Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Human STAT1 ELISA Kit for Cell ELISA - ABIN2114921
Sharma, Bashir, Ansarullah, Faraz Khan, Ahmad, Khan et al.: Inhibition of Src homology 2 domain containing protein tyrosine phosphatase as the possible mechanism of metformin-assisted amelioration of obesity induced insulin resistance in high fat diet fed ... in Biochemical and biophysical research communications 2017
Human STAT1 ELISA Kit for Cell ELISA - ABIN1981837
Nakano, Fujii, Hashimoto, Yukawa, Yoshifuji, Ohmura, Nakaizumi, Mimori: Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. in Clinical and experimental immunology 2012
Angiotensin II regulates dendritic cells through activation of p65 NF-kappaB (show NFkBP65 ELISA Kits), ERK1 (show MAPK3 ELISA Kits), ERK2 (show MAPK1 ELISA Kits) and STAT1 pathways.
The results provide functional evidence that elevated PDGFRbeta signaling causes tissue wasting or overgrowth reminiscent of human genetic syndromes and that the STAT1 pathway is a crucial modulator of this phenotypic spectrum.
selective knockdown of TNFR5 ameliorates glucolipotoxic induction of STAT1 expression and NF-kappaB (show NFKB1 ELISA Kits) activity.
Treatment of the haplotype Npr1 (show NPR1 ELISA Kits)(+/-) mice with histone deacetylase (show HDAC1 ELISA Kits) inhibitors significantly lowered blood pressure and reduced the renal inflammation and fibrosis involving the interactive roles of HDAC1 (show HDAC1 ELISA Kits)/2, NF-kappaB (show NFKB1 ELISA Kits) (p65 (show NFkBP65 ELISA Kits)), and STAT1.
PHLPP1 (show PHLPP1 ELISA Kits) reduced IFN-gamma (show IFNG ELISA Kits)-stimulated but not LPS (show TLR4 ELISA Kits)-induced ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation, and inhibition of ERK1/2 (show MAPK1/3 ELISA Kits) abolished IFN-gamma-induced (show SAMHD1 ELISA Kits) ser (show SIGLEC1 ELISA Kits)(727) STAT1 phosphorylation and iNOS (show NOS2 ELISA Kits) expression.
Data demonstrate that STAT1 is a key orchestrator of cytokine-producing innate lymphoid cells responses during viral infection via ILC (show CCL27 ELISA Kits)-extrinsic regulation of IL-33 (show IL33 ELISA Kits) and IL-23 (show IL23A ELISA Kits).
NKLAM (show RNF19B ELISA Kits) is a positive regulator of STAT1-mediated transcriptional activity and is an important component of the innate immune response.
In cultured macrophages, LPS (show TLR4 ELISA Kits)-induced expression of monocyte chemoattractant protein (MCP)-1 (show CPT1B ELISA Kits) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (show NFKBIZ ELISA Kits) activities.
Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were used to detect the mRNA and protein expressions of p-p38MAPK (show MAPK14 ELISA Kits), AAT, signal transducer and activator of transcription 1 (STAT1) and activating transcription factor2 (ATF2 (show ATF2 ELISA Kits))
This secreted effector, toxoplasma inhibitor of STAT1-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2 (show CHD4 ELISA Kits)/NuRD to STAT1-dependent promoters, resulting in altered chromatin and blocked transcription.
presentation of the two different cases of a patient and her mother with STAT1 GOF mutations having the occurrence of intracranial aneurysms in common
IL-27 (show IL27 ELISA Kits) stimulation activated STAT1 and STAT3 (show STAT3 ELISA Kits) in HeLa and T98G cells, suggesting that IL-27 (show IL27 ELISA Kits) engages the STAT1/3 pathway, which then leads to the upregulation of IL-6 (show IL6 ELISA Kits), IP-10 (show CXCL10 ELISA Kits), and MIG (show CXCL9 ELISA Kits)
Type-I IFN treatment triggers the interaction of STAT1 with SLFN5 (show SLFN5 ELISA Kits), and the resulting complex negatively controls STAT1-mediated gene transcription via interferon (show IFNA ELISA Kits) stimulated response elements
Results show that the amino acids of STAT1 interacting with the DNA primarily determine the specificity of the proteins.
In this review, we summarize recent progress on the function and regulation of STAT1 in both cancer and insulin (show INS ELISA Kits) resistance diseases. Drugs and small molecules that can interfere with STAT1 activity or expression are also discussed
this study shows that the IFN-beta (show IFNB1 ELISA Kits)/STAT1 pathway is dysregulated in inflammatory bowel disease
MACC1 (show MACC1 ELISA Kits) regulates Fas (show FAS ELISA Kits) mediated apoptosis through STAT1/3 - Mcl-1 (show MCL1 ELISA Kits) signaling in solid cancers.
the phosphorylation of signal transducer and activator of transcription 1 (STAT1-py) was impaired in asthmatics, whereas the phosphorylation of signal transducer and activator of transcription 6 (STAT6 (show STAT6 ELISA Kits)-py) was slightly enhanced.
MFSD2B, CCL20 (show CCL20 ELISA Kits) and STAT1, or STARD7 and ZNF512 (show ZNF512 ELISA Kits) genes may be risk or protect factors in prognosis of ADC (show ADC ELISA Kits); HTR2B (show HTR2B ELISA Kits), DPP4 (show DPP4 ELISA Kits), and TGFBRAP1 (show TGFBRAP1 ELISA Kits) genes may be risk factors in prognosis of SQC (show QPCT ELISA Kits).
Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (show IFNA ELISA Kits) response by inducing STAT1 degradation.
this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets
Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (show JAK3 ELISA Kits)-STAT1) signaling pathway.
Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (show STAT2 ELISA Kits) nuclear translocation.
Nsp1beta inhibits interferon-activated (show MNDA ELISA Kits) STAT1/STAT2 (show STAT2 ELISA Kits) signal transduction by inducing karyopherin-alpha1 degradation.
STAT1 is involved in mediating the action of ghrelin (show GHRL ELISA Kits) on ovarian cell functions.
the majority of the STAT1/STAT2 (show STAT2 ELISA Kits)/IRF9 (show IRF9 ELISA Kits) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked
Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.
Nitric oxide-dependent increase in caspase-8 (show CASP8 ELISA Kits) mRNA levels is associated with phosphorylation of STAT-1 at Ser (show SIGLEC1 ELISA Kits)-727 and STAT1 binding to the caspase-8 (show CASP8 ELISA Kits) promoter in cultured lung endothelial cells.
Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.
Report interferon-tau dependent STAT1 regulation of SOCS (show CISH ELISA Kits) genes in bovine endometrium during estrus cycle and embryo implantation.
the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate
results show for the first time that interleukin-6 (show IL6 ELISA Kits) (IL), in the presence of its soluble receptor (show IFNAR1 ELISA Kits) (sIL (show STIL ELISA Kits)-6R), induces activation of JAK1 (show JAK1 ELISA Kits), JAK2 (show JAK2 ELISA Kits), and STAT1/STAT3 (show STAT3 ELISA Kits) proteins in bovine articular chondrocytes
Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (show CSN2 ELISA Kits) synthesis and fat metabolism.
Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (show STAT2 ELISA Kits).
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 1-alpha/beta
, HAI-2 related small protein
, signal transducer and activator of transcription-1
, transcription factor ISGF-3 components p91/p84
, signal transducer and activator of transcription 4
, signal transducer and activator of transcription 1
, transcription factor ISGF-3
, activator of transcription
, signal transduction