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Browse our JNK (MAPK8) ELISA Kits

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Mitogen-Activated Protein Kinase 8 ELISA Kits (MAPK8)
On are 21 Mitogen-Activated Protein Kinase 8 (MAPK8) ELISA Kits from 9 different suppliers available. Additionally we are shipping JNK Antibodies (402) and JNK Proteins (24) and many more products for this protein. A total of 479 JNK products are currently listed.
AI849689, Bsk, BSK/DJNK, c-Jun, CG5680, D-JNK, D-junk, DBSK/JNK, dJNK, DJNK/bsk, Dmel\\CG5680, jnk, JNK-46, JNK/SAPK, jnk1, JNK1A2, JNK21B1/2, Junk, mapk8, Prkm8, sapk1, SAPK1c, SAPKa, T10F20.15, zgc:112379
list all ELISA KIts Gene Name GeneID UniProt
MAPK8 5599 P45983
MAPK8 26419 Q91Y86
MAPK8 116554 P49185

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JNK (MAPK8) ELISA Kits by Reactivity

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Top referenced JNK ELISA Kits

  1. Human JNK ELISA Kit for Cell ELISA - ABIN1981833 : Hinton, Henderson, Blanks, Rudnicka, Miller: Monoclonal antibodies react with neuronal subpopulations in the human nervous system. in The Journal of comparative neurology 1988 (PubMed)
    Show all 9 references for ABIN1981833

  2. ABIN411896 : Noguchi, Naziruddin, Shimoda, Fujita, Chujo, Takita, Peng, Sugimoto, Itoh, Tamura, Olsen, Kobayashi, Onaca, Levy, Matsumoto: Comparison of fresh and cultured islets from human and porcine pancreata. in Transplantation proceedings 2010 (PubMed)
    Show all 6 references for ABIN411896

  3. ABIN411895 : Shintani, Hollingsworth, Wheelock, Johnson: Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression. in Cancer research 2006 (PubMed)
    Show all 2 references for ABIN411895

More ELISA Kits for JNK Interaction Partners

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. malignant transformation of the ras(V12)scrib(1 (show SCRIB ELISA Kits)) tumors requires bZIP protein Fos, the ETS (show ETS1 ELISA Kits)-domain factor Ets21c and the nuclear receptor Ftz-F1 (show NR5A2 ELISA Kits), all acting downstream of Jun-N-terminal kinase.

  2. Diminished MTORC1-dependent JNK activation underlies the neurodevelopmental defects associated with lysosomal dysfunction.

  3. ROS (show ROS1 ELISA Kits)/JNK/p38 (show MAPK14 ELISA Kits)/Upd (show UROD ELISA Kits) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  4. Significantly, the JNK pathway is responsible for the majority of the phenotypes and transcriptional changes downstream of Notch (show NOTCH1 ELISA Kits)-Src (show SRC ELISA Kits) synergy.

  5. This study demonstrated that the mechanism by which Bsk (show FRK ELISA Kits) is required for pruning is through reducing the membrane levels of the adhesion molecule (show NCAM1 ELISA Kits) Fasciclin II (show NCAM2 ELISA Kits) (FasII)

  6. Study solves the crystal structure of unphosphorylated DJNK in complex with adenylyl imidodiphosphate (AMP (show AMPH ELISA Kits)-PNP (show NP ELISA Kits)) and magnesium.

  7. PERK/ATF4 activated the JNK pathway through Rac1 and Slpr activation in apoptotic cells.

  8. Data show that oxidative stress and neuroinflammation are intrinsic components of TDP-43 (show TARDBP ELISA Kits)-associated neurodegeneration and the balance between cytoprotective JNK and cytotoxic p38 (show MAPK14 ELISA Kits) signaling dictates phenotypic outcome to TDP-43 (show TARDBP ELISA Kits) expression in Drosophila.

  9. Data show that the actin-Capping Protein (show TMOD4 ELISA Kits) (CP) alphabeta heterodimer, which regulates actin (show ACTB ELISA Kits) filament (F-actin (show ACTB ELISA Kits)) polymerization, limits Src (show SRC ELISA Kits)-induced apoptosis or tissue overgrowth by restricting JNK activation.

  10. In a genetic screen, we identified signaling by the EGFR (show EGFR ELISA Kits) pathway as important for apoptosis-induced proliferation acting downstream of JNK signaling

Human Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. MUC1 (show MUC1 ELISA Kits) promotes hepatocellular carcinoma progression and tumorigenesis and mediates autocrine TGF-b signaling by activating the JNK/AP-1 (show FOSB ELISA Kits) pathway in hepatocellular carcinoma cells, and makes MUC1 (show MUC1 ELISA Kits) and JNK as attractive targets for hepatocellular carcinoma therapy.

  2. Allograft tumor assays in mice demonstrate that this mechanism contributes to tumorigenesis driven by mutant IDH1 (show IDH1 ELISA Kits), a result confirmed by detection of JNK inactivation in human gliomas harboring IDH1 (show IDH1 ELISA Kits)-R132H mutations.

  3. Pretreatment by IRE1 (show ERN1 ELISA Kits) agonist tunicamycin or JNK agonist anisomycin attenuated the effect of psoralen on osteoporotic osteoblasts. Psoralen inhibited apoptosis of osteoporotic osteoblasts by regulating IRE1 (show ERN1 ELISA Kits)-ASK1 (show MAP3K5 ELISA Kits)-JNK pathway

  4. Therapeutic interventions of potent and selective inhibitors of JNK might provide promising therapeutic approaches for the treatment of OS, and could improve the survival rate and quality of life of OS patients.

  5. the results obtained from RRD (show DHRS4 ELISA Kits), QPLD, IFD and MD simulations indicated that lead1 might be used as a potent antagonist toward human JNK1 in cancer therapeutics.

  6. Data indicate that STK40 (show STK40 ELISA Kits) was a direct target of microRNA miR (show MLXIP ELISA Kits)-130a, and overexpressing miR (show MLXIP ELISA Kits)-130a significantly upregulated NF-kappaB (show NFKB1 ELISA Kits) p65 (show GORASP1 ELISA Kits), SOX9 (show SOX9 ELISA Kits), JNK and p38MAPK (show MAPK14 ELISA Kits) proteins.

  7. Results suggest that curcumin induced the apoptosis of retinoblastoma Y79 cells through the activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) pathways.

  8. These results suggest that ROCK may be important in IL-1 (show IL1A ELISA Kits)-induced signaling through MKK4 (show MAP2K4 ELISA Kits) to JNK and the activation of p38 MAPK (show MAPK14 ELISA Kits).

  9. High JNK1 expression is associated with hepatocellular carcinoma.

  10. Data show that Jun-N-terminal kinase (JNK)/p38 MAPK (show MAPK14 ELISA Kits) activations are required for signaling pathway underlying the ajoene-induced apoptosis.

Mouse (Murine) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. activation of astrocyte MMP2 (show MMP2 ELISA Kits)/JNK1/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model

  2. JNK1/2-dependent regulation of p66ShcS36 phosphorylation, is reported.

  3. that JNK played roles in nerve regeneration at both early and late phases

  4. Results suggest that activation of JNK in Alzheimer's disease (AD) inhibits insulin (show INS ELISA Kits) signaling which could lead to a decreased expression of VGLUT1 (show SLC17A7 ELISA Kits), therefore contributing to the glutamatergic deficit in AD

  5. The cJun (show JUN ELISA Kits) NH2-terminal kinase contributes to the regulation of hepatic fibroblast growth factor 21 (show FGF21 ELISA Kits) expression during fasting/feeding cycles.

  6. JNK kinase is critical for mitochondrial function during reperfusion after myocardial ischemia.

  7. Activated JNK promotes mitochondrial dysfunction and acute hepatotoxicity through robust phosphorylation of numerous mitochondrial proteins.

  8. Reactive oxygen species induce autophagy to counteract apoptosis in mesenchymal stem cells by activation of JNK.

  9. In hepatocytes, JNK1 and JNK2 (show MAPK9 ELISA Kits) appear to have combined effects in protecting from drug-induced liver injury.

  10. The findings suggest that JNK and P38 (show CRK ELISA Kits) could be key regulatory element for Fam83h (show FAM83H ELISA Kits) expression, and that LS8 cells can respond to fluoride by down-regulating Fam83h (show FAM83H ELISA Kits) expression through the regulation of JNK and p38 (show CRK ELISA Kits) signaling pathways.

Xenopus laevis Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3 (show CASP3 ELISA Kits)-dependent Proteolysis of JNK1-2 and Bid (show BID ELISA Kits).

  2. JNK signaling is required to establish microtubule stability and maintain tissue cohesion in the gut (show GUSB ELISA Kits).

  3. Data show that the death pathway is independent of ERK (show MAPK1 ELISA Kits) but relies on activating Bad phosphorylation through the control of both kinases Cdk1 (show CDK1 ELISA Kits) and JNK.

Arabidopsis thaliana Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. study reports MPK8 connects protein phosphorylation, Ca(2 (show CA2 ELISA Kits))+ and ROS (show ROS1 ELISA Kits) in wound-signaling pathway; suggests 2 major activation modes, Ca(2 (show CA2 ELISA Kits))+/CaMs and MAP kinase (show MAPK1 ELISA Kits) phosphorylation cascade, converge at MPK8 to monitor or maintain an essential part of ROS (show ROS1 ELISA Kits) homeostasis

Zebrafish Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein

  2. P38 (show MAPK14 ELISA Kits) and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.

  3. A dorsalization pathway that is exerted by Axin (show AXIN1 ELISA Kits)/JNK signaling and its inhibitor Aida (show AIDA ELISA Kits) during vertebrate embryogenesis, is defined.

  4. JNK-Mmp13 (show MMP13 ELISA Kits) signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Caenorhabditis elegans (C. elegans) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. JNK-1 directly interacts with and phosphorylates DAF-16. Moreover, in response to heat stress, JNK-1 promotes the translocation of DAF-16 into the nucleus.

  2. The present study shows in Caenorhabditis elegans that ambient temperature (1-37 degrees C) specifically influences the activation (phosphorylation) of the MAP kinase JNK-1 as well as the nuclear translocation of DAF-16.

  3. the stress response is controlled by a c-Jun N-terminal kinase (JNK)-like mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) signaling pathway, which is regulated by MLK-1 MAPK (show MAPK1 ELISA Kits) kinase kinase (MAPKKK), MEK-1 (show MAP2K1 ELISA Kits) MAPK (show MAPK1 ELISA Kits) kinase (MAPKK), and KGB-1 (show KCNJ3 ELISA Kits) JNK-like MAPK (show MAPK1 ELISA Kits).

JNK (MAPK8) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with JNK (MAPK8)

  • basket (bsk) Elisa Kit
  • mitogen-activated protein kinase 8 (MAPK8) Elisa Kit
  • mitogen-activated protein kinase 8 (Mapk8) Elisa Kit
  • mitogen-activated protein kinase 8 (mapk8) Elisa Kit
  • mitogen-activated protein kinase 8 (ATMPK8) Elisa Kit
  • mitogen-activated protein kinase 8b (mapk8b) Elisa Kit
  • Protein JNK-1 (jnk-1) Elisa Kit
  • AI849689 Elisa Kit
  • Bsk Elisa Kit
  • BSK/DJNK Elisa Kit
  • c-Jun Elisa Kit
  • CG5680 Elisa Kit
  • D-JNK Elisa Kit
  • D-junk Elisa Kit
  • DBSK/JNK Elisa Kit
  • dJNK Elisa Kit
  • DJNK/bsk Elisa Kit
  • Dmel\\CG5680 Elisa Kit
  • jnk Elisa Kit
  • JNK-46 Elisa Kit
  • JNK/SAPK Elisa Kit
  • jnk1 Elisa Kit
  • JNK1A2 Elisa Kit
  • JNK21B1/2 Elisa Kit
  • Junk Elisa Kit
  • mapk8 Elisa Kit
  • Prkm8 Elisa Kit
  • sapk1 Elisa Kit
  • SAPK1c Elisa Kit
  • SAPKa Elisa Kit
  • T10F20.15 Elisa Kit
  • zgc:112379 Elisa Kit

Protein level used designations for MAPK8

CG5680-PB , CG5680-PE , CG5680-PF , JNK , JUN kinase , Jun N-terminal kinase , Jun NH2-terminal kinase , Jun-N-terminal kinase , Jun-kinase , bsk-PB , bsk-PE , bsk-PF , c-Jun N-terminal kinase , c-Jun aminoterminal kinase , c-Jun-N-terminal kinase , drosophila JNK , JUN N-terminal kinase , MAP kinase 8 , c-Jun N-terminal kinase 1 , mitogen-activated protein kinase 8 isoform JNK1 alpha1 , mitogen-activated protein kinase 8 isoform JNK1 beta2 , stress-activated protein kinase 1 , stress-activated protein kinase 1c , JNK1 beta1 protein kinase , MAPK 8 , mitogen activated protein kinase 8 , protein kinase mitogen-activated 8 , stress-activated protein kinase JNK1 , SAPK gamma , c-jun NH2-terminal kinase , p54 gamma , jnk1a-1 , mitogen-activated protein kinase 8

44801 Drosophila melanogaster
5599 Homo sapiens
26419 Mus musculus
116554 Rattus norvegicus
379876 Xenopus laevis
838394 Arabidopsis thaliana
65236 Danio rerio
177460 Caenorhabditis elegans
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