Browse our anti-STAT5A (STAT5A) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 5A Antibodies (STAT5A)
On www.antibodies-online.com are 497 Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies from 39 different suppliers available. Additionally we are shipping STAT5A Kits (43) and STAT5A Proteins (11) and many more products for this protein. A total of 594 STAT5A products are currently listed.
Synonyms:
AA959963, MGF, Stat5, STAT5A, STAT5A/MGF, STATA5
list all antibodies Gene Name GeneID UniProt
STAT5A 6776 P42229
STAT5A 20850 P42230
STAT5A 24918 Q62771

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Top referenced anti-STAT5A Antibodies

  1. Dog (Canine) Monoclonal STAT5A Primary Antibody for IF, IP - ABIN967810 : Buitenhuis, Baltus, Lammers, Coffer, Koenderman: Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells. in Blood 2002 (PubMed)
    Show all 5 references for 967810

  2. Human Monoclonal STAT5A Primary Antibody for WB - ABIN968702 : Gouilleux, Wakao, Mundt, Groner: Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. in The EMBO journal 1994 (PubMed)
    Show all 5 references for 968702

  3. Human Monoclonal STAT5A Primary Antibody for ICS, WB - ABIN968701 : Park, Lee, Frank, Razani, Nguyen, Parlow, Russell, Hulit, Pestell, Lisanti: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. in Molecular biology of the cell 2002 (PubMed)
    Show all 5 references for 968701

  4. Human Polyclonal STAT5A Primary Antibody for EIA, IHC (p) - ABIN358237 : Martens, Uzan, Wery, Hooghe, Hooghe-Peters, Gertler: Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 358237

  5. Human Polyclonal STAT5A Primary Antibody for IHC (p), WB - ABIN196696 : Dentelli, Del Sorbo, Rosso, Molinar, Garbarino, Camussi, Pegoraro, Brizzi: Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 3 references for 196696

  6. Cow (Bovine) Polyclonal STAT5A Primary Antibody for WB - ABIN2780480 : Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: Epigenetic control of rDNA loci in response to intracellular energy status. in Cell 2008 (PubMed)
    Show all 2 references for 2780480

  7. Human Monoclonal STAT5A Primary Antibody for FACS - ABIN4898875 : Kobayashi, Watanabe, Suzuki, Furu, Ito, Ito, Matsuda, Yoshitomi: TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells. in European journal of immunology 2016 (PubMed)

  8. Human Polyclonal STAT5A Primary Antibody for ELISA, WB - ABIN1533730 : Hou, Schindler, Henzel, Wong, McKnight: Identification and purification of human Stat proteins activated in response to interleukin-2. in Immunity 1995 (PubMed)

  9. Human Polyclonal STAT5A Primary Antibody for IF (p), IHC (p) - ABIN738276 : Yang, Sun, Sun, Qi: Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. in Molecular biology reports 2012 (PubMed)

  10. Human Polyclonal STAT5A Primary Antibody for IF, IHC (p) - ABIN389668 : Moreira, Cabezón, Gromova, Gromov, Timmermans-Wielenga, Machado, Llombart-Bosch, Kroman, Rank, Celis: Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. in Molecular oncology 2010 (PubMed)

More Antibodies against STAT5A Interaction Partners

Human Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. Molecular interactions of EphA4 (show EPHA4 Antibodies), growth hormone receptor (show GHR Antibodies), Jak2 (show JAK2 Antibodies), and STAT5B (show STAT5B Antibodies) have been described.

  2. High STAT5 phosphorylation is associated with systemic lupus erythematosus.

  3. NPM1 (show NPM1 Antibodies) downregulation by P-STAT5 is mediated by impairing the BRCA1-BARD1 (show BARD1 Antibodies) ubiquitin ligase, which controls the stability of NPM1 (show NPM1 Antibodies). In turn, decreased NPM1 (show NPM1 Antibodies) levels led to suppression of p53 (show TP53 Antibodies) expression, resulting in enhanced cell survival.

  4. All merkel cell carcinoma (MCC (show MCC Antibodies)) cases with a good outcome expressed pSTAT5B, whereas all MCC (show MCC Antibodies) cases with a poor outcome did not express pSTAT5B; hence, pSTAT5B expression may be an indicator of positive prognosis in patients with MCC (show MCC Antibodies).

  5. High STAT5A expression is associated with B-lymphoblastic lymphoma with inflammation.

  6. Results provide evidence that HDAC6 (show HDAC6 Antibodies) could regulate HMGN2 (show HMGN2 Antibodies) acetylation levels and binding to Stat5a-responsive promoters, and therefore, Stat5a transcriptional activity in breast cancer cells.

  7. Sustained STAT5 transcription factor (STAT5) phosphorylation is necessary to induce long-term interleukin 2 receptor subunit alpha (CD25 (show IL2RA Antibodies)) expression in T lymphocytes.

  8. BCR/ABL (show ABL1 Antibodies) positively regulates the expression of EZH2 (show EZH2 Antibodies) via STAT5 signaling.

  9. these results demonstrate that the oncogenic signal transducer and activator of transcription 5/Akt (show AKT1 Antibodies) pathway is a cellular target for indole-3-carbinol in chronic myeloid leukemia (show BCL11A Antibodies) cells. Thus, this clinically tested natural compound can be a potential candidate in the treatment of chronic myeloid leukemia (show BCL11A Antibodies) following confirmation with clinical studies

  10. elucidate a novel mechanism whereby the linker histone H1 (show H1F0 Antibodies) prevents STAT5 binding at promoter DNA, and the PRL (show PRL Antibodies)-induced dissociation of H1 mediated by HMGN2 (show HMGN2 Antibodies) is necessary to allow full STAT5 recruitment and promote the biological effects of PRL (show PRL Antibodies) signaling

Mouse (Murine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. STAT5 target genes such as Oncostatin M (show OSM Antibodies) were highly expressed in FLT3 (show FLT3 Antibodies)-ITD(+) myeloid but not in FLT3 (show FLT3 Antibodies)-ITD(+) lymphoid progenitor cells; lineage-specific STAT5 activation in hematopoietic progenitor cells predicts the FLT3 (show FLT3 Antibodies)(+)-mediated leukemic phenotype in mice.

  2. findings reveal an essential role for STAT5 in maintaining lipid homeostasis in white adipose tissue and provide a rationale for future studies into the potential of STAT5 manipulation to improve outcomes in metabolic diseases.

  3. deregulation of local signal transducer and activator of transcription 5 signaling augments high fat diet-induced lipid accumulation in both muscle and liver.

  4. Data show that CUZD1 (show CUZD1 Antibodies) interacts with a complex containing JAK1 (show JAK1 Antibodies)/JAK2 (show JAK2 Antibodies) and STAT5, downstream transducers of prolactin (show PRL Antibodies) signaling in the mammary gland.

  5. The study describes an interaction network of STAT5a/LSD1 (show KDM1A Antibodies)/HDAC3 (show HDAC3 Antibodies) and a dual function of LSD1 (show KDM1A Antibodies)/HDAC3 (show HDAC3 Antibodies) on STAT5a-dependent transcription, defined by protein-protein interactions, genomic binding localization/affinity and motifs.

  6. this study shows that lipoxin A4 protects against LPS (show TLR4 Antibodies)-induced sepsis by promoting the generation and migration of splenic innate response activator B cells, and the underlying molecular mechanism may be related to STAT5 activation

  7. Study showed that suppression of STAT3 (show STAT3 Antibodies), STAT5, and STAT6 (show STAT6 Antibodies) and overexpression of the proapoptotic factor STAT1 (show STAT1 Antibodies), which provides p53 (show TP53 Antibodies)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (show ERBB2 Antibodies) tyrosine kinase receptor (show KDR Antibodies) overexpression promotes neuronal survival through activation of STAT (show STAT1 Antibodies)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 Antibodies)

  8. Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 (show ELF5 Antibodies) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (show PRL Antibodies)/p-Stat5 pathway.

  9. Bcl6 (show BCL6 Antibodies) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a axis.

  10. constitutive STAT5 binding to c-Myc (show MYC Antibodies) super-enhancer might contribute to BRD2 (show BRD2 Antibodies) maintenance and thus allow sustained expression of c-Myc (show MYC Antibodies) in Ba/F3 cells transformed by STAT5-1*6.

Pig (Porcine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

Cow (Bovine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  2. Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found

  3. Results indicate that SNPs in STAT5A and JAK2 (show JAK2 Antibodies) genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  4. The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.

  5. INVESTIGATION OF STAT5A, FSHR (show FSHR Antibodies) AND LHR (show LHCGR Antibodies) GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS

  6. The Stat5a gene is associated with an increase in lactation of mammary gland epithelial cells.

  7. STAT5A/AvaI polymorphism seems to be a promising indirect marker to improve milk production traits in cattle.

  8. Associations between reproduction and milk traits, and polymorphisms at the STAT5A and FGF2 (show FGF2 Antibodies) gene loci, were found with STAT5A polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  9. Base sequence variation in STAT5A-noncoding region was studied.

  10. The association of fertilization rate with STAT5A polymorphisms was evaluated in ocytes. Associations were found for 6 and 2 SNP. 5 SNP showed associations with both embryonic survival and fertilization rate compared with 1 SNP.

STAT5A Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5A

  • signal transducer and activator of transcription 5A (STAT5A) antibody
  • signal transducer and activator of transcription 5A (Stat5a) antibody
  • signal transducer and activator of transcription 5A-like (LOC100348518) antibody
  • signal transducer and activator of transcription 5B (STAT5B) antibody
  • AA959963 antibody
  • MGF antibody
  • Stat5 antibody
  • STAT5A antibody
  • STAT5A/MGF antibody
  • STATA5 antibody

Protein level used designations for STAT5A

signal transducer and activator of transcription 5A , signal transducer and activator of transcription 5A-like , mammary gland factor STAT5A , mammary gland factor , signal transducer and activator of transcription 5 , STAT5A, Mammary Gland Factor , transcription factor STAT5B

GENE ID SPECIES
100052904 Equus caballus
454681 Pan troglodytes
574129 Macaca mulatta
100461695 Pongo abelii
6776 Homo sapiens
20850 Mus musculus
24918 Rattus norvegicus
490968 Canis lupus familiaris
397550 Sus scrofa
282375 Bos taurus
100716811 Cavia porcellus
443419 Ovis aries
100348518 Oryctolagus cuniculus
6777 Homo sapiens
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