Browse our anti-LIF (LIF) Antibodies

Full name:
anti-Leukemia Inhibitory Factor Antibodies (LIF)
On www.antibodies-online.com are 152 Leukemia Inhibitory Factor (LIF) Antibodies from 30 different suppliers available. Additionally we are shipping LIF Proteins (88) and LIF Kits (80) and many more products for this protein. A total of 337 LIF products are currently listed.
Synonyms:
A230075M04Rik, AW061234, CDF, DIA, HILDA, LIF, MLPLI
list all antibodies Gene Name GeneID UniProt
LIF 16878 P09056
LIF 3976 P15018
LIF 60584  

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Most Popular Reactivities for anti-LIF (LIF) Antibodies

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anti-Mouse (Murine) LIF Antibodies:

anti-Human LIF Antibodies:

anti-Rat (Rattus) LIF Antibodies:

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Top referenced anti-LIF Antibodies

  1. Cow (Bovine) Polyclonal LIF Primary Antibody for WB - ABIN2785833 : Muntz, Malpass, McGonigle, Robertson, Weiden: Phase 2 study of intraperitoneal topotecan as consolidation chemotherapy in ovarian and primary peritoneal carcinoma. in Cancer 2008 (PubMed)
    Show all 2 references for 2785833

  2. Human Polyclonal LIF Primary Antibody for IF (p), IHC (p) - ABIN737046 : Liang, Zhou, Jiang, Zhang, Wang, Wang: Expression of LIF and LIFR in periodontal tissue during orthodontic tooth movement. in The Angle orthodontist 2011 (PubMed)

  3. Human Polyclonal LIF Primary Antibody for ELISA, ICC - ABIN4330945 : Gao, Carson: Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes. in American journal of physiology. Cell physiology 2016 (PubMed)

  4. Human Polyclonal LIF Primary Antibody for EIA, FACS - ABIN453168 : Novotný, Krízan, Síma, Síma, Uher, Zech, Hütelová, Baborová, Ulcová-Gallová, Subrt, Ulmanová, Houdek, Rokyta, Babuska, Králícková: Leukaemia inhibitory factor (LIF) gene mutations in women diagnosed with unexplained infertility and endometriosis have a negative impact on the IVF outcome. A pilot study. in Folia biologica 2009 (PubMed)

More Antibodies against LIF Interaction Partners

Mouse (Murine) Leukemia Inhibitory Factor (LIF) interaction partners

  1. LIF stimulates, in part, stem cell-derived cardiomyocyte regeneration by activating cardiac stem or precursor cells.

  2. Our data show that absence of SOCS2 (show SOCS2 Antibodies) turns cardiomyocytes unresponsive to LIF-induced [Ca(2 (show CA2 Antibodies)+)] raise, indicating that endogenous levels of SOCS2 (show SOCS2 Antibodies) are crucial for full activation of LIF signaling in the heart.

  3. OSM (show OSM Antibodies) (mOSM) signals mainly via an OSM (show OSM Antibodies) receptor (OSMR (show OSMR Antibodies))-gp130 (show LRPPRC Antibodies) heterodimer and binds with only very low affinity to mLIFR.

  4. These results establish that Bcl3 (show BCL3 Antibodies) positively regulates pluripotency genes and thus shed light on the mechanism of Bcl3 (show BCL3 Antibodies) as a downstream molecule of LIF/STAT3 (show STAT3 Antibodies) signaling in pluripotency maintenance.

  5. The role of LIF in acetylcholine synthesis via the STAT3 (show STAT3 Antibodies), PI3 (show PI3 Antibodies) kinases, or cAMP-protein kinase A pathways, are reported.

  6. Either LIF or EGF (show EGF Antibodies) is needed during development of pre-implantation embryo.

  7. Our data suggest that LIF plays an important role in placentation in vivo and the maintenance of healthy pregnancy.

  8. Despite common signal transduction mechanisms (JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies), MAPK (show MAPK1 Antibodies) and PI3K) LIF can have paradoxically opposite effects in different cell types including stimulating or inhibiting each of cell proliferation, differentiation and survival.

  9. Mechanistically, LIF activates STAT (show STAT1 Antibodies), which binds to a Stat (show STAT1 Antibodies) consensus sequence in the Six2 (show SIX2 Antibodies) proximal promoter and sustains SIX2 (show SIX2 Antibodies) levels.

  10. These findings suggest that maternal IL-6 (show IL6 Antibodies) interferes the maternal-fetal LIF signal relay by inducing SOCS3 (show SOCS3 Antibodies) in the placenta and leads to decreased neurogenesis.

Human Leukemia Inhibitory Factor (LIF) interaction partners

  1. Data suggest a 216-nucleotide proximal cis (show CISH Antibodies)-element in LIF mRNA exhibits mRNA destabilizing potential; on exposure to carcinogen PMA (phorbol-12-myristate-13-acetate), this cis (show CISH Antibodies)-element exhibits mRNA stabilizing activity. PMA induces nucleo-cytoplasmic translocation of both nucleolin (show NCL Antibodies) and PCBP1 (show PCBP1 Antibodies), 2 trans-acting factors that bind to and stabilize LIF mRNA. [LIF = leukemia inhibitory factor; PCBP1 (show PCBP1 Antibodies) = poly(rC) binding protein 1 (show PCBP1 Antibodies)]

  2. Leukemia inhibitory factor (LIF) - STAT3 (show STAT3 Antibodies) transcription factor (STAT3 (show STAT3 Antibodies)) signaling pathway is systemically dysregulated in in the endometrium of patients with recurrent/repeated implantation failure (RIFE).

  3. Endometrial expression of LIF and LIFR (show LIFR Antibodies) is significantly reduced in the epithelial cells of infertile women.

  4. LIF SNP T/G (rs929271) seems to be a susceptibility biomarker capable of predicting implantation efficiency and pregnancy outcomes.

  5. Overexpression of LIF promotes Epithelial-mesenchymal transition and results in cancer.

  6. This review discusses the role of LIF and the recent analysis of its action on the uterine LE in regulating endometrial receptivity and implantation.

  7. Women with dormant genital tuberculosis were found to have decreased endometrial LIF-STAT3 (show STAT3 Antibodies) signaling.

  8. Data show that leukemia inhibitory factor (LIF) signaling promote chemoresistance in cholangiocarcinoma by up-regulating myeloid cell factor-1 (Mcl-1 (show MCL1 Antibodies)) via phosphatidylinositol 3-kinase (PI3K (show PIK3CA Antibodies))/c-akt (show AKT1 Antibodies) protein (AKT (show AKT1 Antibodies))-dependent pathway.

  9. Despite common signal transduction mechanisms (JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies), MAPK (show MAPK1 Antibodies) and PI3K (show PIK3CA Antibodies)) LIF can have paradoxically opposite effects in different cell types including stimulating or inhibiting each of cell proliferation, differentiation and survival.

  10. Taken together, we firstly demonstrate that LIF enhances the adhesion of trophoblastic cells to endometrial cells by up-regulating expression of integrin heterodimer alphaVbeta3 and alphaVbeta5.

Pig (Porcine) Leukemia Inhibitory Factor (LIF) interaction partners

  1. Cell cycle synchronization of leukemia inhibitory factor (LIF)-dependent porcine-induced pluripotent stem cells and the generation of cloned embryos.

  2. Studied effect of recombinant porcine leukemia inhibitory factor on in vitro maturation of porcine oocytes; p-STAT3 (show STAT3 Antibodies) markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 Antibodies)-supplemented media.

  3. LIF and IL-6 (show IL6 Antibodies) are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.

  4. Reprogramming pig fetal fibroblasts reveals a functional LIF signaling pathway.

  5. favorable effect on litter size in pigs of the A allele for a SNP within the LIF gene

  6. LIF (Leukemia inhibitory factor) mRNA was elevated in stented segments of coronary arteries; vascular smooth muscle cell proliferation was inhibited by LIF treatment in an in-vitro model of atherosclerosis

  7. study found significant association of two diallelic polymorphisms in the porcine genes for leukaemia inhibitory factor (LIF) and retinol-binding protein 4 (RBP4 (show RBP4 Antibodies)) with number of piglets born alive (NBA) in two German pig lines

Cow (Bovine) Leukemia Inhibitory Factor (LIF) interaction partners

  1. Studied the effects of leukemia inhibitory factor (LIF) on bovine oocyte maturation and early embryo development in vitro.

  2. results suggest that leukemia inhibitory factor and macrophage-colony stimulating factor (show CSF2 Antibodies) are produced in the endometrium and may play different roles in early and mid-pregnancy

LIF Antigen Profile

Antigen Summary

The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with LIF

  • leukemia inhibitory factor (Lif) antibody
  • leukemia inhibitory factor (LIF) antibody
  • leukemia inhibitory factor (cholinergic differentiation factor) (LIF) antibody
  • leukemia inhibitory factor receptor (Lifr) antibody
  • A230075M04Rik antibody
  • AW061234 antibody
  • CDF antibody
  • DIA antibody
  • HILDA antibody
  • LIF antibody
  • MLPLI antibody

Protein level used designations for LIF

d factor , differentiation-stimulating factor , D factor , cholinergic differentiation factor , differentiation inhibitory activity , differentiation-inducing factor , hepatocyte-stimulating factor III , human interleukin in DA cells , melanoma-derived LPL inhibitor , leukemia inhibitory factor (cholinergic differentiation factor) , cholinergic neuronal differentiation factor , bLIF , leukemia inhibitory factor , D-factor/LIF receptor , LIF receptor , LIF-R , leukemia inhibitory factor receptor alpha chain , soluble differentiation-stimulating factor receptor

GENE ID SPECIES
16878 Mus musculus
3976 Homo sapiens
427718 Gallus gallus
60584 Rattus norvegicus
399503 Sus scrofa
100713602 Cavia porcellus
101110180 Ovis aries
280840 Bos taurus
403449 Canis lupus familiaris
16880 Mus musculus
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