Browse our IL5RA Proteins (IL5RA)

Full name:
Interleukin 5 Receptor, alpha Proteins (IL5RA)
On are 18 Interleukin 5 Receptor, alpha (IL5RA) Proteins from 8 different suppliers available. Additionally we are shipping IL5RA Antibodies (108) and IL5RA Kits (15) and many more products for this protein. A total of 150 IL5RA products are currently listed.
CD125, CDw125, gpIL-5ra, HSIL5R3, Il5r, IL5RA, MGC86517
list all proteins Gene Name GeneID UniProt
IL5RA 3568 Q01344
Rat IL5RA IL5RA 114103  
IL5RA 16192 P21183

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IL5RA Proteins (IL5RA) by Origin

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Top referenced IL5RA Proteins

  1. Human IL5RA Protein expressed in HEK-293 Cells - ABIN2181392 : Tavernier, Devos, Cornelis, Tuypens, Van der Heyden, Fiers, Plaetinck: A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. in Cell 1991 (PubMed)
    Show all 3 references for 2181392

  2. Human IL5RA Protein expressed in Human Cells - ABIN2002761 : Laundy, Bidwell: Human cytokine gene nucleotide sequence alignments: interleukin 4 receptor alpha chain (IL4RA), IL5RA, IL8, IL8RB and IL13. in European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003 (PubMed)
    Show all 2 references for 2002761

  3. Mouse (Murine) IL5RA Protein expressed in Baculovirus infected Insect Cells - ABIN2008711 : Cen, Gorska, Stafford, Sur, Alam: Identification of UNC119 as a novel activator of SRC-type tyrosine kinases. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 2008711

More Proteins for IL5RA Interaction Partners

Human Interleukin 5 Receptor, alpha (IL5RA) interaction partners

  1. Interleukin-5Ralpha-targeted treatments offer promises to patients with eosinophilic respiratory disorders; review

  2. This is the first study to show significant associations between IL5RA SNP rs17881144, the ATTAGA haplotype, the GTAGCA haplotype, and the GCTGCA haplotype and eczema.

  3. This is the first study to show significant associations between IL5RA SNP rs6771148, the ACTAGA haplotype, and the GTAGCA haplotype and the risk of rhinoconjunctivitis.

  4. The MDR analysis showed a potential interaction of C1GALT1-330G/T (rs1008898) and IL5RA31+197A/G (rs340833) on the susceptibility of IgAN (P<0.001). Gene-gene interaction may have some influence on the susceptibility to IgA nephropathy.

  5. These findings suggest that a functional polymorphism in IL5RA may contribute to eosinophil and mast cell activation along with specific IgE responses to staphylococcal enterotoxin A in aspirin-exacerbated respiratory disease patients.

  6. The study reports the crystal structure of dimeric IL-5 (show IL5 Proteins) in complex with the IL5RA extracellular domains.

  7. REVIEW: Interleukin-5 (show IL5 Proteins) and IL-5 (show IL5 Proteins) receptor in health and disease

  8. we determined the structure of IL-5 (show IL5 Proteins) bound to the extracellular domain of IL-5Ralpha.

  9. Polymorphisms in IL5RA, LPL (show LCP1 Proteins), ITGA2 (show ITGA2 Proteins) and NOS3 (show NANOS3 Proteins) genes were independently associated with ischemic stroke in Chinese diabetic population.

  10. findings are consistent with an airway tissue-selective expression of the IL-5 (show IL5 Proteins) receptor that mediates IL-5 (show IL5 Proteins)-induced airway hyperresponsiveness independent of eosinophils

Mouse (Murine) Interleukin 5 Receptor, alpha (IL5RA) interaction partners

  1. SLy2 (show SAMSN1 Proteins) controls the antibody response to pneumococcal vaccine through an IL-5Ralpha-dependent mechanism in B-1 cells.

  2. Interleukin-5 receptor alpha chain expression and splicing during brain development in mice.

  3. IL-5 (show IL5 Proteins) is not necessary for differential splicing to occur in vivo, as all three forms of the IL-5R alpha are detected in both strains of IL-5 (show IL5 Proteins) gene (show GPD1 Proteins)-deleted mice

  4. Octamer Transcription Factor 2 (show HNF1B Proteins) (Oct2 (show SLC22A2 Proteins)) augments the ability of activated B cells to differentiate to antibody-secreting plasma cells under T cell-dependent conditions through regulation of the gene encoding the interleukin 5 receptor alpha chain.

  5. We identified B-1 progenitors expressing low levels of IL-5 receptor alpha chain (IL-5Ralpha) and eosinophil progenitors expressing higher levels of IL-5Ralpha in the fetal liver

  6. The murine interleukin-5 receptor alpha chain pre-mRNA is alternatively spliced, resulting in soluble isoforms lacking the transmembrane coding region which do not complex with the IL-5R beta chain.

IL5RA Protein Profile

Protein Summary

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Alternative names and synonyms associated with IL5RA

  • interleukin 5 receptor, alpha (il5ra)
  • interleukin 5 receptor, alpha (IL5RA)
  • interleukin 5 receptor, alpha (Il5ra)
  • CD125 protein
  • CDw125 protein
  • gpIL-5ra protein
  • HSIL5R3 protein
  • Il5r protein
  • IL5RA protein
  • MGC86517 protein

Protein level used designations for IL5RA

interleukin 5 receptor, alpha , Interleukin-5 receptor subunit alpha , interleukin-5 receptor subunit alpha , interleukin 5 receptor alpha , interleukin-5 receptor, alpha , interleukin-5 receptor subunit alpha-like , CD125 antigen , IL-5 receptor subunit alpha , IL-5R subunit alpha , interleukin 5 receptor type 3 , interleukin-5 receptor alpha chain , IL-5 receptor alpha chain , IL-5R-alpha , IL-5RA

447644 Xenopus laevis
476553 Canis lupus familiaris
615848 Bos taurus
704649 Macaca mulatta
737582 Pan troglodytes
771801 Gallus gallus
100137085 Sus scrofa
100144707 Xenopus (Silurana) tropicalis
100379257 Cavia porcellus
100414222 Callithrix jacchus
100450437 Pongo abelii
100584044 Nomascus leucogenys
3568 Homo sapiens
114103 Rattus norvegicus
16192 Mus musculus
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