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IL5RA Protein (AA 21-335) (His-Avi Tag)

IL5RA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275034
  • Target See all IL5RA Proteins
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-335
    Origin
    • 13
    • 8
    Human
    Source
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL5RA protein is labelled with His-Avi Tag.
    Purpose
    Human IL-5 R alpha/CD125 Protein
    Sequence
    Asp21-Glu335
    Characteristics
    Recombinant Human IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp21-Glu335.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 4.9nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL5RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
    Alternative Name
    IL-5 R alpha (IL5RA Products)
    Synonyms
    MGC86517 Protein, IL5RA Protein, il5r Protein, cdw125 Protein, hsil5r3 Protein, gpIL-5ra Protein, CD125 Protein, CDw125 Protein, HSIL5R3 Protein, IL5R Protein, Il5r Protein, interleukin 5 receptor subunit alpha L homeolog Protein, interleukin 5 receptor subunit alpha Protein, interleukin 5 receptor, alpha Protein, il5ra.L Protein, IL5RA Protein, il5ra Protein, Il5ra Protein
    Background
    Interleukin-5 Receptor alpha (IL-5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
    Molecular Weight
    38.7 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result.
    Pathways
    JAK-STAT Signaling
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