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Human IL15 ELISA Kit for Sandwich ELISA - ABIN411313
Conti, Frappier, Dharancy, Chereau, Houssin, Weill, Calmus: Interleukin-15 production during liver allograft rejection in humans. in Transplantation 2003
Show all 2 references for ABIN411313
Rat (Rattus) IL15 ELISA Kit for Sandwich ELISA - ABIN416368
Molanouri Shamsi, Hassan, Gharakhanlou, Quinn, Azadmanesh, Baghersad, Isanejad, Mahdavi: Expression of interleukin-15 and inflammatory cytokines in skeletal muscles of STZ-induced diabetic rats: effect of resistance exercise training. in Endocrine 2014
Show all 2 references for ABIN416368
Mouse (Murine) IL15 ELISA Kit for Sandwich ELISA - ABIN365238
Yin, Xu, Sun, Wei, Tian: Interleukin-15 suppresses hepatitis B virus replication via IFN-? production in a C57BL/6 mouse model. in Liver international : official journal of the International Association for the Study of the Liver 2012
T cells in chimpanzees infected with human immunodeficiency virus express surface interleukin-15.
CD3 (show CD3 ELISA Kits)(-) CD8 (show CD8A ELISA Kits)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma (show IFNG ELISA Kits), and that IL-15 elicits IFN-gamma (show IFNG ELISA Kits) production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 (show CD8A ELISA Kits) antigen, IFN-gamma (show IFNG ELISA Kits)]
Impaired delivery of IL-15 to CD4 (show CD4 ELISA Kits)+ T cells in the colon downmodulates Foxp3 (show FOXP3 ELISA Kits) expression and enhances RORgammat expression. CD4 (show CD4 ELISA Kits)+ T cells deprived of IL-15 trigger IBD characterized by production of pro-inflammatory cytokines and accumulation of Th1 (show HAND1 ELISA Kits)/Th17 cells.
Most (86%) IL15 in serum resides in the free state, with a minor proportion (14%) residing in complex with IL15Ralpha. Results suggest that IL15 is released as a free molecule by an unknown mechanism rather than via cleavage of membrane-bound IL15/IL15Ralpha.
IL-15 may influence mononuclear phagocytes subsets in the gut (show GUSB ELISA Kits) in a novel way that alters the frequency of lamina propria Th17 cells.
Downregulation of STAT3 (show STAT3 ELISA Kits) phosphorylation enhances tumoricidal effect of IL-15-activated dendritic cell against doxorubicin-resistant lymphoma and leukemia via TNF-alpha (show TNF ELISA Kits).
Exercise-stimulated interleukin-15 is controlled by AMPK (show PRKAA1 ELISA Kits) and regulates skin metabolism and aging.
IL-15 specifically down-regulates RARB (show RARB ELISA Kits) expression, and RARB (show RARB ELISA Kits) may play a protective role in lung injury caused by smoking or viral infections.
Hair follicle expression of IL-15 was required for CD8+ skin-resident memory T (TRM) cells to exert tropism for the epidermis.
High levels of IL-15 can promote tumor destruction and reduce metastasis in breast cancer via effects on NK1.1 positive cells.
The role of the IL-15 receptor alpha (show IL15RA ELISA Kits) in metabolism and obesity is reported.
We demonstrated that IL-15 has a role in mammary cancer immunosurveillance and that IL-15-regulated NK and CD8 (show CD8A ELISA Kits)+ memory cells play a role in long-lasting immunoprevention
Protein, mRNA, and serum expression levels of MMP-7 (show MMP7 ELISA Kits) and IL-15 in patients with osteoarthritis were all significantly increased in osteoarthritis patients compared with the control group.
Common gamma-chain (show IL2RG ELISA Kits) cytokines IL-2 (show IL2 ELISA Kits), IL-7 (show IL7 ELISA Kits), and IL-15 prevent differentiation of naive T cells in vitro and limit activation of primed T cells in the absence of antigenic stimulus, which can contribute to the formation of cytokine imbalance.
Studeis indicate that expression of interleukin-15 (IL-15) in tissues promotes T helper 1 cell-mediated immunity.
These findings demonstrate a novel mechanism to attenuate IL-15-dependent NK cell proliferation and suggest that inhibitory NK cell receptors contribute to NK cell homeostasis.
IL15 was expressed primarily in the suprabulb of the hair follicle.
IL-15-derived dendritic cells elicited greater antigen-specific, primary and secondary CD8 (show CD8A ELISA Kits) and CD4 (show CD4 ELISA Kits) T-cell responses than did IL-4 (show IL4 ELISA Kits)-derived ones
Our study provides a better understanding of IL-15 signaling in renal cell carcinoma tumor progression
Our data suggest that serum IL-15 at diagnosis is a novel, powerful predictor of prognosis for extranodal NK/T cell lymphoma
Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.
results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC (show FYN ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits) pathways
IFN-gamma (show IFNG ELISA Kits) targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response
When induced by IFN-gamma (show IFNG ELISA Kits) or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response.
Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2 (show BCL2 ELISA Kits).
IL 15 generates a dramatic expansion of short-lived memory CD8 (show CD8A ELISA Kits) T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4 (show CD4 ELISA Kits)(+) and CD8 (show CD8A ELISA Kits)(+) T cells.
These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 (show CD4 ELISA Kits) + T cell compartment.
IL-15 secretion significantly correlates with the up-regulated expression of CD4 (show CD4 ELISA Kits) on memory CD4 (show CD4 ELISA Kits) T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.