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Browse our anti-MAP3K5 (MAP3K5) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 Antibodies (MAP3K5)
On are 368 Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies from 29 different suppliers available. Additionally we are shipping MAP3K5 Kits (44) and MAP3K5 Proteins (9) and many more products for this protein. A total of 448 MAP3K5 products are currently listed.
7420452D20Rik, ASK, ASK1, MAP3K5, MAPKKK5, MEKK5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11
list all antibodies Gene Name GeneID UniProt
MAP3K5 293015 O35099
MAP3K5 4217 Q99683

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Most Popular Reactivities for anti-MAP3K5 (MAP3K5) Antibodies

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anti-Mouse (Murine) MAP3K5 Antibodies:

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Top referenced anti-MAP3K5 Antibodies

  1. Human Polyclonal MAP3K5 Primary Antibody for WB - ABIN116930 : Matsuzawa, Ichijo: Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1. in Journal of biochemistry 2001 (PubMed)
    Show all 14 references for ABIN116930

  2. Human Monoclonal MAP3K5 Primary Antibody for IF, WB - ABIN393594 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393594

  3. Human Polyclonal MAP3K5 Primary Antibody for IF, IHC (p) - ABIN197326 : Zhang, Zheng, Storz, Min: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for ABIN197326

  4. Human Polyclonal MAP3K5 Primary Antibody for EIA, IF - ABIN499345 : Ichijo, Nishida, Irie, ten Dijke, Saitoh, Moriguchi, Takagi, Matsumoto, Miyazono, Gotoh: Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 3 references for ABIN499345

  5. Human Polyclonal MAP3K5 Primary Antibody for EIA, IHC (p) - ABIN360294 : Min, Lin, Tang, Yu, Zhang, Wan, Luhn, Fu, Chen: AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation. in Circulation research 2008 (PubMed)
    Show all 3 references for ABIN360294

  6. Human Polyclonal MAP3K5 Primary Antibody for EIA, WB - ABIN360295 : Li, Luo, Yu, Lin, Luo, Zhang, He, Kim, Kim, Tang, Min: SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis. in Cell death and differentiation 2008 (PubMed)
    Show all 3 references for ABIN360295

  7. Human Polyclonal MAP3K5 Primary Antibody for IF, IHC (p) - ABIN197310 : Mabuchi, Ohmichi, Kimura, Nishio, Arimoto-Ishida, Yada-Hashimoto, Tasaka, Murata: Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. in Endocrinology 2003 (PubMed)
    Show all 3 references for ABIN197310

  8. Human Polyclonal MAP3K5 Primary Antibody for IHC, ELISA - ABIN1531773 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1531773

  9. Human Polyclonal MAP3K5 Primary Antibody for IF (p), IHC (p) - ABIN683128 : Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity. in Pancreas 2015 (PubMed)

More Antibodies against MAP3K5 Interaction Partners

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. ASK1 signalling regulates brown and beige (show LYST Antibodies) adipocyte function.

  2. blocking MPTP (show PTPN2 Antibodies)-mediated TNF (show TNF Antibodies) signaling through intrathecal administration of TNF (show TNF Antibodies)-neutralizing antibody prevented Trx1 (show TXN Antibodies) oxidation and downstream ASK1-p38 MAPK (show MAPK14 Antibodies) activation

  3. ASK1 deletion in vivo significantly suppresses hyperoxia-induced elevation of inflammatory cytokines (i.e. IL-1beta (show IL1B Antibodies) and TNF-alpha (show TNF Antibodies)), cell apoptosis in the lung, and recruitment of immune cells

  4. data highlight the importance of ASK1/p38 MAPK (show MAPK14 Antibodies) pathway in the brain and identify Klotho (show KL Antibodies) as a possible anti-oxidant effector

  5. Data show that deletion of eith (show MAP3K6 Antibodies)er MAPKKK5 ASK1 or MAPKKK6 ASK2 in mice promoted the replication of influenza A virus in the lung.

  6. Our results provided the evidence that high-fat diet itself causes cognitive impairment and ASK1 participates in such cognitive impairment.

  7. ASK1 may mediate the teratogenicity of diabetes through activating the JNK1 (show MAPK8 Antibodies)/2-ER stress pathway and inhibiting cell cycle progression, thereby impeding the cardiogenesis pathways essential for ventricular septation and outflow tract development.

  8. Study demonstrates that ASK1 is not involved in beta-cell function and dysfunction but controls stress-induced beta-cell death.

  9. ASK1 in sensitized CD41 T cells appears to play a major role in CHS (show LYST Antibodies) by facilitating IL-17 (show IL17A Antibodies) production.

  10. Because the phosphorylation site mutants of NR4A2 (show NR4A2 Antibodies) cannot rescue the cell death-promoting activity, ASK1-p38 (show CRK Antibodies) pathway-dependent phosphorylation and subsequent cytoplasmic translocation of NR4A2 (show NR4A2 Antibodies) may be required for oxidative stress-induced (show SQSTM1 Antibodies) cell death.

Human Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. ASK1 signalling regulates brown and beige (show LYST Antibodies) adipocyte function.

  2. These results implicate the TNF (show TNF Antibodies)/TRAF2 (show TRAF2 Antibodies)/ASK1/p38 (show CRK Antibodies) kinase pathway in modulating risk of pulmonary complications.

  3. The present findings thus support our notion that ROR1 (show ROR1 Antibodies) sustains lung adenocarcinoma survival, at least in part, through direct physical interaction with ASK1

  4. Together, we suggest that 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to potently inhibit human HCC (show FAM126A Antibodies) cells.

  5. Data show that the MAPKKK6 ASK2 (show MAP3K6 Antibodies), a modulator of MAPKKK5 ASK1 signaling, was essential for ASK1-dependent apoptosis, but not for inducing interferon-beta (IFNB (show IFNB1 Antibodies)) expression.

  6. The expression of ASK1 is correlated with the level of claudin-6 (show CLDN6 Antibodies) in cervical carcinoma cells and tissues.

  7. ASK1 stabilizes APOBEC3G (show APOBEC3G Antibodies) and binds HIV-1 Vif (show BTG1 Antibodies), disrupting assemble of the Vif (show BTG1 Antibodies)-ubiquitin ligase complex, thus restoring the antiviral activity of APOBEC3g (show APOBEC3G Antibodies).

  8. Data indicates that ASK1 expression is regulated by MiR (show MLXIP Antibodies)-19a by targeting specific sites in the 3' untranslated region of its mRNA.

  9. Findings suggest that methyl isocyanate inhibits angiogenesis by inducing mitogen-activated protein kinase kinase kinase 5 ASK1-JNK (show MAPK8 Antibodies)-dependent endothelial cell death.

  10. TNF-alpha (show TNF Antibodies)-induced ASK1-p38 (show CRK Antibodies)/JNK (show MAPK8 Antibodies) pathway is an important mediator of cytokine synthesis and enhanced expression of adhesion molecules in rheumatoid arthritis and is inhibited by thymoquinone.

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. These results indicate an important regulatory role of ASK1 in porcine circovirus type 2-induced apoptotic responses.

  2. PP2A (show PPP2R2B Antibodies) and AIP1 (show PDCD6IP Antibodies) cooperatively induce activation of ASK1-JNK (show MAPK8 Antibodies) signaling and vascular endothelial cell apoptosis.

MAP3K5 Antigen Profile

Antigen Summary

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK.

Alternative names and synonyms associated with MAP3K5

  • mitogen-activated protein kinase kinase kinase 5 (Map3k5) antibody
  • mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) antibody
  • mitogen-activated protein kinase kinase kinase 5 (MAP3K5) antibody
  • 7420452D20Rik antibody
  • ASK antibody
  • ASK1 antibody
  • MAP3K5 antibody
  • MAPKKK5 antibody
  • MEKK5 antibody
  • mitogen-activated protein kinase kinase kinase 5 antibody
  • MUD21.11 antibody
  • MUD21_11 antibody

Protein level used designations for MAP3K5

ASK-1 , MAPK/ERK kinase kinase 5 , MEK kinase 5 , MEKK 5 , apoptosis signal-regulating kinase 1 , mitogen activated protein kinase kinase kinase 5 , MAP/ERK kinase kinase 5 , apoptosis signal regulating kinase 1 , mitogen-activated protein kinase kinase kinase 5

293015 Mus musculus
836819 Arabidopsis thaliana
4217 Homo sapiens
26408 Mus musculus
100157454 Sus scrofa
537380 Bos taurus
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