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Browse our anti-IL6ST (IL6ST) Antibodies

Full name:
anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) Antibodies (IL6ST)
On www.antibodies-online.com are 149 Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) Antibodies from 20 different suppliers available. Additionally we are shipping IL6ST Proteins (22) and IL6ST Kits (15) and many more products for this protein. A total of 202 IL6ST products are currently listed.
Synonyms:
5133400A03Rik, AA389424, Ac1055, BB405851, CD130, CDW130, D13Ertd699e, GP130, IL-6RB
list all antibodies Gene Name GeneID UniProt
IL6ST 16195 Q00560
IL6ST 25205  
IL6ST 3572 P40189

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Most Popular Reactivities for anti-IL6ST (IL6ST) Antibodies

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anti-Mouse (Murine) IL6ST Antibodies:

anti-Rat (Rattus) IL6ST Antibodies:

anti-Human IL6ST Antibodies:

All available anti-IL6ST Antibodies

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Top referenced anti-IL6ST Antibodies

  1. Human Monoclonal IL6ST Primary Antibody for Func, FACS - ABIN1105847 : Anhuf, Weissenbach, Schmitz, Sobota, Hermanns, Radtke, Linnemann, Behrmann, Heinrich, Schaper: Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 22 references for ABIN1105847

  2. Human Monoclonal IL6ST Primary Antibody for WB - ABIN393214 : Johnatty, Beesley, Chen, Macgregor, Duffy, Spurdle, deFazio, Gava, Webb, Rossing, Doherty, Goodman, Lurie, Thompson, Wilkens, Ness, Moysich, Chang-Claude, Wang-Gohrke, Cramer, Terry, Hankinson, Tworoger, Garcia-Closas, Yang, Lissowska, Chanock, Pharoah, S: Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". in PLoS genetics 2010 (PubMed)
    Show all 5 references for ABIN393214

  3. Human Monoclonal IL6ST Primary Antibody for ELISA, WB - ABIN393207 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393207

  4. Human Monoclonal IL6ST Primary Antibody for Func, FACS - ABIN1105845 : Auguste, Guillet, Fourcin, Olivier, Veziers, Pouplard-Barthelaix, Gascan: Signaling of type II oncostatin M receptor. in The Journal of biological chemistry 1997 (PubMed)
    Show all 5 references for ABIN1105845

  5. Human Monoclonal IL6ST Primary Antibody for EIA, FACS - ABIN1105843 : Matsuda, Hirano: Establishment of the ELISA for murine soluble gp130, a signal transducer for the IL-6 family cytokine, and its detection in the ascitic fluids of tumor-bearing mice. in Biochemical and biophysical research communications 1994 (PubMed)
    Show all 4 references for ABIN1105843

  6. Human Monoclonal IL6ST Primary Antibody for EIA, FACS - ABIN1105848 : Chevalier, Fourcin, Robledo, Wijdenes, Pouplard-Barthelaix, Gascan: Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN1105848

  7. Human Polyclonal IL6ST Primary Antibody for EIA, IHC (p) - ABIN951186 : Goette, Lev, Heller, Glembotsky, Chazarreta, Salim, Molinas, Marta: Abnormal regulation of soluble and anchored IL-6 receptor in monocytes from patients with essential thrombocythemia. in Experimental hematology 2010 (PubMed)
    Show all 3 references for ABIN951186

  8. Human Polyclonal IL6ST Primary Antibody for EIA - ABIN453269 : Lehmann, Schmitz, Weissenbach, Sobota, Hortner, Friederichs, Behrmann, Tsiaris, Sasaki, Schneider-Mergener, Yoshimura, Neel, Heinrich, Schaper: SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN453269

  9. Human Monoclonal IL6ST Primary Antibody for FACS - ABIN1105854 : Menetrier-Caux, Thomachot, Alberti, Montmain, Blay: IL-4 prevents the blockade of dendritic cell differentiation induced by tumor cells. in Cancer research 2001 (PubMed)
    Show all 2 references for ABIN1105854

  10. Human Monoclonal IL6ST Primary Antibody for FACS - ABIN1105851 : Kurth, Horsten, Pflanz, Timmermann, Küster, Dahmen, Tacken, Heinrich, Müller-Newen: Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)

More Antibodies against IL6ST Interaction Partners

Mouse (Murine) Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) interaction partners

  1. IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) signalling in the osteoclast is not essential for normal bone resorption in vivo, but maintains both trabecular and periosteal bone formation in male mice by promoting osteoblast activity through the stimulation of osteoclast-derived coupling factors and osteotransmitters

  2. gp130 (show LRPPRC Antibodies)-mediated adipose tissue lipolysis promotes hepatic steatosis and insulin (show INS Antibodies) resistance.

  3. differences exist in the expression of receptors utilized by the IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) family of cytokines in astrocytes and microglia, and (2) the findings provide a molecular basis for the differential response to oncostatin M (show OSM Antibodies) by astrocytes versus microglia

  4. Deregulation of gp130 (show LRPPRC Antibodies)/STAT3 (show STAT3 Antibodies) signalling augments the acute phase reponse and macrophage infiltration during atherosclerosis without impacting on the development of aortic plaques.

  5. Significant differential expression (both increases and decreases) of multiple IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) cytokines, such as LIF (show LIF Antibodies), oncostatin-M (show OSM Antibodies), and ciliary neurotrophic factor (show CNTF Antibodies), occurred after Muller cell ablation

  6. GP130 (show LRPPRC Antibodies) signaling collaborated with MYC (show MYC Antibodies) to induce MM and was responsible and sufficient for directing the plasma cell phenotype.

  7. gp130 (show LRPPRC Antibodies), a co-receptor for IL-6 (show IL6 Antibodies) cytokines, triggers activation of YAP (show YAP1 Antibodies) and Notch (show NOTCH1 Antibodies), transcriptional regulators that control tissue growth and regeneration, independently of the gp130 (show LRPPRC Antibodies) effector STAT3 (show STAT3 Antibodies)

  8. osteocytic gp130 (show LRPPRC Antibodies) signaling is required for normal trabecular bone mass and proper cortical bone composition.

  9. PGF2alpha inhibits adipocyte differentiation by means of an IL-11 (show IL11 Antibodies) mediated autocrine negative feedback loop, that acts via gp130 (show LRPPRC Antibodies) to block adipogenesis through the essential actions of the STAT1 (show STAT1 Antibodies) transcription factor.

  10. Osteocytic gp130 (show LRPPRC Antibodies) is required to maintain PTH1R (show PTH1R Antibodies) expression in the osteoblast lineage, and for the stimulation of osteoblast differentiation that occurs in response to PTH (show PTH Antibodies).

Human Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) interaction partners

  1. High serum GP130 levels were associated with Chronic Spontaneous Urticaria.

  2. PECs exhibited higher proliferation in response to IL-6 (show IL6 Antibodies)/sIL (show PMEL Antibodies)-6R co-treatment compared with TECs in HCC (show FAM126A Antibodies) via the up-regulation of gp130 /JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies).

  3. Mutations leading to constitutive active gp130/JAK1 (show JAK1 Antibodies)/STAT3 (show STAT3 Antibodies) pathway.

  4. In the present study, we analyze the role of a unique cysteine residue (Cys (show DNAJC5 Antibodies)-628) within this C-terminus, which is contained neither in the membrane-bound gp130 nor in the two other sgp130 forms.

  5. pulmonary exposure to MWCNT can manifest as a reduced epithelial barrier and activator of vascular gp130-associated transsignaling that may promote susceptibility to cardiovascular derangements

  6. Diabetic rats show an increase in the contractions of distal colon partly via the IL-6-IL-6 (show IL6 Antibodies) receptor pathway.

  7. Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6 (show IL6 Antibodies)/gp130/STAT3 (show STAT3 Antibodies) Pathway.

  8. Increased soluble gp130 in older patients may inhibit IL-6 (show IL6 Antibodies) trans-signaling, impair barrier function, and decrease S100A8 (show S100A8 Antibodies)/ S100A9 (show S100A9 Antibodies) production in elderly chronic rhinosinusitis patients with asthma and nasal polyps.

  9. Data (including data from molecular dynamics simulation studies) suggest that conformation of GP130 (domains 2 and 3) changes and fluctuates only modestly (inter-domain angles vary only 125-140 degrees).

  10. GP130 signaling collaborated with MYC (show MYC Antibodies) to induce MM and was responsible and sufficient for directing the plasma cell phenotype.

IL6ST Antigen Profile

Antigen Summary

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17.

Alternative names and synonyms associated with IL6ST

  • interleukin 6 signal transducer (Il6st) antibody
  • interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST) antibody
  • 5133400A03Rik antibody
  • AA389424 antibody
  • Ac1055 antibody
  • BB405851 antibody
  • CD130 antibody
  • CDW130 antibody
  • D13Ertd699e antibody
  • GP130 antibody
  • IL-6RB antibody

Protein level used designations for IL6ST

IL-6 receptor subunit beta , IL-6R subunit beta , IL-6R-beta , IL-6RB , interleukin-6 receptor subunit beta , interleukin-6 signal transducer , membrane glycoprotein 130 , oncostatin-M receptor subunit alpha , CD130 antigen , gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form , interleukin receptor beta chain , membrane glycoprotein gp130

GENE ID SPECIES
16195 Mus musculus
25205 Rattus norvegicus
3572 Homo sapiens
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