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Browse our anti-STAT5A (STAT5A) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 5A Antibodies (STAT5A)
On www.antibodies-online.com are 429 Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies from 38 different suppliers available. Additionally we are shipping STAT5A Kits (44) and STAT5A Proteins (11) and many more products for this protein. A total of 527 STAT5A products are currently listed.
Synonyms:
AA959963, MGF, Stat5, STAT5A, STAT5A/MGF, STATA5
list all antibodies Gene Name GeneID UniProt
STAT5A 6776 P42229
STAT5A 20850 P42230
STAT5A 24918 Q62771

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Top referenced anti-STAT5A Antibodies

  1. Dog (Canine) Monoclonal STAT5A Primary Antibody for IF, IP - ABIN967810 : Buitenhuis, Baltus, Lammers, Coffer, Koenderman: Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells. in Blood 2002 (PubMed)
    Show all 5 references for ABIN967810

  2. Human Monoclonal STAT5A Primary Antibody for WB - ABIN968702 : Gouilleux, Wakao, Mundt, Groner: Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. in The EMBO journal 1994 (PubMed)
    Show all 5 references for ABIN968702

  3. Human Polyclonal STAT5A Primary Antibody for EIA, IHC (p) - ABIN358238 : Martens, Uzan, Wery, Hooghe, Hooghe-Peters, Gertler: Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN358238

  4. Human Polyclonal STAT5A Primary Antibody for EIA, IHC (p) - ABIN358237 : Defilippi, Rosso, Dentelli, Calvi, Garbarino, Tarone, Pegoraro, Brizzi: {beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation. in The Journal of cell biology 2005 (PubMed)
    Show all 5 references for ABIN358237

  5. Human Monoclonal STAT5A Primary Antibody for ICS, WB - ABIN968701 : Park, Lee, Frank, Razani, Nguyen, Parlow, Russell, Hulit, Pestell, Lisanti: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. in Molecular biology of the cell 2002 (PubMed)
    Show all 5 references for ABIN968701

  6. Human Polyclonal STAT5A Primary Antibody for EIA, IHC (p) - ABIN401413 : Baugh, Floyd, Stephens: The modulation of STAT5A/GR complexes during fat cell differentiation and in mature adipocytes. in Obesity (Silver Spring, Md.) 2007 (PubMed)
    Show all 4 references for ABIN401413

  7. Human Monoclonal STAT5A Primary Antibody for EIA, IF - ABIN400812 : Burchill, Yang, Vogtenhuber, Blazar, Farrar: IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 4 references for ABIN400812

  8. Cow (Bovine) Polyclonal STAT5A Primary Antibody for WB - ABIN2780480 : Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: Epigenetic control of rDNA loci in response to intracellular energy status. in Cell 2008 (PubMed)
    Show all 2 references for ABIN2780480

  9. Human Polyclonal STAT5A Primary Antibody for IF, IHC (p) - ABIN389668 : Moreira, Cabezón, Gromova, Gromov, Timmermans-Wielenga, Machado, Llombart-Bosch, Kroman, Rank, Celis: Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. in Molecular oncology 2010 (PubMed)

  10. Human Polyclonal STAT5A Primary Antibody for ELISA, WB - ABIN1533730 : Hou, Schindler, Henzel, Wong, McKnight: Identification and purification of human Stat proteins activated in response to interleukin-2. in Immunity 1995 (PubMed)

More Antibodies against STAT5A Interaction Partners

Human Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. STAT5 activation by EGF (show EGF Antibodies) constitutes an important cascade for the regulation of cell proliferation and invasion in trophoblast cells.

  2. Decreased expression of STAT5 was associated with metastases in Colon Carcinoma.

  3. MSM decreased the ability of STAT5b (show STAT5B Antibodies) to bind the promoter of the HER2 (show ERBB2 Antibodies) gene.

  4. PTP1B (show PTPN1 Antibodies) directly regulates STAT5 phosphorylation and its activation via the cAMP/PKA pathway downstream of the 5-HT7 (show HTR7 Antibodies) receptor is involved in the suppression of beta-casein (show CSN2 Antibodies) expression in MCF-12A cells

  5. Foxp3 (show FOXP3 Antibodies) has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) pathway

  6. Results confirm that STAT5B (show STAT5B Antibodies) is mutated in T-PLL and underscore the potential therapeutical relevance of epigenetic regulator.

  7. prolactin (show PRL Antibodies) activation of Stat5 results in the formation of a complex between phospho-Stat5 and BRCA1. Formation of this complex does not interfere with nuclear translocation or binding of BRCA1 to the p21 (show CDKN1A Antibodies) promoter

  8. ABL (show ABL1 Antibodies)-N administration induced apoptosis of PC3 (show PCSK1 Antibodies) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX Antibodies)/Bcl-2 (show BCL2 Antibodies) ratio. Expression of KLF5 (show KLF5 Antibodies), Stat5b (show STAT5B Antibodies) and ICAM-1 (show ICAM1 Antibodies) was significantly downregulated in PC3 (show PCSK1 Antibodies) cells.

  9. The innate immune regulator STAT-5 is shown to regulate transcription of the ATR binding factor TopBP1, and this is critical for the induction of the ATR pathway in human papillomavirus-infected keratinocytes.

  10. The two STAT5 isoforms, STAT5a and STAT5b (show STAT5B Antibodies).

Mouse (Murine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. constitutive STAT5 binding to c-Myc (show MYC Antibodies) super-enhancer might contribute to BRD2 (show BRD2 Antibodies) maintenance and thus allow sustained expression of c-Myc (show MYC Antibodies) in Ba/F3 cells transformed by STAT5-1*6.

  2. Foxp3 (show FOXP3 Antibodies) has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) pathway

  3. transduction of developing Th9 cells with a constitutively active STAT5 eliminates the ability of IL-6 (show IL6 Antibodies) to reduce IL-9 (show IL9 Antibodies) production.

  4. Strong selective advantage for leukemic transformation in the background of Stat5 deficient hematopoiesis was permissive for faster initiation of Myc (show MYC Antibodies)-induced transformation to B (show TDO2 Antibodies)-ALL.

  5. Thrombopoietin (show THPO Antibodies)-mediated phosphorylation of STAT5 triggers its genome-wide relocation to STAT (show STAT1 Antibodies) consensus sites, resulting in loss of a uSTAT5 program that restrains megakaryocytic differentiation and activation of STAT5-driven gene expression.

  6. Transcriptome analysis identified a class of mammary-restricted genes that was particularly dependent on high STAT5 levels as a result of the intergenic enhancer

  7. domain-mapping results showed that both the substrate-interacting and the phosphatase domains of DUSP4 (show DUSP9 Antibodies) were required for its optimal interaction with STAT5, while the coiled-coil domain of STAT5 appeared to hinder this interaction

  8. STAT5 activation by FLT3 (show FLT3 Antibodies)-ITD protects cells treated with the PI3K/Akt (show AKT1 Antibodies) pathway inhibitors from apoptosis by maintaining Mcl-1 (show MCL1 Antibodies) expression through the mTORC1/4EBP1 (show EIF4EBP1 Antibodies)/eIF4E (show EIF4E Antibodies) pathway.

  9. Collectively, the findings show that human beta-cells fail to proliferate in response to PRL (show PRL Antibodies) for multiple reasons, one of which is a paucity of functional PRL (show PRL Antibodies) receptors, and that murine Stat5 overexpression is able to bypass these impediments.

  10. STAT5 signaling is increased in the liver in GH-transgenic mice during the growth period, with a balance between positive and negative effectors resulting in accelerated but controlled growth.

Pig (Porcine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

Cow (Bovine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. Results indicate that SNPs in STAT5A and JAK2 (show JAK2 Antibodies) genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  2. The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.

  3. INVESTIGATION OF STAT5A, FSHR (show FSHR Antibodies) AND LHR (show LHCGR Antibodies) GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS

  4. The Stat5a gene is associated with an increase in lactation of mammary gland epithelial cells.

  5. STAT5A/AvaI polymorphism seems to be a promising indirect marker to improve milk production traits in cattle.

  6. Associations between reproduction and milk traits, and polymorphisms at the STAT5A and FGF2 (show FGF2 Antibodies) gene loci, were found with STAT5A polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  7. Base sequence variation in STAT5A-noncoding region was studied.

  8. The association of fertilization rate with STAT5A polymorphisms was evaluated in ocytes. Associations were found for 6 and 2 SNP. 5 SNP showed associations with both embryonic survival and fertilization rate compared with 1 SNP.

  9. STAT5A affects embryonic survival in a manner influenced by developmental stage and allele parent of origin.

  10. Although more studies are needed to better clarify the role of this SNP on production traits, STAT5A/AvaI polymorphism appears to be a promising indirect marker to improve milk production traits in cattle.

STAT5A Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5A

  • signal transducer and activator of transcription 5A (STAT5A) antibody
  • signal transducer and activator of transcription 5A (Stat5a) antibody
  • signal transducer and activator of transcription 5A-like (LOC100348518) antibody
  • signal transducer and activator of transcription 5B (STAT5B) antibody
  • AA959963 antibody
  • MGF antibody
  • Stat5 antibody
  • STAT5A antibody
  • STAT5A/MGF antibody
  • STATA5 antibody

Protein level used designations for STAT5A

signal transducer and activator of transcription 5A , signal transducer and activator of transcription 5A-like , mammary gland factor STAT5A , mammary gland factor , signal transducer and activator of transcription 5 , STAT5A, Mammary Gland Factor , transcription factor STAT5B

GENE ID SPECIES
100052904 Equus caballus
454681 Pan troglodytes
574129 Macaca mulatta
100461695 Pongo abelii
6776 Homo sapiens
20850 Mus musculus
24918 Rattus norvegicus
490968 Canis lupus familiaris
397550 Sus scrofa
282375 Bos taurus
100716811 Cavia porcellus
443419 Ovis aries
100348518 Oryctolagus cuniculus
6777 Homo sapiens
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