Zhang, Cao, Bai, Carr, Ella-Menye, Irvin, Ratner, Jiang: Zwitterionic hydrogels implanted in mice resist the foreign-body reaction. in Nature biotechnology 2013 (PubMed)
    Show all 2 references for 269610

  6. Human Polyclonal IL12 Primary Antibody for IF (p), IHC (p) - ABIN734453 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)

  7. Human Polyclonal IL12 Primary Antibody for FACS, IHC (p) - ABIN652878 : Sivakumar, Foster, Clegg: Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. in Immunology 2004 (PubMed)

  8. Human Polyclonal IL12 Primary Antibody for IF (p) - ABIN902152 : Friedemann, Kalbitzer, Franz, Moeller, Schnabelrauch, Simon, Pompe, Franke: Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks. in Advanced healthcare materials 2017 (PubMed)

  9. Human Monoclonal IL12 Primary Antibody for FACS - ABIN1383951 : Morandi, Levreri, Bocca, Galleni, Raffaghello, Ferrone, Prigione, Pistoia: Human neuroblastoma cells trigger an immunosuppressive program in monocytes by stimulating soluble HLA-G release. in Cancer research 2007 (PubMed)

More Antibodies against IL12 Interaction Partners

Mouse (Murine) Interleukin 12 (IL12) interaction partners

  1. findings show that IL-12 and other proinflammatory cytokines transduce signals through the TCR signalosome in a manner that requires Fyn activity and self-peptide-MHC (self-pMHC) interactions.

  2. this study shows that a systemic IL-12 (show IL12A Antibodies) primes intestinal cells that became more prone to develop inflammatory responses, which is long-lasting because intestinal cells maintain their inflammatory potential and their ability to aggravate colitis

  3. These results suggest a correlation between CRMP2 (show DPYSL2 Antibodies) phosphorylation and AD pathophysiology, and indicate the effectiveness of pioglitazone treatment at the pre-Abeta (show APP Antibodies) accumulation stage in AD model mice.

  4. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.

  5. Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.

  6. Deficiency of IL-12p35 limited AMI (show CFD Antibodies)-induced cardiac injury by promoting pro-angiogenesis and anti-inflammatory functions of monocytes

  7. IL-12 (show IL12A Antibodies) immunomodulation delays the onset of lethal peritoneal disease of ovarian cancer.

  8. There is a common program of effector T cell differentiation that is regulated by IL-2 and IL-12 signaling and the combined activities of the transcriptional regulators Blimp-1 and T-bet.

  9. Irradiation-induced IL-6 (show IL6 Antibodies) can decrease IL-12 (show IL12A Antibodies) production through the inhibition of C-Rel (show NFkBP65 Antibodies) phosphorylation by the IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies) signaling pathway.

  10. The IL-12 (show IL12A Antibodies) response by dendritic cells against S. aureus is highly growth phase dependent.

Human Interleukin 12 (IL12) interaction partners

  1. NOD2 (show NOD2 Antibodies) rs3135500 and IL12B (show IL12B Antibodies) rs1368439 SNPs were not genetic risk factors for colorectal cancer in the studied Iranian population.

  2. assembly-induced folding is key in IL-12 (show IL12A Antibodies) family biogenesis and secretion; the identification of essential disulfide bonds that underlie this process lays the basis for a simplified yet functional IL-12 (show IL12A Antibodies) cytokine

  3. IL-12B (show IL12B Antibodies) gene polymorphisms were not related with rheumatoid arthritis (RA). However, rs6887695 was associated with RA in Asian patients

  4. this study shows that that IL-12 (show IL12A Antibodies) and IL-4 (show IL4 Antibodies) govern group 2 innate lymphoid cells functional identity and that their imbalance results in the perpetuation of type 1 or type 2 inflammation

  5. The data suggested the association of IL12B (show IL12B Antibodies) with the psoriasis, however no evidence was observed for the epistatic effect of IL12B (show IL12B Antibodies) with HLA-Cw6 among the psoriasis patients in India.

  6. In summary, this meta-analysis finds that IL6 (show IL6 Antibodies) rs1800795 and IL18 (show IL18 Antibodies) rs1946518 polymorphisms decrease the risk of BD. However, IL12B (show IL12B Antibodies) rs3212227 increases BD susceptibility. Further large-scale investigation of this association is necessary.

  7. Suggest Il12B (show IL12B Antibodies) SNPs as genetic marker of disease severity in Takayasu arteritis severity.

  8. The results of this study suggested that rs6887695 SNP in IL12B (show IL12B Antibodies) gene increase susceptibility to relapsing-remitting multiple sclerosis.

  9. The results of this case-control study suggest that IL-12A (show IL12A Antibodies), IL-12B (show IL12B Antibodies), IL12RB1 (show IL12RB1 Antibodies), IL12RB2 (show IL12RB2 Antibodies) and IL23R (show IL23R Antibodies) make no genetic contribution to the susceptibility of Takayasu arteritis in Chinese populations

  10. these meta-analyses demonstrated that IL-12B (show IL12B Antibodies) rs3212227 and rs6887695 polymorphisms do not confer susceptibility to rheumatoid arthritis [data synthesis]

Pig (Porcine) Interleukin 12 (IL12) interaction partners

  1. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (show TNF Antibodies), IL-6 (show IL6 Antibodies), IL-12p40, IL-1beta (show IL1B Antibodies), and resulted in increased expression of the apoptosis initiator caspase-8 (show CASP8 Antibodies) and bcl2L1 (show BCL2L1 Antibodies).

IL12 Antigen Profile

Antigen Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Alternative names and synonyms associated with IL12

  • interleukin 12Ba (il12ba) antibody
  • interleukin 12B (LOC100217488) antibody
  • interleukin 12 p40 subunit (IL-12) antibody
  • interleukin 12a (Il12a) antibody
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) antibody
  • interleukin 12B (Il12b) antibody
  • interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (IL12B) antibody
  • CLMF antibody
  • CLMF2 antibody
  • IL-12 p40 antibody
  • Il-12a antibody
  • IL-12B antibody
  • IL-12p35 antibody
  • IL-12p40 antibody
  • Il12 antibody
  • IL12B antibody
  • il12p40.b antibody
  • Ll12a antibody
  • LOC100217488 antibody
  • NKSF antibody
  • NKSF2 antibody
  • p35 antibody
  • zgc:152789 antibody

Protein level used designations for anti-Interleukin 12 (IL12) Antibodies

il-12p40.a , interleukin 12 p40.b , interleukin 12B , interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) , interleukin 12Ba (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) , interleukin-12 p40 subunit , CLMF p40 , Cytotoxic lymphocyte maturation factor 40 kDa subunit , IL-12 subunit p40 , Interleukin-12 subunit beta , CLMF p35 , IL-12 subunit p35 , cytotoxic lymphocyte maturation factor 35 kDa subunit , interleukin 12a p35 subunit , interleukin-12 subunit alpha , IL-12A , interleukin 12 , interleukin-12 p40 , interleukin-12 subunit beta , IL12, subunit p40 , NK cell stimulatory factor chain 2 , cytotoxic lymphocyte maturation factor 40 kDa subunit , interleukin 12, p40 , interleukin-12 beta chain , natural killer cell stimulatory factor, 40 kD subunit , IL-12B , IL-12 p40 subunit , interleukin-12p40

GENE ID SPECIES
445373 Danio rerio
100217488 Taeniopygia guttata
100860845 Capra hircus
16159 Mus musculus
493741 Felis catus
64546 Rattus norvegicus
3593 Homo sapiens
397076 Sus scrofa
403976 Canis lupus familiaris
404671 Gallus gallus
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