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Human IL15 ELISA Kit for Sandwich ELISA - ABIN625012
Shoman, Nabil, Tabl, Ghanem, Kafrawy: Assessment of immunological changes in Epstein-Barr virus co-infection in Egyptian chronic HCV patients. in Memórias do Instituto Oswaldo Cruz 2014
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Rat (Rattus) IL15 ELISA Kit for Sandwich ELISA - ABIN416368
Molanouri Shamsi, Hassan, Gharakhanlou, Quinn, Azadmanesh, Baghersad, Isanejad, Mahdavi: Expression of interleukin-15 and inflammatory cytokines in skeletal muscles of STZ-induced diabetic rats: effect of resistance exercise training. in Endocrine 2014
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Rat (Rattus) IL15 ELISA Kit for Sandwich ELISA - ABIN365261
Zanchi, Lira, de Siqueira Filho, Rosa, de Oliveira Carvalho, Seelaender, Santos, Lancha: Chronic low frequency/low volume resistance training reduces pro-inflammatory cytokine protein levels and TLR4 mRNA in rat skeletal muscle. in European journal of applied physiology 2010
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Human IL15 ELISA Kit for Sandwich ELISA - ABIN414877
Shi, Liu, Zhang, Guo, Song, Song, Liu: miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice. in Medical science monitor : international medical journal of experimental and clinical research 2015
Mouse (Murine) IL15 ELISA Kit for Sandwich ELISA - ABIN365238
Yin, Xu, Sun, Wei, Tian: Interleukin-15 suppresses hepatitis B virus replication via IFN-? production in a C57BL/6 mouse model. in Liver international : official journal of the International Association for the Study of the Liver 2012
Human IL15 ELISA Kit for Sandwich ELISA - ABIN2684586
Conti, Frappier, Dharancy, Chereau, Houssin, Weill, Calmus: Interleukin-15 production during liver allograft rejection in humans. in Transplantation 2003
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Mouse (Murine) IL15 ELISA Kit for Sandwich ELISA - ABIN625405
Collignon, Perles-Barbacaru, Robert, Silvy, Martinez, Crenon, Germain, Garcia, Viola, Lombardo, Mas, Béraud: A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination. in Oncotarget 2015
T cells in chimpanzees infected with human immunodeficiency virus express surface interleukin-15.
CD3 (show CD3 ELISA Kits)(-) CD8 (show CD8A ELISA Kits)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma (show IFNG ELISA Kits), and that IL-15 elicits IFN-gamma (show IFNG ELISA Kits) production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 (show CD8A ELISA Kits) antigen, IFN-gamma (show IFNG ELISA Kits)]
findings extend understanding of the differential modes of action between IL-2 (show IL2 ELISA Kits) and IL-15, and highlight how, although sharing the CD122 (show IL2RB ELISA Kits)/CD132 (show IL2RG ELISA Kits) receptor, they elicit such different immune actions
IL-15 induced by inflammatory signals in response to lymphodepletion drives lymphocyte responses, as memory CD8 (show CD8A ELISA Kits) T cells proliferated in an IL-15-dependent manner.
these findings unveil a role for IL-15 as a critical mediator in defense against systemic candidiasis and hold promise for the design of IL-15-based antifungal immunotherapies.
developmental arrest of Natural killer cells results from a lack of IL-15 availability in the microenvironment.
IL-15 impacts butyrate-producing bacteria and lowers butyrate levels in the absence of overt pathology, which represent events that precede and promote intestinal inflammatory diseases.
endogenous IL-15 does not directly augment the pathogenesis of sepsis but enables the development of septic shock by maintaining NK cell numbers and integrity.
this study shows that IL-15-mediated control of the precursor population affects the development of virus-specific CD8 (show CD8A ELISA Kits)+ T-cell memory
this study shows that unleashed trans-presentation of IL-15 on MyD88 (show MYD88 ELISA Kits)-deficient fibroblastic reticular cells during viral infection fosters the activation of cytotoxic and non-cytotoxic group 1 innate lymphoid cells and accelerates clearance of the virus
this study shows that synergistic enhancement of adaptive immunity by the combination of epigallo catechin gallate and vitamin A or E is dependent on both IL-15 and its receptor
Under steady-state conditions, KLF2 (show KLF2 ELISA Kits)-deficient NK cells alter their expression of homeostatic homing receptors and subsequently undergo apoptosis due to IL-15 starvation.
IL-15 drives bystander activation of CD8 (show CD8A ELISA Kits)+ T cells, which predicts disease progression in untreated HIV-1-infected patients and suggests that elevated IL-15 may also drive CD8 (show CD8A ELISA Kits)+ T cell expansion that is linked to increased morbidity and mortality in treated patients
Sustained virologic response was significantly associated with IL15 rs10833 in chronic hepatitis C patients, treated with pegylated interferon-alpha (show IFNA ELISA Kits) and ribavirin.
IL-15 mRNA and protein levels significantly increased in rhHBcAg stimulation group compared with non-stimulated group.
this work provides evidence that the sushi-IL-15Ralpha/IL-15 fusion protein RLI (show ABCE1 ELISA Kits) enhances antitumor activity of anti-PD-1 (show PDCD1 ELISA Kits) treatment and is a promising approach to stimulate host immunity
These results reveal a novel role of IL-7 (show IL7 ELISA Kits) and IL-15 in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.
This analysis revealed highly connected functional interaction networks with two candidate genes, IL15 and SEC14L5 highly enriched in networks. Overall, from these results, we concluded that these genes can be recommended as some of the potential targets for Post-Traumatic Stress Disorder.
These data support a potential role for IL-15 in the pathogenesis of HIV-associated immune activation.
Cutaneous T-cell lymphoma (CTCL (show TSPYL2 ELISA Kits)) pathogenesis remains unknown, and there are no curative therapies. Our findings not only demonstrate a critical role for IL15-mediated inflammation in cutaneous T-cell lymphomagenesis, but also uncover a new oncogenic regulatory loop in CTCL (show TSPYL2 ELISA Kits) involving IL15, HDAC1 (show HDAC1 ELISA Kits), HDAC6 (show HDAC6 ELISA Kits), and miR (show MLXIP ELISA Kits)-21 that shows differential sensitivity to isotype-specific HDAC (show HDAC3 ELISA Kits) inhibitors
we provide the first direct evidence that IL-15 is expressed both at the mRNA and protein level in human salivary gland epithelial cells and it is clear that salivary glands from primary Sjogren's syndrome patients showed an intensified epithelial expression of IL-15
Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.
results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC (show FYN ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits) pathways
IFN-gamma (show IFNG ELISA Kits) targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response
When induced by IFN-gamma (show IFNG ELISA Kits) or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response.
Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2 (show BCL2 ELISA Kits).
IL 15 generates a dramatic expansion of short-lived memory CD8 (show CD8A ELISA Kits) T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4 (show CD4 ELISA Kits)(+) and CD8 (show CD8A ELISA Kits)(+) T cells.
These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 (show CD4 ELISA Kits) + T cell compartment.
IL-15 secretion significantly correlates with the up-regulated expression of CD4 (show CD4 ELISA Kits) on memory CD4 (show CD4 ELISA Kits) T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.