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Browse our JNK (MAPK8) ELISA Kits

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Mitogen-Activated Protein Kinase 8 ELISA Kits (MAPK8)
On are 23 Mitogen-Activated Protein Kinase 8 (MAPK8) ELISA Kits from 10 different suppliers available. Additionally we are shipping JNK Antibodies (395) and JNK Proteins (25) and many more products for this protein. A total of 476 JNK products are currently listed.
AI849689, Bsk, BSK/DJNK, c-Jun, CG5680, D-JNK, D-junk, DBSK/JNK, dJNK, DJNK/bsk, Dmel\\CG5680, jnk, JNK-46, JNK/SAPK, jnk1, JNK1A2, JNK21B1/2, Junk, mapk8, Prkm8, sapk1, SAPK1c, SAPKa, T10F20.15, zgc:112379
list all ELISA KIts Gene Name GeneID UniProt
MAPK8 5599 P45983
MAPK8 26419 Q91Y86
MAPK8 116554 P49185

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JNK (MAPK8) ELISA Kits by Reactivity

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Top referenced JNK ELISA Kits

  1. Human JNK ELISA Kit for Cell ELISA - ABIN1981833 : Hinton, Henderson, Blanks, Rudnicka, Miller: Monoclonal antibodies react with neuronal subpopulations in the human nervous system. in The Journal of comparative neurology 1988 (PubMed)
    Show all 9 references for ABIN1981833

  2. ABIN411896 : Noguchi, Naziruddin, Shimoda, Fujita, Chujo, Takita, Peng, Sugimoto, Itoh, Tamura, Olsen, Kobayashi, Onaca, Levy, Matsumoto: Comparison of fresh and cultured islets from human and porcine pancreata. in Transplantation proceedings 2010 (PubMed)
    Show all 6 references for ABIN411896

  3. ABIN411895 : Shintani, Hollingsworth, Wheelock, Johnson: Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression. in Cancer research 2006 (PubMed)
    Show all 2 references for ABIN411895

More ELISA Kits for JNK Interaction Partners

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. n addition to significantly increasing the number of JNK target genes identified so far, our results reveal that the LE is a highly heterogeneous morphogenetic organizer, sculpted through crosstalk between JNK, segmental and AP signalling. This fine-tuning regulatory mechanism is essential to coordinate morphogenesis and dynamics of tissue sealing

  2. malignant transformation of the ras(V12)scrib(1 (show SCRIB ELISA Kits)) tumors requires bZIP protein Fos, the ETS (show ETS1 ELISA Kits)-domain factor Ets21c and the nuclear receptor Ftz-F1 (show NR5A2 ELISA Kits), all acting downstream of Jun-N-terminal kinase.

  3. Diminished MTORC1-dependent JNK activation underlies the neurodevelopmental defects associated with lysosomal dysfunction.

  4. ROS (show ROS1 ELISA Kits)/JNK/p38 (show MAPK14 ELISA Kits)/Upd (show UROD ELISA Kits) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  5. Significantly, the JNK pathway is responsible for the majority of the phenotypes and transcriptional changes downstream of Notch (show NOTCH1 ELISA Kits)-Src (show SRC ELISA Kits) synergy.

  6. This study demonstrated that the mechanism by which Bsk (show FRK ELISA Kits) is required for pruning is through reducing the membrane levels of the adhesion molecule (show NCAM1 ELISA Kits) Fasciclin II (show NCAM2 ELISA Kits) (FasII)

  7. Study solves the crystal structure of unphosphorylated DJNK in complex with adenylyl imidodiphosphate (AMP (show AMPH ELISA Kits)-PNP (show NP ELISA Kits)) and magnesium.

  8. PERK/ATF4 activated the JNK pathway through Rac1 and Slpr activation in apoptotic cells.

  9. Data show that oxidative stress and neuroinflammation are intrinsic components of TDP-43 (show TARDBP ELISA Kits)-associated neurodegeneration and the balance between cytoprotective JNK and cytotoxic p38 (show MAPK14 ELISA Kits) signaling dictates phenotypic outcome to TDP-43 (show TARDBP ELISA Kits) expression in Drosophila.

  10. Data show that the actin-Capping Protein (show TMOD4 ELISA Kits) (CP) alphabeta heterodimer, which regulates actin (show ACTB ELISA Kits) filament (F-actin (show ACTB ELISA Kits)) polymerization, limits Src (show SRC ELISA Kits)-induced apoptosis or tissue overgrowth by restricting JNK activation.

Human Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. The increase in c-Jun N-terminal kinase (c-Jun) and specificity protein 1 (SP1 (show SP1 ELISA Kits)) expressions was positively correlated with transforming growth factor beta 1 (TGFbeta1 (show TGFB1 ELISA Kits)) in both high glucose-treated renal mesangial cells (HRMCs) and diabetic kidneys.

  2. JNK1 physically and functionally interacted with VDR (show CYP27B1 ELISA Kits) and positively regulated VDR (show CYP27B1 ELISA Kits) expression at transcriptional and translational levels, which influenced calcitriol-mediated inhibition of cancer cell proliferation.

  3. In conclusion, our findings revealed DIP2 (show WDR3 ELISA Kits) as a novel effector downstream of Bsk (show FRK ELISA Kits) modulating the direction of axon projection.

  4. The release of infectious respiratory syncytial virus (RSV) virions from infected cells was significantly reduced by JNK1/2 siRNA knockdown, implicating JNK1/2 as a key host factor for RSV virus production.

  5. dMyc has an essential role in preventing JNK-mediated retinal glial activation

  6. the results identify the JNK/S6K1 (show RPS6KB1 ELISA Kits) axis as a key molecular mechanism whereby a high fat/sucrose diet impairs insulin (show INS ELISA Kits) action in retina.

  7. PXR (show NR1I2 ELISA Kits) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (show MYLK ELISA Kits) expression and JNK1/2 activation

  8. hese results indicate that DHA induces apoptosis of BGC-823 cells through JNK1/2 and p38 MAPK (show MAPK14 ELISA Kits) signaling pathways and DHA could serve as a potential additional chemotherapeutic agent for treatment of gastric cancer.

  9. MUC1 (show MUC1 ELISA Kits) promotes hepatocellular carcinoma progression and tumorigenesis and mediates autocrine TGF-b signaling by activating the JNK/AP-1 (show FOSB ELISA Kits) pathway in hepatocellular carcinoma cells, and makes MUC1 (show MUC1 ELISA Kits) and JNK as attractive targets for hepatocellular carcinoma therapy.

  10. Allograft tumor assays in mice demonstrate that this mechanism contributes to tumorigenesis driven by mutant IDH1 (show IDH1 ELISA Kits), a result confirmed by detection of JNK inactivation in human gliomas harboring IDH1 (show IDH1 ELISA Kits)-R132H mutations.

Mouse (Murine) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. These data provide evidence for involvement of the TNF-alpha (show TNF ELISA Kits)-JNK axis in extracellular matrix remodeling.

  2. Phosphorylation levels of P38 (show CRK ELISA Kits) and JNK in siRNA-TMEM16A (show ANO1 ELISA Kits) group were lower than that of the Model group. Thus, TMEM16A (show ANO1 ELISA Kits) is one of the critical components of a signal transduction pathway that links renal injury to podocyte apoptosis in DN.

  3. Loss of Jnk1, but not Jnk2 (show MAPK9 ELISA Kits), in macrophages protects them from apoptosis, increasing cell survival, and this accelerates early atherosclerosis in LDL receptor (show LDLR ELISA Kits) knockout mice.

  4. Data indicate that in baicalein (BAI)-treated groups following AngII-infusion, p38-MAPK (show MAPK14 ELISA Kits) and JNK signaling were attenuated

  5. JNK1 physically and functionally interacted with VDR (show CYP27B1 ELISA Kits) and positively regulated VDR (show CYP27B1 ELISA Kits) expression at transcriptional and translational levels, which influenced calcitriol-mediated inhibition of cancer cell proliferation.

  6. data suggest that c-Jun-N-terminal kinase 1 may be recruited by nicotine and is functionally necessary for the acute effects of nicotine on learning and memory.

  7. the results identify the JNK/S6K1 (show RPS6KB1 ELISA Kits) axis as a key molecular mechanism whereby a high fat/sucrose diet impairs insulin (show INS ELISA Kits) action in retina.

  8. MOR (show OPRM1 ELISA Kits) epigenetic regulation requires multiple coordinated signals converging at the MOR (show OPRM1 ELISA Kits) promoter, involving mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) activation and mitogen- and stress-activated protein kinase 1 (show RPS6KA5 ELISA Kits).

  9. activation of astrocyte MMP2 (show MMP2 ELISA Kits)/JNK1/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model

  10. JNK1/2-dependent regulation of p66ShcS36 phosphorylation, is reported.

Xenopus laevis Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3 (show CASP3 ELISA Kits)-dependent Proteolysis of JNK1-2 and Bid (show BID ELISA Kits).

  2. JNK signaling is required to establish microtubule stability and maintain tissue cohesion in the gut (show GUSB ELISA Kits).

  3. Data show that the death pathway is independent of ERK (show MAPK1 ELISA Kits) but relies on activating Bad phosphorylation through the control of both kinases Cdk1 (show CDK1 ELISA Kits) and JNK.

Arabidopsis thaliana Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. study reports MPK8 connects protein phosphorylation, Ca(2 (show CA2 ELISA Kits))+ and ROS (show ROS1 ELISA Kits) in wound-signaling pathway; suggests 2 major activation modes, Ca(2 (show CA2 ELISA Kits))+/CaMs and MAP kinase (show MAPK1 ELISA Kits) phosphorylation cascade, converge at MPK8 to monitor or maintain an essential part of ROS (show ROS1 ELISA Kits) homeostasis

Zebrafish Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein

  2. P38 (show MAPK14 ELISA Kits) and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.

  3. A dorsalization pathway that is exerted by Axin (show AXIN1 ELISA Kits)/JNK signaling and its inhibitor Aida (show AIDA ELISA Kits) during vertebrate embryogenesis, is defined.

  4. JNK-Mmp13 (show MMP13 ELISA Kits) signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Caenorhabditis elegans (C. elegans) Mitogen-Activated Protein Kinase 8 (MAPK8) interaction partners

  1. Our genetic study unravelled the underlying pathway where JNK-1 is acting independently of insulin (show INS ELISA Kits)-IGF-1 (show IGF1 ELISA Kits) signalling (IIS) pathway to modulate longevity. In support of in vivo results in silico docking study of UA with C. elegans JNK-1 ATP-binding site suggested promising binding affinity exhibiting binding energy of -8.11 kcalmol(-1). UA induced JNK-1 activation in wild-type animals underlie the importance of pharmacologi

  2. JNK-1 directly interacts with and phosphorylates DAF-16. Moreover, in response to heat stress, JNK-1 promotes the translocation of DAF-16 into the nucleus.

  3. The present study shows in Caenorhabditis elegans that ambient temperature (1-37 degrees C) specifically influences the activation (phosphorylation) of the MAP kinase JNK-1 as well as the nuclear translocation of DAF-16.

  4. the stress response is controlled by a c-Jun N-terminal kinase (JNK)-like mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) signaling pathway, which is regulated by MLK-1 MAPK (show MAPK1 ELISA Kits) kinase kinase (MAPKKK), MEK-1 (show MAP2K1 ELISA Kits) MAPK (show MAPK1 ELISA Kits) kinase (MAPKK), and KGB-1 (show KCNJ3 ELISA Kits) JNK-like MAPK (show MAPK1 ELISA Kits).

JNK (MAPK8) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with JNK (MAPK8)

  • basket (bsk) Elisa Kit
  • mitogen-activated protein kinase 8 (MAPK8) Elisa Kit
  • mitogen-activated protein kinase 8 (Mapk8) Elisa Kit
  • mitogen-activated protein kinase 8 (mapk8) Elisa Kit
  • mitogen-activated protein kinase 8 (ATMPK8) Elisa Kit
  • mitogen-activated protein kinase 8b (mapk8b) Elisa Kit
  • Protein JNK-1 (jnk-1) Elisa Kit
  • AI849689 Elisa Kit
  • Bsk Elisa Kit
  • BSK/DJNK Elisa Kit
  • c-Jun Elisa Kit
  • CG5680 Elisa Kit
  • D-JNK Elisa Kit
  • D-junk Elisa Kit
  • DBSK/JNK Elisa Kit
  • dJNK Elisa Kit
  • DJNK/bsk Elisa Kit
  • Dmel\\CG5680 Elisa Kit
  • jnk Elisa Kit
  • JNK-46 Elisa Kit
  • JNK/SAPK Elisa Kit
  • jnk1 Elisa Kit
  • JNK1A2 Elisa Kit
  • JNK21B1/2 Elisa Kit
  • Junk Elisa Kit
  • mapk8 Elisa Kit
  • Prkm8 Elisa Kit
  • sapk1 Elisa Kit
  • SAPK1c Elisa Kit
  • SAPKa Elisa Kit
  • T10F20.15 Elisa Kit
  • zgc:112379 Elisa Kit

Protein level used designations for MAPK8

CG5680-PB , CG5680-PE , CG5680-PF , JNK , JUN kinase , Jun N-terminal kinase , Jun NH2-terminal kinase , Jun-N-terminal kinase , Jun-kinase , bsk-PB , bsk-PE , bsk-PF , c-Jun N-terminal kinase , c-Jun aminoterminal kinase , c-Jun-N-terminal kinase , drosophila JNK , JUN N-terminal kinase , MAP kinase 8 , c-Jun N-terminal kinase 1 , mitogen-activated protein kinase 8 isoform JNK1 alpha1 , mitogen-activated protein kinase 8 isoform JNK1 beta2 , stress-activated protein kinase 1 , stress-activated protein kinase 1c , JNK1 beta1 protein kinase , MAPK 8 , mitogen activated protein kinase 8 , protein kinase mitogen-activated 8 , stress-activated protein kinase JNK1 , SAPK gamma , c-jun NH2-terminal kinase , p54 gamma , jnk1a-1 , mitogen-activated protein kinase 8

44801 Drosophila melanogaster
5599 Homo sapiens
26419 Mus musculus
116554 Rattus norvegicus
379876 Xenopus laevis
838394 Arabidopsis thaliana
65236 Danio rerio
177460 Caenorhabditis elegans
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