Browse our MCL-1 (MCL1) ELISA Kits

Full name:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 ELISA Kits (MCL1)
On www.antibodies-online.com are 21 Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) ELISA Kits from 12 different suppliers available. Additionally we are shipping MCL-1 Antibodies (340) and MCL-1 Proteins (13) and many more products for this protein. A total of 394 MCL-1 products are currently listed.
Synonyms:
AW556805, bcl2-L-3, BCL2L3, EAT, mcl-1, MCL1-ES, mcl1/EAT, MCL1L, MCL1S, TM

More ELISA Kits for MCL-1 Interaction Partners

Mouse (Murine) Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) interaction partners

  1. miR (show MLXIP ELISA Kits)-32/MCL-1 pathway members were identified as key early genetic events driving melanoma progression.

  2. GSK3B (show GSK3b ELISA Kits)-MCL1 signaling to regulate axonal autophagy might be important for the successful completion of Wallerian degeneration.

  3. Specific downregulation of Mcl-1 significantly increases apoptosis of peritoneal macrophages and that the MAPK (show MAPK1 ELISA Kits) signaling pathway is the primary mediator of Mcl-1 expression.

  4. MCL1 plays a pivotal role in Leydig-cell steroidogenesis, and might provide novel insights into metabolic regulation in this cell

  5. Although loss of one Mcl-1 allele did not noticeably impair the survival of normal B lymphoid cells, it markedly diminished the survival of Proto-Oncogene (show RAB1A ELISA Kits) Proteins c-myc (show MYC ELISA Kits) overexpressing B cell progenitors.

  6. MCL-1 loss in early B-lymphoid progenitors delayed MYC (show MYC ELISA Kits)-driven lymphomagenesis.

  7. High Mcl-1 levels enhanced mTOR (show FRAP1 ELISA Kits) phosphorylation and augmented the differentiation of terminal effector cells and effector memory CD8 (show CD8A ELISA Kits) T cells.

  8. Data suggest Leishmania donovani exploits host anti-apoptotic protein MCL-1 to prevent apoptosis of host macrophages upon treatment with antiparasitic agents; thus, L. donovani protects its host, a factor in progression of visceral leishmaniasis.

  9. Data demonstrate that soluble factors from MM cells are able to generate MDSC through Mcl-1 upregulation.

  10. a mechanism of inverse coregulation between BECN1 (show BECN1 ELISA Kits) and MCL1 significantly contributes to their opposing roles in tumorigenesis

Human Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) interaction partners

  1. dual inhibition of Mcl-1 via decreased expression and the induction of its antagonist NOXA (show PMAIP1 ELISA Kits) by the combination of carfilzomib and TG02 is active in myeloma

  2. Our findings establish a pivotal role for Mcl-1 degradation in the response of colon cancer cells to targeted therapeutics, and they provide a useful rational platform to develop Mcl-1-targeting agents that can overcome drug resistance

  3. comparison of patient samples prior to and following sunitinib treatment suggested that increases in MCL-1 levels and mTORC1 activity correlate with resistance to sunitinib in patients.

  4. Overexpression of catalytically-active Akt (show AKT1 ELISA Kits) or knockdown of glycogen synthase kinase-3 (GSK3)-beta (show GSK3b ELISA Kits), a substrate for Akt (show AKT1 ELISA Kits), had little effect on Mcl-1 downregulation caused by S6K2 (show RPS6KB2 ELISA Kits) deficiency

  5. review summarizes the role of MCL-1 in B- and T-cell lymphoma

  6. Inhibition of SPHK1 (show SPHK1 ELISA Kits) in human acute myeloid leukemia (show BCL11A ELISA Kits) cells induces MCL1 degradation and caspase (show CASP3 ELISA Kits)-dependent cell death.

  7. bone marrow stroma is capable of inducing Mcl-1 dependence through the production of the plasma cell survival cytokine interleukin-6 (IL-6 (show IL6 ELISA Kits)).

  8. Mcl-1 is required for endothelial cell survival and the regulation of Ang II (show AGT ELISA Kits)-induced endothelial cell death.

  9. Repression of Mcl-1 and disruption of the Mcl-1/Bak (show BAK1 ELISA Kits) interaction in myeloma cells couple ER stress to mitochondrial apoptosis triggered by thapsigargin.

  10. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1) expression and c-Jun N-terminal kinase 1 (JNK1 (show MAPK8 ELISA Kits)) activation and subsequent Bcl-xL (show BCL2L1 ELISA Kits) protein degradation.

MCL-1 (MCL1) Antigen Profile

Antigen Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Alternative names and synonyms associated with MCL-1 (MCL1)

  • myeloid cell leukemia sequence 1 (Mcl1) Elisa Kit
  • myeloid cell leukemia sequence 1 (BCL2-related) (MCL1) Elisa Kit
  • AW556805 Elisa Kit
  • bcl2-L-3 Elisa Kit
  • BCL2L3 Elisa Kit
  • EAT Elisa Kit
  • mcl-1 Elisa Kit
  • MCL1-ES Elisa Kit
  • mcl1/EAT Elisa Kit
  • MCL1L Elisa Kit
  • MCL1S Elisa Kit
  • TM Elisa Kit

Protein level used designations for MCL1

bcl-2-related protein EAT/mcl1 , induced myeloid leukemia cell differentiation protein Mcl-1 homolog , bcl-2-like protein 3 , induced myeloid leukemia cell differentiation protein Mcl-1 , myeloid cell leukemia ES , myeloid cell leukemia protein 1

GENE ID SPECIES
17210 Mus musculus
60430 Rattus norvegicus
4170 Homo sapiens
403537 Canis lupus familiaris
493970 Felis catus
397648 Sus scrofa
788087 Bos taurus
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