Browse our MCL-1 (MCL1) ELISA Kits

Full name:
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 ELISA Kits (MCL1)
On www.antibodies-online.com are 20 Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) ELISA Kits from 11 different suppliers available. Additionally we are shipping MCL-1 Antibodies (326) and MCL-1 Proteins (12) and many more products for this protein. A total of 378 MCL-1 products are currently listed.
Synonyms:
AW556805, bcl2-L-3, BCL2L3, EAT, mcl-1, MCL1-ES, mcl1/EAT, MCL1L, MCL1S, TM

More ELISA Kits for MCL-1 Interaction Partners

Mouse (Murine) Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) interaction partners

  1. miR (show MLXIP ELISA Kits)-32/MCL-1 pathway members were identified as key early genetic events driving melanoma progression.

  2. GSK3B (show GSK3b ELISA Kits)-MCL1 signaling to regulate axonal autophagy might be important for the successful completion of Wallerian degeneration.

  3. Specific downregulation of Mcl-1 significantly increases apoptosis of peritoneal macrophages and that the MAPK (show MAPK1 ELISA Kits) signaling pathway is the primary mediator of Mcl-1 expression.

  4. MCL1 plays a pivotal role in Leydig-cell steroidogenesis, and might provide novel insights into metabolic regulation in this cell

  5. Although loss of one Mcl-1 allele did not noticeably impair the survival of normal B lymphoid cells, it markedly diminished the survival of Proto-Oncogene (show RAB1A ELISA Kits) Proteins c-myc (show MYC ELISA Kits) overexpressing B cell progenitors.

  6. MCL-1 loss in early B-lymphoid progenitors delayed MYC (show MYC ELISA Kits)-driven lymphomagenesis.

  7. High Mcl-1 levels enhanced mTOR (show FRAP1 ELISA Kits) phosphorylation and augmented the differentiation of terminal effector cells and effector memory CD8 (show CD8A ELISA Kits) T cells.

  8. Data suggest Leishmania donovani exploits host anti-apoptotic protein MCL-1 to prevent apoptosis of host macrophages upon treatment with antiparasitic agents; thus, L. donovani protects its host, a factor in progression of visceral leishmaniasis.

  9. Data demonstrate that soluble factors from MM cells are able to generate MDSC through Mcl-1 upregulation.

  10. a mechanism of inverse coregulation between BECN1 (show BECN1 ELISA Kits) and MCL1 significantly contributes to their opposing roles in tumorigenesis

Human Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) interaction partners

  1. review summarizes the role of MCL-1 in B- and T-cell lymphoma

  2. Inhibition of SPHK1 (show SPHK1 ELISA Kits) in human acute myeloid leukemia (show BCL11A ELISA Kits) cells induces MCL1 degradation and caspase (show CASP3 ELISA Kits)-dependent cell death.

  3. bone marrow stroma is capable of inducing Mcl-1 dependence through the production of the plasma cell survival cytokine interleukin-6 (IL-6 (show IL6 ELISA Kits)).

  4. Mcl-1 is required for endothelial cell survival and the regulation of Ang II (show AGT ELISA Kits)-induced endothelial cell death.

  5. Repression of Mcl-1 and disruption of the Mcl-1/Bak (show BAK1 ELISA Kits) interaction in myeloma cells couple ER stress to mitochondrial apoptosis triggered by thapsigargin.

  6. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1) expression and c-Jun N-terminal kinase 1 (JNK1 (show MAPK8 ELISA Kits)) activation and subsequent Bcl-xL (show BCL2L1 ELISA Kits) protein degradation.

  7. Knockdown of endogenous Mcl-1 by RNA interference significantly accelerated the repair of DNA lesions in glycochenodeoxycholate-treated cells. However, unlike XRCC1 (show XRCC1 ELISA Kits), poly(ADP-ribose) polymerase (show PARP1 ELISA Kits) was induced following Mcl-1 knockdown. Conversely, poly(ADP-ribose) polymerase (show PARP1 ELISA Kits) suppression was observed following glycochenodeoxycholate treatment of cells overexpressing Mcl-1

  8. identified the apoptotic regulator MCL-1 as the only pro-survival BCL-2 (show BCL2 ELISA Kits) family member to be highly expressed throughout all human T-NHL (show RTEL1 ELISA Kits) subtypes

  9. these results suggest that SIRT6 (show SIRT6 ELISA Kits) enhances cell aggressiveness in PTC (show F9 ELISA Kits) via BRAF (show BRAF ELISA Kits)/ERK (show EPHB2 ELISA Kits)/Mcl1 pathway, and thus may be a promising target in the treatment of the disease.

  10. The expression of MCL-1 in prostate cancer tissues was much higher than that in normal prostate tissues.

MCL-1 (MCL1) Antigen Profile

Antigen Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Alternative names and synonyms associated with MCL-1 (MCL1)

  • myeloid cell leukemia sequence 1 (Mcl1) Elisa Kit
  • myeloid cell leukemia sequence 1 (BCL2-related) (MCL1) Elisa Kit
  • AW556805 Elisa Kit
  • bcl2-L-3 Elisa Kit
  • BCL2L3 Elisa Kit
  • EAT Elisa Kit
  • mcl-1 Elisa Kit
  • MCL1-ES Elisa Kit
  • mcl1/EAT Elisa Kit
  • MCL1L Elisa Kit
  • MCL1S Elisa Kit
  • TM Elisa Kit

Protein level used designations for MCL1

bcl-2-related protein EAT/mcl1 , induced myeloid leukemia cell differentiation protein Mcl-1 homolog , bcl-2-like protein 3 , induced myeloid leukemia cell differentiation protein Mcl-1 , myeloid cell leukemia ES , myeloid cell leukemia protein 1

GENE ID SPECIES
17210 Mus musculus
60430 Rattus norvegicus
4170 Homo sapiens
403537 Canis lupus familiaris
493970 Felis catus
397648 Sus scrofa
788087 Bos taurus
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